ScienceOnline2010 – interview with Jonathan Eisen

Continuing with the tradition from last two years, I will occasionally post interviews with some of the participants of the ScienceOnline2010 conference that was held in the Research Triangle Park, NC back in January. See all the interviews in this series here. You can check out previous years’ interviews as well: 2008 and 2009.
Today, I asked Jonathan Eisen of Tree Of Life blog (and Academic Editor in Chief of PLoS Biology) to answer a few questions.
Welcome to A Blog Around The Clock. Would you, please, tell my readers a little bit more about yourself? Where are you coming from (both geographically and philosophically)? What is your (scientific) background?
Jonathan Eisen pic.jpgI am an evolutionary biologist interested in how organisms invent new functions. In particular I am interested in what causes differences in this “evolvability” between organisms. Or, in other words, the evolution of evolvability. I study this mostly in microbes, because, well, microbes rock.
I was born in Boston, MA and grew up in Bethesda, MD.
Tell us a little more about your career trajectory so far: interesting projects past and present?
In terms of background – I have always been interest in microbes and their evolution. Though I do not remember, I even wrote an essay on this in 9th grade.
In college (Harvard) I was originally an East Asian Studies major but switched to Biology after coming to my senses. I worked in multiple labs as an undergrad, first studying hummingbird circadian rhythms, then plant physiological ecology, and then found my true calling by working in a lab studying deep sea organisms and the microbial symbionts that live inside of them. I liked it so much I worked in the lab after graduating.
I then went to grad school at Stanford, originally to work on butterfly evolution, but then came to my senses and switched to working on how microbes protect their genomes from mutations (and in particular, why the mutation rates and patterns varied within and between species).
After getting that PhD thing I moved to The Institute for Genomic Research, where I was for eight years, and there I worked on sequencing microbial genomes and also on developing computational methods to study the evolution of microbes via analysis of their genome sequences.
Finally, I moved to where I am now – UC Davis. I moved here b/c of many things: (1) they have one of the best evolution and ecology departments in the country (2) my wife is from Berkeley and Davis, (3) we wanted to be closer to family in N. California (4) I like small towns that are obsessed with cycling (like Davis).
What is taking up the most of your time and passion these days? What are your goals?
(1) I want to create a full and complete field guide to microbes.
(2) I want all the worlds scientific publications to be free (really free, not just at no cost – free as in freedom, that is)
(3) I live for my kids, Analia (5) and Andres (3).
What aspect of science communication and/or particular use of the Web in science interests you the most?
I think the most interesting and important thing is accelerating the pace of scientific discovery and education through the use of a combination of tools (web included) as well as opening up the restrictions that have been historically placed on knowledge (e.g., fees for access).
How does (if it does) blogging figure in your work? How about social networks, e.g., Twitter, FriendFeed and Facebook? Do you find all this online activity to be a net positive (or even a necessity) in what you do?
All these have been very important in communicating with the broader world. I view all of these things as tools to experiment with. None are good or bad in and of themselves but all can be used to communicate science.
When and how did you first discover science blogs? What are some of your favourites? Have you discovered any cool science blogs by the participants at the Conference?
Not sure when I discovered them. I think when I went to SciFoo camp years ago I really became aware of the potential value of blogging. My favorites come and go. I try to sample from lots of different ones and not read the same ones over and over. Just like with scientific journals and scientific papers, some are good, some are bad but most are a mix, with bad and good and everything in between. So I like to look around at different ones, more by topic than by author.
What was the best aspect of ScienceOnline2010 for you? Any suggestions for next year? Is there anything that happened at this Conference – a session, something someone said or did or wrote – that will change the way you think about science communication, or something that you will take with you to your job, blog-reading and blog-writing?
Well, I already blogged about this here (tongue in cheek post about what was bad at the meeting – this is really about what was good in case you can’t tell )
And I also wrote about what I learned at the meeting here.
The meeting was great, hands down.
It was so nice to see you again and thank you for the interview. I hope to see you again next January.

Today’s carnivals

Berry Go Round #26 is up on Gravity’s Rainbow
Grand Rounds – the Health Care Reform Edition – are up at See First
Friday Ark #288 is up on Modulator

Clock Quotes

Our greatest glory is not in never falling, but in rising every time we fall.
– Confucius

New and Exciting in PLoS ONE

There are 9 new articles in PLoS ONE today. As always, you should rate the articles, post notes and comments and send trackbacks when you blog about the papers. You can now also easily place articles on various social services (CiteULike, Mendeley, Connotea, Stumbleupon, Facebook and Digg) with just one click. Here are my own picks for the week – you go and look for your own favourites:
Delimiting Species without Nuclear Monophyly in Madagascar’s Mouse Lemurs:

Speciation begins when populations become genetically separated through a substantial reduction in gene flow, and it is at this point that a genetically cohesive set of populations attain the sole property of species: the independent evolution of a population-level lineage. The comprehensive delimitation of species within biodiversity hotspots, regardless of their level of divergence, is important for understanding the factors that drive the diversification of biota and for identifying them as targets for conservation. However, delimiting recently diverged species is challenging due to insufficient time for the differential evolution of characters–including morphological differences, reproductive isolation, and gene tree monophyly–that are typically used as evidence for separately evolving lineages. In this study, we assembled multiple lines of evidence from the analysis of mtDNA and nDNA sequence data for the delimitation of a high diversity of cryptically diverged population-level mouse lemur lineages across the island of Madagascar. Our study uses a multi-faceted approach that applies phylogenetic, population genetic, and genealogical analysis for recognizing lineage diversity and presents the most thoroughly sampled species delimitation of mouse lemur ever performed. The resolution of a large number of geographically defined clades in the mtDNA gene tree provides strong initial evidence for recognizing a high diversity of population-level lineages in mouse lemurs. We find additional support for lineage recognition in the striking concordance between mtDNA clades and patterns of nuclear population structure. Lineages identified using these two sources of evidence also exhibit patterns of population divergence according to genealogical exclusivity estimates. Mouse lemur lineage diversity is reflected in both a geographically fine-scaled pattern of population divergence within established and geographically widespread taxa, as well as newly resolved patterns of micro-endemism revealed through expanded field sampling into previously poorly and well-sampled regions.

A Mathematical Model of Sentimental Dynamics Accounting for Marital Dissolution:

Marital dissolution is ubiquitous in western societies. It poses major scientific and sociological problems both in theoretical and therapeutic terms. Scholars and therapists agree on the existence of a sort of second law of thermodynamics for sentimental relationships. Effort is required to sustain them. Love is not enough. Building on a simple version of the second law we use optimal control theory as a novel approach to model sentimental dynamics. Our analysis is consistent with sociological data. We show that, when both partners have similar emotional attributes, there is an optimal effort policy yielding a durable happy union. This policy is prey to structural destabilization resulting from a combination of two factors: there is an effort gap because the optimal policy always entails discomfort and there is a tendency to lower effort to non-sustaining levels due to the instability of the dynamics. These mathematical facts implied by the model unveil an underlying mechanism that may explain couple disruption in real scenarios. Within this framework the apparent paradox that a union consistently planned to last forever will probably break up is explained as a mechanistic consequence of the second law.

Words and Melody Are Intertwined in Perception of Sung Words: EEG and Behavioral Evidence:

Language and music, two of the most unique human cognitive abilities, are combined in song, rendering it an ecological model for comparing speech and music cognition. The present study was designed to determine whether words and melodies in song are processed interactively or independently, and to examine the influence of attention on the processing of words and melodies in song. Event-Related brain Potentials (ERPs) and behavioral data were recorded while non-musicians listened to pairs of sung words (prime and target) presented in four experimental conditions: same word, same melody; same word, different melody; different word, same melody; different word, different melody. Participants were asked to attend to either the words or the melody, and to perform a same/different task. In both attentional tasks, different word targets elicited an N400 component, as predicted based on previous results. Most interestingly, different melodies (sung with the same word) elicited an N400 component followed by a late positive component. Finally, ERP and behavioral data converged in showing interactions between the linguistic and melodic dimensions of sung words. The finding that the N400 effect, a well-established marker of semantic processing, was modulated by musical melody in song suggests that variations in musical features affect word processing in sung language. Implications of the interactions between words and melody are discussed in light of evidence for shared neural processing resources between the phonological/semantic aspects of language and the melodic/harmonic aspects of music.

