My HomepageMy homepage is at http://coturnix.org. It is temporarily stripped to minimal information, but more will come soon.
Search This Blog:
There are no public comments available to display.
- Lindau Nobel - interview with Ghada Al-Kadamany
- Postscript to Pittendrigh's Pet Project - Phototaxis, Photoperiodism and Precise Projectile Parabolas of Pilobolus on Pasture Poop
- Food goes through a rabbit twice. Think what that means!
- BIO101 - Physiology: Coordinated Response
- BIO101 - Physiology: Regulation and Control
- The PepsiGate linkfest
- The Ecological and Economic Importance of Sharks, Threats They Face, and How You Can Help (CANCELLED)
- A couple of Big Announcements about The Open Laboratory
- BIO101 - Introduction to Anatomy and Physiology
- Journalists need a point of view if they want to stay relevant theconversation.com/journalists-ne… via @US_Conversation 2 hours ago
- Why you should use Twitter during your PhD wp.me/pX3kK-1D6 via @thesiswhisperer 6 hours ago
- Eye of the <del>/Tiger</del> Green Anole anoleannals.org/2014/10/24/eye… 6 hours ago
- On a Decade of Getting Pooped On By Birds - lastwordonnothing.com/2014/10/23/on-… 12 hours ago
- Milk Grown in a Lab Is Humane and Sustainable. But Can It Catch On? on.natgeo.com/1yZ6F0n via @NatGeo 17 hours ago
- Reef sharks may already be adapted for climate change conservationmagazine.org/2014/10/reef-s… 22 hours ago
- Four secrets your goldfish is hiding from you bbc.com/earth/story/20… 23 hours ago
- Lemony Snicket's A Series of Unfortunate Events used highly self-conscious, experimental literary techniques theatlantic.com/entertainment/… 23 hours ago
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.
Monthly Archives: July 2006
One way to measure the fears of people in power is by the intensity of their quest for certainty and control over knowledge.
By that standard, the members of the Florida Legislature marked themselves as the folks most terrified of history in the United States when last month they took bold action to become the first state to outlaw historical interpretation in public schools. In other words, Florida has officially replaced the study of history with the imposition of dogma and effectively outlawed critical thinking.
Will there be a series of trials (Scopes, Arkansas, Dover…) about teaching history in schools over the next century? Oh, and definitely read the rest of the article – it is excellent!
It has been known for decades that scheduled meals can entrain the circadian clock. In some species (e.g., in some birds), regular timing of feeding entrains the main circadian system of the body in the suprachiasmatic (SCN) area of the hypothalamus, the retina and the pineal. In other species (e.g., rodents), it appears that the food-entrainable oscillator is anatomically and functionally distinct from the main pacemaker in the SCN.
Researchers working on different species discovered different properties and different anatomical locations for the food-entrainable clock. Now, a study from UT Southwestern Medical Center takes yet another look at the location of the food clock in mice, using expression of Period, a canonical clock gene, as the marker for the clock activity:
Timing of Food Consumption Activates Genes in Specific Brain Area:
The researchers put the mice on a 12-hour light/dark cycle, and provided food for four hours in the middle of the light portion. Because mice normally feed at night, this pattern is similar to humans eating at inappropriate times. Dysfunctional eating patterns play a role in human obesity, particularly in the nocturnal eating often seen in obese people, the researchers note.
The mice soon fell into a pattern of searching for food two hours before each feeding time. They also flipped their normal day/night behavior, ignoring the natural cue that day is their usual time to sleep. After several days, the researchers found that the daily activation cycle of Per genes in the SCN was not affected by the abnormal feeding pattern.
However, in a few different areas of the brain, particularly a center called the dorsomedial hypothamalic nucleus or DMH, the Per genes turned on strongly in sync with feeding time after seven days. When the mice subsequently went two days without food, the genes continued to turn on in sync with the expected feeding time.
I wonder what would have happened if instead of fasting, they gave food ad libitum at the end of the experiment. Also, what would have happened if either the whole experiment or that last 2-day bit was performed in constant darkness?
The paper is coming out on August 8 in PNAS. If there is something in the paper that the press release did not get right, I’ll be sure to tell you at that time.