ScienceOnline2010 – interview with Misha Angrist

Continuing with the tradition from last two years, I will occasionally post interviews with some of the participants of the ScienceOnline2010 conference that was held in the Research Triangle Park, NC back in January. See all the interviews in this series here. You can check out previous years’ interviews as well: 2008 and 2009.
Today, I asked Misha Angrist from Duke (and the blog GenomeBoy), the fourth person in the Personal Genome Project whose entire genome was sequenced (thus one of the first 20 humans with a sequenced genome), to answer a few questions.
Welcome to A Blog Around The Clock. Would you, please, tell my readers a little bit more about yourself? Where are you coming from (both geographically and philosophically)? What is your (scientific) background?
Misha Angrist pic.jpgI was born and raised in Pittsburgh, PA. I bleed black and gold (though I wish the Steelers’ current quarterback weren’t such an asshat).
At some point after undergrad in the 1980s I decided I should be a genetic counselor. By the time I had the master’s degree and was getting ready to take my boards I realized I was not the guy who should be telling distraught people that their babies had serious problems.
The fortuitous thing was that my master’s thesis research took me to Duke and I had a wonderful few months working in a lab doing human genetics. In fact, I had so much fun I decided to get a PhD, which I finished in 1996. I hung around for a postdoc and overstayed my welcome. I realized that to succeed as a human geneticist (or genomicist) I would have to become a computational biologist, a statistical geneticist or a biochemist. I was not up to any of those tasks. (Are you sensing a pattern here?)
I wandered in the desert for a while. I dabbled in market research and biotech finance, where I succeeded in losing a small fortune in a short period of time. While I was bouncing from one epic fail to another, I managed to get an MFA from the Bennington Writing Seminars, which was wonderful on many levels.
This led me back to Duke where I took a job as a science editor. Eventually, when it became clear I was doing the work of a faculty member, I became an Assistant Professor. I can say without a single iota of snarkiness or insincerity that I feel extremely blessed to be where I am today.
What is taking up the most of your time and passion these days? What are your goals?
My book, Here is a Human Being: At the Dawn of Personal Genomics, will be published in November by Smithsonian Books/HarperCollins. I am in the middle of editing it and trying to figure out how I can help make it successful.
Meanwhile, I am teaching science writing, genome policy stuff, and developing and writing grants and papers related to personal genomics, i.e., living the life of an academic.
What aspect of science communication and/or particular use of the Web in science interests you the most?
I don’t know that I can offer a single answer. Certainly, at or near the top of the list is the kind of health-related stuff Thomas Goetz discusses in his terrific book, The Decision Tree. But what we’re living through is much bigger than science. I think the fact that citizens are now able to cut out the middleman, for better or worse (I tend to think it’s more often for the better), is really what fascinates me the most. This applies to all kinds of things. So, for example, I can buy a car on eBay and have it delivered to my house. I can text money to Haiti instantaneously. I can listen to On The Media while I walk my dog, I can send my parents pictures of their grandkids during their piano recital. I can order a genome scan online and see what it might mean for free at SNPedia. If I get really bummed out, I can watch Keyboard Cat for a few minutes. And thanks to people like you, I can read PLoS One and other journals for free and see what folks are saying about the latest and greatest (or not) in science.
How does (if it does) blogging figure in your work? How about social networks, e.g., Twitter, FriendFeed and Facebook? Do you find all this online activity to be a net positive (or even a necessity) in what you do?
I wish I knew. I think I can safely say that I will never be among the hallowed SEED science bloggers. The only way that would happen would be if they started handing out awards for infrequent and irrelevant posts. Sometimes I feel guilty about my desultory approach.
That said, Lizzie Skurnick, a fantastic writer who introduced me to blogging lo these many years ago, gave me simple advice that has served me well: blog about what interests you, about whatever your passions. For me, an ADHD kinda guy, this might mean discussing whether pharmacogenetic testing for anticoagulant response is ready for primetime, or posting a YouTube of Prince playing the bejeezus out of While My Guitar Gently Weeps.
As for frequency, it’s kind of a do-as-I-say-not-as-I-do thing. I am a beneficiary of people like you, who compulsively update their blogs. My life would be poorer if not for regular updates from Genetic Future, Genomics Law Report, and a dozen others. But GenomeBoy.com will never compete with those folks. For me, blogging often feels like a luxury I can’t afford or homework I can’t finish.
I’ve only been tweeting for a month and I have to say, it makes me crazy sometimes and I’m already crazy. I expect to be on Facebook soon, though I’m kind of dreading it. FriendFeed? I don’t even know what that is.
When and how did you first discover science blogs?
I can’t remember how I discovered them – it might have been via Jason Bobe and The Personal Genome (which he rarely updates anymore, sadly). It didn’t happen overnight, but at some point it became clear to me that whatever one was interested in, there were blogs out there catering to those interests. I’ve spent much of my adult life doing and thinking about genetics and genomics and their implications, so I gravitate toward blogs that engage with those subjects: Genetic Future, Genomics Law Report, Gene Sherpas, Eye on DNA, The Genetic Genealogist, The Spittoon, DNA Direct Talk etc. But of course there are other great ones: Culture Dish, Terra Sigillata, John Hawks. I’m forgetting a bunch.
Two blogs I discovered specifically via ScienceOnline were Adventures in Ethics and Science and Neuron Culture. Janet Stemwedel and David Dobbs are two of the more thoughtful and compelling writers in the blogosphere.
What was the best aspect of ScienceOnline2010 for you? Any suggestions for next year? Is there anything that happened at this Conference – a session, something someone said or did or wrote – that will change the way you think about science communication, or something that you will take with you to your job, blog-reading and blog-writing?
I thought 2010 was the best year yet! I think part of it is the natural evolution of the medium. Only a few years ago, to say you were a blogger, let alone that you were going to hang out with 150 other bloggers for the weekend, was to invite a blank stare, suspicion or ridicule. And I admit that I was skeptical about that first conference. I didn’t realize that so many people cared so much.
This year was extraordinary. The sessions on blog-to-book, fact-checking and rebooting science journalism were outstanding. Partly because they were applicable to my professional life, partly because they transcended blogging and got to the heart of perennial issues in science communication, and partly because the people involved – David Dobbs, Rebecca Skloot, Ed Yong, Carl Zimmer, John Timmer, Tom Levenson, Brian Switek, Sheril Kirshenbaum – were so bright, charming and wise. I wish every meeting I went to was so fulfilling and I only spent two abbreviated days there.
I also had the pleasure of meeting Henry Gee, Senior Editor at Nature, whose book, Jacob’s Ladder, is that rare combination of history, science and culture, and was ahead of its time.
My only suggestion: is there any way the conference could be pushed back to February? I always want my Duke students to attend, but this year ScienceOnline took place before the end of drop and add, so logistically it was a bit more difficult.
It was great to see you again and thank you for the interview. I hope you will be able to attend again next January.

Clock Quotes

It takes time for the absent to assume their true shape in our thoughts. After death they take on a firmer outline and then cease to change.
– Sidonie Gabrielle Claudine Colette

ScienceOnline2010 – interview with Ed Yong

Continuing with the tradition from last two years, I will occasionally post interviews with some of the participants of the ScienceOnline2010 conference that was held in the Research Triangle Park, NC back in January. See all the interviews in this series here. You can check out previous years’ interviews as well: 2008 and 2009.
Today, I asked Ed Yong from Not Exactly Rocket Science to answer a few questions.
Welcome to A Blog Around The Clock. Would you, please, tell my readers a little bit more about yourself? Where are you coming from (both geographically and philosophically)? What is your (scientific) background?
Ed Yong pic.jpgI’m Ed, I talk to people about science and I do it in three main ways. I write a science blog called Not Exactly Rocket Science, I do a fair bit of freelance journalism for British press, and I work in a science communications role for a big UK cancer charity. Round about the time that swine flu was saturating the headlines, I started calling myself a triple-reassortant science writer, which is a seriously geeky affectation but worth it for the occasional person who gets it and sniggers.
In terms of my background, I did a degree in Natural Sciences at Cambridge, covering all sorts of fields from animal behaviour to experimental psychology. I assumed that research was going to be my calling and I spent a year or so as a PhD student before realising that I was apocalyptically bad at it. Mythically bad. People composed ballads about how much I sucked. If I didn’t destroy the world during my time in the lab, it’s only because that would probably have counted as a publishable result.
Thankfully, the insight that I sucked at doing science coincided nicely with the revelation that I wasn’t too bad at talking about it. Essentially, I can’t narrow my attentional spotlight on a single subject; I need broad vistas. I can’t derive motivation from rare but transcendental moments of success amid a long drought of failure; I need a more regular fix. And my hands are clumsy and inept when handling a Gilson; they’re much better at dancing on a keyboard. And thus concludes my origin story. Maybe I should have just lied and said something about being bitten by a radioactive David Attenborough.
Moving on to here and now, I’m constantly excited by the new discoveries that I read about and I’m keen to infect other people with the same enthusiasm. I just think that people will be better off if they have a deeper understanding of the world around them and if they’re motivated to sceptically seek out that knowledge in the first place. Telling awe-inspiring stories about science is one way of achieving both those ends. My own love for science was fuelled by masterful communicators and I want to carry on that tradition.
Oh, and I live in London, a great, beautiful, cosmopolitan, culturally vibrant city that has the god-awful problem of being full of Londoners.
Tell us a little more about your career trajectory so far: interesting projects past and present?
At the moment, I’m essentially juggling two careers, one during the day and one at night. Like Batman but with more repetitive strain injury. During the day, I work at Cancer Research UK and carry the marvellously high-falutin’ job title of Head of Health Evidence and Information. My job is to ensure that our information on cancer prevention and early detection is evidence-based and to use that evidence to guide the rest of the charity. It’s a great mix of leading a small team, media interviews, reviewing literature, acting as a sort of consultant to other teams, and a fair bit of writing.
At night, I put on my journalist and blogger hats (they’re figurative hats, although if they were real, the journalist one would be one of those old fedoras with a Press pass sticking out of it, and the blogger one would be something silly but combative, like a conquistador helmet). I started blogging because I wanted to flex my writing muscles on different topics and in a style that’s more naturally mine. I also had visions of being a ‘proper’ science writer but wasn’t getting any traction sending pitches into mainstream media. So, I started doing it myself. I started on WordPress and was recruited to ScienceBlogs just over two years ago. The blog has gone from strength to strength and the last couple of months have been record-breakers in terms of traffic. This week has been the most rewarding yet. I won the top prize at the Research Blogging Awards as well as prizes for best post and best lay-level blog. And I’ve just begun Phase Three of the NERS life cycle by jumping into a new host body at Discover Blogs, where I’m tremendously excited to be joining a small but elite group of bloggers.
I also do a fair bit of freelancing – some news pieces in the past but mostly features at the moment. I’ve written for New Scientist, the Times, the Guardian, Nature and a number of other publications. And I’ve won a couple of writing awards too, including the Daily Telegraph Science Writer Award that really kick-started all of this off, and the Association of British Science Writers’ Best Newcomer award last year. Actually, the certificate for that says Ed Young, but I distinctly remember collecting it and shaking someone’s hand.
What is taking up the most of your time and passion these days? What are your goals?
The big goals are these: constantly learn new things and better myself. Be good at what I choose to do but never become arrogant. Be an excellent husband, a good writer and not an idiot, in that order.
To elaborate, the lofty goal is to get as many people interested in science as possible. Make the complicated seem simple, the obscure seem fun and the unknown seem tangible. My writing career is still in its infancy and I have no illusions about how far I have to learn. NERS is still the single piece of work that I am proudest of and I want to build it into a widely respected source of science news. It’s starting to get some mainstream recognition. That’s obviously personally fulfilling but I think that as part of a general trend, it would be prudent for both blogs and mainstream media to starting collaborating more. I want to continue to work for a good cause during my day job, keep on doing longer features for mainstream media and speak at more events. And at some point in the next 5 years, I would love to start writing popular science books. The problem is that I can’t think of a plan that involves me achieving all of these things without violating at least a few laws of physics. For the moment, I appear to have achieved time saturation.
I’m also keen to carry on absorbing ideas. The worlds of journalism, the Internet and, indeed, science itself are changing at a dizzying pace and it can feel like a massive treadmill, where we’re all running faster to stay in the same place like Caroll’s Red Queen. In the last year alone, my thoughts on journalism have changed significantly just through thinking about the field, reading commentaries from others and chatting to my peers. And all the while, I see people who have dug their heels in, stagnated in their opinions, and are slowly drifting back down the treadmill towards some extinction horizon. I would very much like to not be those people. The minute I think I’ve got this all figured out is the minute I really haven’t. So… more reading, mulling and discussing.
Other than that, I don’t really believe in detailed life plans. The most exciting things I’ve done over the past few years have come about through unpredictable openings and I think that successful people are the ones with the nous to capitalise on the right opportunities as they come along. With the gift of hindsight, even chaotic bumbling can look like some sort of structured plan.
What aspect of science communication and/or particular use of the Web in science interests you the most?
As far as science communication goes, there are two things that I love above all else. The first is finding a way of successfully explaining something complicated. Getting the right angle, metaphor or play on words is just magical. It’s like scoring a winning goal or finally getting an experiment to work or reaching the peak of a mountain, except I get to do it… every… single… day. The second is related – finding a narrative that links an entire field, or several different fields. This is why I write features. It’s an entirely different skill to writing posts based on single papers. It often involves drawing out massive spider diagrams and finding an easy route between all the nodes. And again, that moment when everything clicks into place, when you know how every paragraph will flow into every other, and when you can see the story beats… it’s just transcendental.
As far as the internet goes, I’ve written about this extensively on my own blog. I’m fascinated by the way that the internet is changing the face of science journalism, how it’s altering the very definition of a science journalist, how it can be used to reach mass audiences while simultaneously failing to do so, and the massive, incalculable implications of opening the tools of production to everyone. Simply put, I would not have this career without the Internet. I absolutely love the fact that a complete nobody like me can waltz in and start writing, and a couple of years later, I’ve spoken at an international conference, I’ve been published in most of the British press that I love and I’ve interviewed David Attenborough, my childhood hero, in his living room. I could kiss the Internet, but I know where it’s been.
How does (if it does) blogging figure in your work? How about social networks, e.g., Twitter, FriendFeed and Facebook? Do you find all this online activity to be a net positive (or even a necessity) in what you do?
I’ve already spoken about the blogging. My Twitter experience is about a year old and it has been an unexpected joy. There are obvious benefits – it’s great for publicity, getting more traffic, building a brand, chatting to like-minded people and so on. It also allows me to do things that I try to limit on my blog, like promoting other people’s stuff, linking heavily, being a bit sillier, chatting to friends, pointing out stupid stuff in the popular press, linking to geekery, and so on. I want to keep the signal-to-noise ratio high on the blog but it’s a different sort of signal on Twitter. For better or worse, my Twitter stream is probably closer to my actual personality than my blog is.
Twitter is also an absolutely amazing source of information. Tweetdeck is essentially my own personal newspaper that’s edited by the people I follow – a cadre of excellent journalists, scientists and friends who I trust to feed me interesting content. The thing that critics of the internet don’t get is that you can filter your way out of the noise with relative ease. It’s much like flesh-and-blood life – you get the most out of your conversations if you choose interesting people to hang around.
As a science writer, it’s invaluable too. I’ve used Twitter to source contacts for articles, clarify complex terms, get papers I don’t have access to and even commission a guest post on my blog. One of my followers even helped me to kill a pesky virus on my computer! I even think that Twitter makes quite good practice for a writer. People slate the 140-character format but I think it’s actually fairly demanding as a discipline. You have to work harder to be understood in a limited space, especially if you’re debating with someone. On the downside, there are the obvious negatives – it’s a massive time-suck and I personally find it very addictive. But there’s no question in my mind that it’s a net-positive thing.
When and how did you first discover science blogs? What are some of your favourites? Have you discovered any cool science blogs by the participants at the Conference?
I probably started writing a science blog before I started reading them. I devote most of my free time to writing and I get far too little time to read what everyone else is doing than I would like. I use Twitter to find stuff that interests me and there are only a few blogs that I follow religiously. To be honest, I’m far more interested in individuals as writers rather than in blogs as entities. Given that there’s so much cross-pollination between blogs, mainstream media and other formats, it makes little sense to me to focus on blogs just because I write one. I love good science writing, regardless of the format. And one of the interesting things about social media is that a person’s entire (I shudder to say it) brand affects how I view them – it’s about writing skill, but also whether they’re fun to chat to, whether they voice interesting opinions and whether they point towards interesting stuff.
In terms of people I rate, a list of science writojournobloggocommunicators would have to include Carl Zimmer, Vaughan Bell, Brian Switek, SciCurious, Jonah Lehrer, Brandon Keim, Alexis Madrigal, Matthew Herper, Mark Henderson, Ivan Oransky, Rebecca Skloot, David Dobbs, John Timmer, Adam Rutherford, Sheril Kirshenbaum, Brendan Maher, Christie Wilcox, Daniel Cressey, Jennifer Ouellette, Frank Swain, Simon Frantz, Martin Robbins, PalMD, Daniel Macarthur, etc. I’m also loving the opportunity to chat to loads of great up-and-coming science journalists on Twitter, like Ferris Jabr, Christine Ottery, Colin Schultz, Mike Orcutt, you obviously,… Look, I’m just scratching the surface here and I’m sure I’ve missed out people who I’ll feel awful about later. Have a look at my blogroll or the people I follow on Twitter. I do those for a reason.
What was the best aspect of ScienceOnline2010 for you? Any suggestions for next year? Is there anything that happened at this Conference – a session, something someone said or did or wrote – that will change the way you think about science communication, or something that you will take with you to your job, blog-reading and blog-writing?
The social side of the conference was unquestionably the best aspect for me. There is something fascinating and unique about meeting old friends for the first time. I’ve known people like SciCurious, Brian Switek and others for years. They’ve done favours for me and I for them and after all this history builds up, you finally get to see someone’s face and give them a hug – it’s bizarre, but a little part of me wonders how people ever met other people in a different way. It’s a dream scenario for an introvert. There is also something quite remarkable about seeing all these people, who know each other through online social networks, cementing their relationships in flesh and blood. It simultaneously shows that social media can be a glorious conduit for meeting people, but it can’t substitute for a good, old-fashioned handshake.
As to the conference itself, without being too self-promotional, I was very pleased with the session that I ran with Carl, David and John. I absolutely loved the entertainment session with Tamara Krinsky and Jennifer Ouellette and the pitching session with Rebecca Skloot, Clifton Wiens, David Dobbs and Ivan Oransky, a session I wish I’d come to several years ago. In general, I was inspired by how humble and down-to-earth everyone I met was. To some extent, this was probably confirmation bias but none of the journalists or scientists I spoke to had any airs, regardless of their experience or existing kudos. From experience, this is an outlier as far as such meetings go, but one I’m grateful for.
The thing that inspired me most in terms of my career was seeing how many people are immersed in a multitude of different roles and activities. They blog, write for mainstream media, make podcasts, shoot videos, teach… the list goes on. It’s an intriguing model and one that I will be paying close attention to. And the conference was largely about the opportunity for inspiring myself too. Agreeing to chair a panel gave me a chance to think hard about science journalism, its future and my place in it. It led to a couple of op/eds on my blog and a chance to test and develop my views on the field. More practically, it made me start thinking more carefully about interviewing other sources for the posts I write, and it led to the new Not Exactly Pocket Science feature on the blog. It has galvanised me into trying to make NERS the best possible home of science journalism that it can be.
As to next year, I think everyone should agree beforehand that if anyone gets ill, they immediately give their snotty tissues to Jonathan Eisen for phylogenetic comparison. That way, we can easily establish who Patient Zero was and we can dispel the scandalous rumours that it was me. Also given the number of sessions she ran this year, you might consider renaming the conference to SklootOnline 2011.
It was so nice to see you again and thank you for the interview. I hope to see you again next January.
This interview was cross-posted on Ed Yong’s blog so check out what kinds of comments he gets there.

You can now start submitting your blog posts for the Open Laboratory 2010

Now that the 2009 edition of Open Laboratory, the fourth annual anthology of the best writing on science blogs, is out and getting the first (very positive!) reviews on blog and in the media, it’s time to start looking ahead at the next year.
Yesterday I cleaned up the submission form, made the necessary edits, and opened it up – please go to the new Submission Form and start entering the posts you consider worthy of publishing in the book.
Each entry needs to be originally published as a blog post between December 1st 2009 and December 1st 2010 to be eligible.
You can nominate as many entries as you wish, written by you or by others.
Historically, about half of the submissions are nominated by readers and the other half by authors – there is no shame in self-promotion. Nobody knows your archives as well as you do, so dig through them, back to December 1st of last year, and pick a post or two to submit right now. Then, as the year progresses and you post more good stuff, come back and submit more.
History also shows that the number of entries you submit has no relation to your chances of getting picked. If your writing is good, a single submitted post has a chance. If it sucks, submitting 50 entries will not help (may actually bore the judges to death until they actively hate you for making them work so hard in an unlikely chance of picking something from that avalanche of posts).
Remember that this is going to be a book – printed on paper derived from dead trees, with black&white or grayscale images only. Until eReaders get really good at that and totally ubiqutous, audio and video files just don’t work on paper, so posts that rely heavily on those will not make it. Hyperlinks also do not work well on paper, so if your post relies on a number of external links, chances of that post getting printed are miniscule to zero (unless you can show how it can be edited and still be good). Can your post still be good if you eliminate pictures you don’t have copyright on? Or if you turn color images into grayscale? Go ahead, otherwise don”t bother – can’t be done. When judges sift through several hundreds of submissions in order to pick 52, posts that require lots of editing to make them fit for print are easy to cut out of the running. There is no reason not to edit a non-print-friendly post and repost it in a more print-friendly format before submitting it. In the end, if your entry gets into the final 52, you will be asked to do some editing anyway, and we may do some editing for you on top of that.
Bear in mind that one of the 52 posts that makes it into the book will be an original cartoon or comic strip. Also bear in mind that another one of the 52 posts that makes it into the book will be an original poem. And you are also encouraged to submit original art – if we are floored by it, we may decide to put it on the cover. The other 50 posts will be essays of different lengths, forms, formats, styles and voices, on 50 different topics, displaying the diversity, creativity and quality of writing in the science blogosphere.
If you also write for a magazine or newspaper as well as on a blog (independent blog or a blog hosted by a magazine/newspaper), please submit your blog posts and not your magazine/newspaper pieces. It does not matter if you are paid or not, but use this rule of thumb: if you posted out of your volition, on a topic you wanted to write about, it’s fine. If you wrote something because an editor asked you to, and this was subsequently edited and showed up on the main magazine/newspaper site online (and perhaps even in print), then it should not be submitted for this collection of (essentially amateur) work.
We want to see entries that discuss all areas of science, nature, environment, technology, health and medicine, as well as “meta” topics ranging from the Life in Academia, to women/minorities in science, to the intersection between science and policy (and politics) or religion, to skepticism, to history, philosophy and sociology of science, to the analysis of the science publishing world or science communication/journalism, to personal stories by scientists, to patient stories by physicians/nurses (or patients). Check out the 2006, 2007, 2008 and 2009 editions to see what kinds of posts made it in the past years.
There is a great diversity of writers in the science blogosphere. Some bloggers consciously target their peers as their main audience. While wonderfully written, such posts tend to have a little bit too much technical jargon (and even formulae) for the lay audience. The target audience of the anthology is lay audience. Actually, the target audience for the book is even more lay than the usual readers of science blogs. These books are supposed to be given as presents to your Mom, or your non-science friends, to show them both that science is cool and that there is great writing on blogs. So, when choosing which posts to enter, look for those that are gripping and exciting and also easy to understand by just about everyone.
Again, here is the Submission form so you can get started. The badges/buttons that make it easy to submit will be available soon (check this blog in a few days). The year’s editor will also be announced on this blog soon. You can also join our Facebook fan page here.
Under the fold are entries so far (I tweeted the link yesterday, so the cat is out of the bag) and, as always, I will keep reposting the growing list regularly throughout the year so you can keep checking here to see what’s already been submitted (no need to submit duplicates – we just delete those extras – once is sufficient):

Continue reading

Clock Quotes

There is time for work. And there is time for love. That leaves no other time.
– Coco Chanel

Clock Quotes

Creatures whose mainspring is curiosity enjoy the accumulating of facts far more than the pausing at times to reflect on those facts.
– Clarence Day

Week in review

This was a busy, crazy week.
On Monday and Tuesday I was in Boston. You may remember I went to Boston last year as well and for the same reason – spending a day at the WGNH studios, helping with the World Science project that combines radio, podcasts and online forums. You have probably noticed I have posted announcements of these throughout the year.
A short story airs on the radio show The World, about some science-related topic with a global angle. The same scientist (or physician, or science journalist) who is interviewed for a couple of minutes on air is also interviewed for 20 minutes for the podcast, and then keeps coming back for another week, responding to the questions on the online forum. Last year, that was just an idea we helped turn into reality – the website went live about a month or so later.
This year, we had something to look at and analyze – how did it go, where the traffic came from, etc, and could make suggestions for improvements for the next year. I hope that the insights from us, the outside consultants, is useful to the crew there. I personally felt that this year’s meeting was better and more productive – perhaps because we had the website and the statistics already in front of us, instead of just visualizing in our minds how this should look like.
The composition of outside consultants also changed over the year. Only Rekha Murthy and I were there from the last year’s lineup (see the first two links in this post for last year’s list). The new folks in the room were C.C.Chapman, Andy Brack and Adnaan Wasey and we quickly ‘clicked’ with each other and with the World/SigmaXi/Nova/PRI people so the business of the day was pleasant and productive.
I will keep pointing out the new podcasts/forums over the year here (and on Twitter/FriendFeed/Facebook) and I hope you give them a listen/read. And I hope I get invited to Boston again next year. I really like this project and think it can become big and popular over time. You can follow World-Science on Twitter, FriendFeed and Facebook and download their podcasts on iTunes.
Unfortunately, unlike last year, I was staying in Boston only one night and did not have time for a meetup/dinner with friends, bloggers and twitterers. If only I knew I’d spend six hours at Logan airport waiting for my flight home, I could have organized one. Eh, perhaps next year….
Being in Boston, I had to miss both Pecha Kucha Raleigh and this month’s Monti. Can’t get everywhere!
You already know I spent some time struggling with my laptop. I am also in the middle of teaching my BIO101 course, lectures on Wednesday nights, labs on Saturday mornings.
And yesterday, for the third year in a row, Abel Pharmboy and I went to Misha Angrist’s class to talk about science blogging, social networks and media. Last two years, Sheril was the third part of the trio, but as she just moved to Texas, we went without her. We’ll need a replacement for her next year, I guess. This is always a fun thing to do – Misha always has interesting, engaged students.
And tonight, we are off to the Salon of Music, Poetry, and Theater at Common Ground Theatre in Durham.

Clock Quotes

Of all tyrannies, a tyranny exercised for the good of its victims may be the most oppressive. It may be better to live under robber barons than under omnipotent moral busybodies. The robber baron’s cruelty may sometimes sleep, his cupidity may at some point be satiated; but those who torment us for our own good will torment us without end, for they do so with the approval of their consciences.
– Clive Staples Lewis

Best Biology posts on A Blog Around The Clock

Now that this blog has won the ResearchBlogging.org Award in the Biology category, people are coming here and looking for biology posts. And on a blog with almost 10,000 posts, they may not be easy to find. So, I put together a collection of posts that I think are decent under the fold. Different lengths, styles, topics, reading-levels – hopefully something for everyone:

Continue reading

Update, and question about computer problems

You may have noticed very sparse blogging last couple of days – just the pre-scheduled Clock Quotes…
Well, I have some laptop problems (Dell PC with WinXP, only FF as browser).
The first inklings of problems showed up right after the AAAS meeting last month. I have been dutifully cleaning with Symantec, Spyware Doctor, SUPERantispyware and Spybot Search&Destroy almost daily since then. My Malwarebytes does not work – after uninstalling it, I get an error when trying to reinstall. Ad-Aware does not let me start (says I am a wrong user for it). WTF?
The problem is this – Google sites give me 404, etc.:

Not Found
The requested URL /accounts/ServiceLogin was not found on this server.
Apache/2.2.3 (Red Hat) Server at http://www.google.com Port 443

I cannot get into Gmail, Google docs, do Google searches, etc. It started a few days ago by letting me access these (and other sites) by first asking me to View Certificate (I click No and it proceeds to the site). That happened on and off – the same website would sometimes ask sometimes not for this. On Monday/Tuesday in Boston, this did not happen at all on the hotel wifi. It did again in a cafe on their wifi, and then again when I got home. Now, if I have a saved search (e.g., Google Blogsearch for my blog URL) I can get there and see it and change search terms, etc., but if I try to click on any of the search items it forwards to a commercial/spam site instead. I also get 404 if I try to Log In my Google profile at any site.
All other sites on the WWW I can access just fine right now (and no call to view certificate either). I can check Gmail on iPhone but cannot download files, copy+paste, etc. from there. So, unless I can reply in two words, my response to your mail may be delayed until I get this fixed. Or re-send, if urgent, your message to my other e-mail: Bora@plos.org.
I have spent the whole day and night yesterday cleaning up the laptop with four different spy/mal/ad-ware/virus cleaners- they did not find much of concern.
The problem is not with the router – other family members using the same connection have no problems with their laptops.
Since my Internet Explorer does not work, I cannot afford to remove Firefox (if it is Firefox that is borked) as I cannot get back online afterwards to re-download it again. I cannot first download Chrome, because it is a Google product, so I get 404. Any other browsers I should try?
Any other ideas?

Some recent changes at Scienceblogs.com

If you are a regular reader of Scienceblogs.com, you have probably already learned that two of our blogs have moved over to Discover blogs.
Razib of Gene Expression has moved from here to his new digs over there. Read his Goodbye post on Sb and his Welcome post over at Discover.
Ed Yong of Not Exactly Rocket Science has moved from here to his new digs over there. Read his Goodbye post on Sb and his Welcome post over at Discover.
Razib and Ed are joining the small but elite blogging network, backed by the well-known Discover brand, the likes of Carl Zimmer, Phil Plait, Sean Carrol et al., Sheril Kirshenbaum and Chris Mooney, Andrew Moseman and Smriti Rao, plus NCBI ROFL, as well as their editorial blogs, e.g., 80 Beats aggregator, Rebecca Horne’s Visual Science and Science Not Fiction. I hope you change your bookmarks and subscriptions and follow Ed and Razib at their new place. As they say, once a SciBling, always a SciBling.
Science blogging networks are growing and multiplying. Each network, be it Scienceblogs.com, Nature Network, SciBlogs, Discover blogs, ScientificBlogging.org or others has a different approach, different goals, different style, different target audience… Some start many new people at blogging, nurture them and build them until some of them become brand-names on their own. Others lure in already very popular bloggers. Some focus strictly on science. Others give bloggers complete freedom to explore any topics they are interested in (hopefully with some intersection with science most of the time).
It is not surprising that individual bloggers, as they change and mature, find that a move to a different network (or even maintaining multiple blogs on multiple networks) better fits their own changing goals. Each network occupies a slightly different niche in the science blogging ecosystem, and more such networks exist, the better for science communication as a whole.
So, move by Ed and Razib from Sb to Discover is just a part of a regular shuffle. They did not disappear from the scene in any way. Is it a “loss” to Scienceblogs.com? Sure, in a way. But perhaps you noticed that Scienceblogs.com has grown quite a bit lately, adding a number of wonderful bloggers. Are you reading Observations Of A Nerd and Obesity Panacea and Universe and Oscillator and Casaubon’s Book and Dot Physics and Applied Statistics and Evolution for Everyone and Tomorrow’s Table and The Book of Trogool and Collective Imagination and Common Knowledge, among the newest additions to this very large stable of bloggers? Do you check The Last 24 Hours page every day? We had more bloggers join than leave lately. The network subtly changes over time. And that is how it goes. And that is a Good Thing.
Congratulations to Ed and Razib – we’ll follow you there, of course.

Clock Quotes

Time, for all its smuggling in of new problems, conspicuously cancels others.
– Clara Winston

Clock Quotes

I wanna do a better album each time. And if I cannot do that, I will not record.
– Celine Dion

ScienceOnline2010 – interview with Dennis Meredith

Continuing with the tradition from last two years, I will occasionally post interviews with some of the participants of the ScienceOnline2010 conference that was held in the Research Triangle Park, NC back in January. See all the interviews in this series here. You can check out previous years’ interviews as well: 2008 and 2009.
Today, I asked Dennis Meredith to answer a few questions.
Welcome to A Blog Around The Clock. Would you, please, tell my readers a little bit more about yourself? Where are you coming from (both geographically and philosophically)? What is your (scientific) background?
I’m originally from Texas, but my jobs have taken me all around the country. I’ve always been fascinated by science and received my B.S. in Chemistry from the University of Texas. However, I discovered my true calling when I went into the science writing program at the University of Wisconsin, where I received an M.S. in Biochemistry-Science Writing.
Tell us a little more about your career trajectory so far: interesting projects past and present?
Dennis Meredith pic.jpgFrom the UW science writing program, I got my first job in the UW Medical Center News Office as assistant director. After that, I took science writing jobs at the University of Rhode Island, MIT, Caltech, Cornell, and ended up at Duke as the Director of the Office of Research Communication. I was known as the DORC of Duke. Always pay attention to the acronym before you take the job! My most interesting project was the research news site EurekAlert!, which I conceived and helped AAAS develop. It now links more than 4,500 journalists to news from 800 subscribing research institutions.
What is taking up the most of your time and passion these days? What are your goals?
I “retired” from Duke three years ago. I put the word in quotes because I’m still doing full-time science writing and consulting. My biggest project now by far is promoting my book “Explaining Research“, published by Oxford University Press. And of course, there’s my blog, Research Explainer. My central goal is really to change the culture of science and engineering to value lay-level communications more. By giving scientists and engineers the communication tools and techniques they need–from news releases to video to blogging–I hope to increase their engagement with the public and their influence in such critical areas as global warming and science education.
What aspect of science communication and/or particular use of the Web in science interests you the most?
What fascinates me is the Web’s immense power to make each person a media outlet. What’s more, the stunning increase in power and lowered cost of media technologies such as video cameras means that everybody can be a print/radio/TV outlet. The challenge for me is helping some of the people who have the most important things to say–scientists and engineers–take advantage of these technologies.
How does (if it does) blogging figure in your work? How about social networks, e.g., Twitter, FriendFeed and Facebook? Do you find all this online activity to be a net positive (or even a necessity) in what you do?
I’ll admit some timidity when I started blogging. Even though I’ve been writing science for more than four decades, the idea of hitting a button and having my words instantly published was daunting. I’d always been “protected” by being in a magazine or part of a university news operation. Since then, blogging has not only become easier, but I’ve realized that it is a central tool in updating and expanding on the book. Since all the book’s references are online, I can easily insert a blog post into the references that contains new information or points I didn’t think of when I was writing the book.
When and how did you first discover science blogs? What are some of your favourites? Have you discovered any cool science blogs by the participants at the Conference?
I first discovered science blogs when I started blogging. I was delighted with the vast range of voices out there. I can’t really say what some of my favorite blogs are. It’s like asking which do you like better, tacos, ice cream, chardonnay, or oysters? I get something out of all the blogs I read, and each time I discover a new one, I find a refreshing new voice and new ideas. For me, however, the prototypical blog has been Bora’s–not to suck up to my host for this Q&A. I was struck from the beginning by Bora’s ability to so effectively blend science and communication issues in a blog, and this eclecticism has broadened my view of what a blog can and should be–a broad-ranging exploration of interesting issues, whatever they are.
What was the best aspect of ScienceOnline2010 for you? Any suggestions for next year? Is there anything that happened at this Conference – a session, something someone said or did or wrote – that will change the way you think about science communication, or something that you will take with you to your job, blog-reading and blog-writing?
By far the best aspect of each ScienceOnline conference has been walking into this electric atmosphere of creativity and getting a delightful, inspiring charge of energy and ideas. For ScienceOnline2010, the most productive sessions for me were those on blogging techniques, scientific visualization and video. For next year, I’d recommend a significant workshop on Web video techniques, in which participants are invited to bring their cameras, especially the pocket-sized ones, and create and edit videos. I’m now just beginning to learn how to make quality videos, and any coaching would help. What has surprised me as I’ve trained myself is how simple techniques of lighting, composition and audio can greatly improve videos.
It was so nice to see you again (as well as later at AAAS on our panel) and thank you for the interview. I hope to see you again next January.

ResearchBlogging Awards 2010

Research Blogging Awards 2010I was in Boston last two days, and mostly offline, so the news of the announcements of ResearchBlogging.org Awards found me on Twitter, on my iPhone during a brief break of the PRI/BBC/Nova/Sigma Xi/WGBH/The World meeting. Thus, apart from a couple of quick retweets, I did not have the opportunity until now to take a better look and to say something about it.
You can see the news at the Seed site and download the official press release. And listening to the podcast about the awards AND opening the envelopes with winners’s names is great fun.
Then, take some time to go through the list of all Winners and Finalists – check them out and bookmark those you like – these are the best of the best. The blogs were nominated by the broader science online community, the finalists were picked by a star-studded panel of judges, and the final winners were determined by votes of the members of the ResearchBlogging.org community.
First, in a tough competition of some brilliant bloggers, my SciBling Ed Yong of Not Exactly Rocket Science blog swept the board, and deservedly so. He won in three categories: Research Blog of the Year, Best Lay-Level blog and Blog Post of the Year. Of course, this is the Year of Duck Sex, so it is not surprising that the Blog Post of the Year is on this exciting topic, Ed’s Ballistic penises and corkscrew vaginas – the sexual battles of ducks.
I won something, too. I felt I had a chance in the category of Research Twitterer of the Year – an lo and behold: I won in this category! Or, as Michael Robinson said on Twitter, this title should be better called “Esteemed Twitterary Figure” 😉
I was also nominated in the category of Best Blog — Biology, but did not believe I could win it in company of some wonderful bloggers who write posts about peer-reviewed research much more often than I do. But I guess the community thought that when I do write, I write well, so I found myself surprised winning in this category as well. This definitely motivates me to do more of this…and I have already assembled a nice little pile of recent papers to blog about very soon.
Thank you all for your support. And big Congratulations to all the winners and finalists, all great bloggers worth your regular daily reading. And if you blog about scientific papers and are not aggregating your posts on ResearchBlogging.org yet, perhaps it’s time to apply today.
Update: Read this great interview with Ed Yong about Life, Universe and Blogging (because Blogging IS Everything Else)

New and Exciting in PLoS ONE

There are 27 new articles in PLoS ONE today. As always, you should rate the articles, post notes and comments and send trackbacks when you blog about the papers. You can now also easily place articles on various social services (CiteULike, Mendeley, Connotea, Stumbleupon, Facebook and Digg) with just one click. Here are my own picks for the week – you go and look for your own favourites:
A New Basal Sauropodomorph Dinosaur from the Lower Jurassic Navajo Sandstone of Southern Utah:

Basal sauropodomorphs, or ‘prosauropods,’ are a globally widespread paraphyletic assemblage of terrestrial herbivorous dinosaurs from the Late Triassic and Early Jurassic. In contrast to several other landmasses, the North American record of sauropodomorphs during this time interval remains sparse, limited to Early Jurassic occurrences of a single well-known taxon from eastern North America and several fragmentary specimens from western North America. On the basis of a partial skeleton, we describe here a new basal sauropodomorph dinosaur from the Lower Jurassic Navajo Sandstone of southern Utah, Seitaad ruessi gen. et sp. nov. The partially articulated skeleton of Seitaad was likely buried post-mortem in the base of a collapsed dune foreset. The new taxon is characterized by a plate-like medial process of the scapula, a prominent proximal expansion of the deltopectoral crest of the humerus, a strongly inclined distal articular surface of the radius, and a proximally and laterally hypertrophied proximal metacarpal I. Phylogenetic analysis recovers Seitaad as a derived basal sauropodomorph closely related to plateosaurid or massospondylid ‘prosauropods’ and its presence in western North America is not unexpected for a member of this highly cosmopolitan clade. This occurrence represents one of the most complete vertebrate body fossil specimens yet recovered from the Navajo Sandstone and one of the few basal sauropodomorph taxa currently known from North America.

The Number of Cultural Traits Is Correlated with Female Group Size but Not with Male Group Size in Chimpanzee Communities:

What determines the number of cultural traits present in chimpanzee (Pan troglodytes) communities is poorly understood. In humans, theoretical models suggest that the frequency of cultural traits can be predicted by population size. In chimpanzees, however, females seem to have a particularly important role as cultural carriers. Female chimpanzees use tools more frequently than males. They also spend more time with their young, skewing the infants’ potential for social learning towards their mothers. In Gombe, termite fishing has been shown to be transmitted from mother to offspring. Lastly, it is female chimpanzees that transfer between communities and thus have the possibility of bringing in novel cultural traits from other communities. From these observations we predicted that females are more important cultural carriers than males. Here we show that the reported number of cultural traits in chimpanzee communities correlates with the number of females in chimpanzee communities, but not with the number of males. Hence, our results suggest that females are the carriers of chimpanzee culture.

Captive Housing during Water Vole (Arvicola terrestris) Reintroduction: Does Short-Term Social Stress Impact on Animal Welfare?:

Animals captive bred for reintroduction are often housed under conditions which are not representative of their preferred social structure for at least part of the reintroduction process. Specifically, this is most likely to occur during the final stages of the release programme, whilst being housed during transportation to the release site. The degree of social stress experienced by individuals during this time may negatively impact upon their immunocompetence. We examined two measure of stress – body weight and Leukocyte Coping Capacity (LCC) – to investigate the effects of group size upon captive-bred water voles destined for release within a reintroduction program. Water voles were housed in laboratory cages containing between one and eight individuals. LCC scores were negatively correlated with group size, suggesting that individuals in larger groups experienced a larger degree of immuno-suppression than did individuals housed in smaller groups or individually. During the course of the study mean body weights increased, in contrast to expectations from a previous study. This was attributed to the individuals sampled being sub-adults and thus growing in length and weight during the course of the investigation. The reintroduction process will inevitably cause some stress to the release cohort. However, for water voles we conclude that the stress experienced may be reduced by decreasing group size within captive colony and/or transportation housing practises. These findings are of significance to other species’ reintroductions, in highlighting the need to consider life-history strategies when choosing housing systems for animals being maintained in captivity prior to release to the wild. A reduction in stress experienced at the pre-release stage may improve immunocompetence and thus animal welfare and initial survival post-release.

The Unbearable Lightness of Health Science Reporting: A Week Examining Italian Print Media:

Although being an important source of science news information to the public, print news media have often been criticized in their credibility. Health-related content of press media articles has been examined by many studies underlining that information about benefits, risks and costs are often incomplete or inadequate and financial conflicts of interest are rarely reported. However, these studies have focused their analysis on very selected science articles. The present research aimed at adopting a wider explorative approach, by analysing all types of health science information appearing on the Italian national press in one-week period. Moreover, we attempted to score the balance of the articles. We collected 146 health science communication articles defined as articles aiming at improving the reader’s knowledge on health from a scientific perspective. Articles were evaluated by 3 independent physicians with respect to different divulgation parameters: benefits, costs, risks, sources of information, disclosure of financial conflicts of interest and balance. Balance was evaluated with regard to exaggerated or non correct claims. The selected articles appeared on 41 Italian national daily newspapers and 41 weekly magazines, representing 89% of national circulation copies: 97 articles (66%) covered common medical treatments or basic scientific research and 49 (34%) were about new medical treatments, procedures, tests or products. We found that only 6/49 (12%) articles on new treatments, procedures, tests or products mentioned costs or risks to patients. Moreover, benefits were always maximized and in 16/49 cases (33%) they were presented in relative rather than absolute terms. The majority of stories (133/146, 91%) did not report any financial conflict of interest. Among these, 15 were shown to underreport them (15/146, 9.5%), as we demonstrated that conflicts of interest did actually exist. Unbalanced articles were 27/146 (18%). Specifically, the probability of unbalanced reporting was significantly increased in stories about a new treatment, procedure, test or product (22/49, 45%), compared to stories covering common treatments or basic scientific research (5/97, 5%) (risk ratio, 8.72). Consistent with prior research on health science communication in other countries, we report undisclosed costs and risks, emphasized benefits, unrevealed financial conflicts of interest and exaggerated claims in Italian print media. In addition, we show that the risk for a story about a new medical approach to be unbalanced is almost 9 times higher with respect to stories about any other kind of health science-related topics. These findings raise again the fundamental issue whether popular media is detrimental rather than useful to public health.

Differential Expression of the Circadian Clock in Maternal and Embryonic Tissues of Mice:

Molecular feedback loops involving transcription and translation and several key genes are at the core of circadian regulatory cycles affecting cellular pathways and metabolism. These cycles are active in most adult animal cells but little is known about their expression or influence during development. To determine if circadian cycles are active during mammalian development we measured the expression of key circadian genes during embryogenesis in mice using quantitative real-time RT-PCR. All of the genes examined were expressed in whole embryos beginning at the earliest age examined, embryonic day 10. In contrast to adult tissues, circadian variation was absent for all genes at all of the embryonic ages examined in either whole embryos or individual tissues. Using a bioluminescent fusion protein that tracks translation of the circadian gene, per2, we also analyzed protein levels. Similar to mRNA, a protein rhythm was observed in adult tissue but not in embryonic tissues collected in-vivo. In contrast, when tissues were placed in culture for the continuous assay of bioluminescence, rhythms were observed in embryonic (E18) tissues. We found that placing embryonic tissues in culture set the timing (phase) of these rhythms, suggesting the importance of a synchronizing signal for the expression of circadian cycles in developing tissues. These results show that embryonic tissues express key circadian genes and have the capacity to express active circadian regulatory cycles. In vivo, circadian cycles are not expressed in embryonic tissues as they are in adult tissues. Individual cells might express oscillations, but are not synchronized until later in development.

Citability of Original Research and Reviews in Journals and Their Sponsored Supplements:

The contents of pharmaceutical industry sponsored supplements to medical journals are perceived to be less credible than the contents of their parent journals. It is unknown if their contents are cited as often. The objective of this study was to quantify the citability of original research and reviews contained in supplements and compare it with that for the parent journal. This was a cohort study of 446 articles published in the Journal of Clinical Psychiatry (JCP) and its supplements for calendar years 2000 and 2005. The total citation counts for each article up to October 5, 2009 were retrieved from the ISI Web of Science database. The main outcome measure was the number of citations received by an article since publication. Regular journal articles included 114 from calendar year 2000 and 190 from 2005. Articles from supplements included 90 from 2000 and 52 from 2005. The median citation counts for the 3 years post-publication were 10 (interquartile range [IQR], 4-20), 14 (IQR, 8-20), 13.5 (IQR, 8-23), and 13.5 (IQR, 8-20), for the 2000 parent journal, 2000 supplements, 2005 parent journal, and 2005 supplements, respectively. Citation counts were higher for the articles in the supplements than the parent journal for the cohorts from 2000 (p = .02), and no different for the year 2005 cohorts (p = .88). The 2005 parent journal cohort had higher citation counts than the 2000 cohort (p = .007), in contrast to the supplements where citation counts remained the same (p = .94). Articles published in JCP supplements are robustly cited and thus can be influential in guiding clinical and research practice, as well as shaping critical thinking. Because they are printed under the sponsorship of commercial interests, they may be perceived as less than objective. A reasonable step to help improve this perception would be to ensure that supplements are peer-reviewed in the same way as regular articles in the parent journal.

Clock Quotes

When asked, “How do you write?” I invariably answer, “one word at a time.”
– Stephen King

Welcome the newest SciBling!

Wow! I often get the vibes and hints in the background and through the grapevine when the Borg is about to swallow yet another unsuspecting science blogger. But this took me totally by surprise! And it could not have happened to a worthier blogger. Go say Hello to Christie Wilcox who just moved her delicious blog Observations Of A Nerd from here to its new digs here. Welcome to the Family! (you can check out any time you like, but you can never leave….)

ScienceOnline2010 – interview with Diana Gitig

Continuing with the tradition from last two years, I will occasionally post interviews with some of the participants of the ScienceOnline2010 conference that was held in the Research Triangle Park, NC back in January. See all the interviews in this series here. You can check out previous years’ interviews as well: 2008 and 2009.
Today, I asked Diana Gitig to answer a few questions.
Welcome to A Blog Around The Clock. Would you, please, tell my readers a little bit more about yourself? Where are you coming from (both geographically and philosophically)? What is your (scientific) background?
Diane Gitig pic.jpgI live in White Plains, a suburb of New York. I have a Ph.D. in cell biology but was not particularly well suited to lab work. My thesis advisor suggested that writing might better play to my strengths. I had my first baby the week after I defended my thesis, and I have been writing on a freelance basis since then. I was pretty much doing the stay-at-home mom thing, writing when the babies were sleeping for my own mental stimulation and to try to keep my foot in the door. I am very grateful to the feminist movement (and my husband’s salary) because I always knew that my staying at home was a choice, not a given; any day I woke up and decided I wanted to get a job, I could try to do so. I very much enjoyed being home with my little ones, but I view it as just one chapter in my life, and it is ending now that my youngest went off to school in September. This precipitated a minor identity crisis: I really thought about how I perceive myself, and not just what do I want to do but who do I want to be? After much introspection I decided to try to be a full time freelance science writer.
Tell us a little more about your career trajectory so far: interesting projects past and present?
Somewhat ironically, I have fallen into this niche of writing about laboratory techniques – the very methods at which I did not excel in graduate school. My favorite assignments were reviewing science and science fiction books as a freelance editor at amazon, since I actually like reading more than I like writing, and a couple of articles I wrote for Science. I know it is not at all like having a Science paper, but it is somewhat thrilling to be published there just the same. Covering symposia at the New York Academy of Sciences was also fun, as I got to get out and meet interesting people but still do the bulk of the work on my own time.
What is taking up the most of your time and passion these days? What are your goals?
Honestly, efficient scheduling is a big challenge for me these days – I am very happy to have a number of assignments, but time management is a skill I have not used in a while and have to relearn. My goals are to keep busy and learn cool stuff. So far, so good.
Do you find all this online activity to be a net positive (or even a necessity) in what you do?
Online activity is essential in what I do. I literally could not have this career and this life without it. I work with editors and interview scientists and entrepreneurs all over the world, and I cannot imagine doing so without the ability to send work back and forth instantly. Having access to papers at home is invaluable. The ability to work alone and at home can obviously have a downside too, but Twitter takes care of that by helping me feel connected.
Have you discovered any cool science blogs by the participants at the Conference?
I was really impressed by Ed Yong, so I read his stuff now. I enjoyed talking to Jonathan Eisen, so I look at his now too. And yours of course. I also made some contacts that have enabled me to contribute to some blog-like sites, which has been great.
What was the best aspect of ScienceOnline2010 for you?
For sure the Mexican chocolate Locopops.
But in terms of content, I really, really loved Michael Specter’s address on Friday night. It totally resonated with me. He spoke about a lot of things I had been thinking about, but he verbalized them much more clearly than I had.
It was so nice to meet you in person and thank you for the interview. I hope to see you again next January.
You too! And in NY for the 140 conference!

On organizing and/or participating in a Conference in the age of Twitter

This is the first time ever that I cared about SXSW conference or was jealous for not being there. Watching the blogs and Twitter stream, it appears to have been better and more exciting than ever. I guess I’ll have to figure out a way to finally get myself there next year….
But this post is not really about SXSW. It is about presenting at such conferences. More specifically, how the back-channel (on Twitter and elsewhere) affects the way one needs to approach an invitation to speak at meetings where much of the audience is highly wired online: to say Yes or No to the invitation in the first place, and if Yes how to prepare and how to conduct oneself during the presentation.
A great example of this was the Future of Context panel at SXSW, with Jay Rosen, Matt Thompson and Tristan Harris, moderated by Staci Kramer.
After the meeting ended, Jay Rosen described in great detail all the things they did to prepare for the session and how that all worked – go and read: How the Backchannel Has Changed the Game for Conference Panelists. I will be sending the link to that post to all the speakers/panelists/presenters/moderators at ScienceOnline2011 once the program is set. That is definitely a post to bookmark and save if you are organizing a conference, or if you are ever invited to speak at one.
This includes people who tend to speak at conferences that are not filled to the brim with the Twitterati. Even at such conferences, a small but loud proportion of your audience WILL tweet. Be prepared! Even if you are speaking at the AAAS meeting.
There are other important things to think about – both for organizers and presenters.
First, public speaking is for some people the most terrifying thing they can ever be asked to do. But even those who are not completely terrified, may need some training in order to do well. Have new people be mentored by experienced speakers (I mentioned how we do that at ScienceOnline at the end of this post) by sharing the panel. As an organizer, work hard to help the new speakers to alleviate their fears, to make crystal-clear what is expected of them, to provide them support before, during and after their sessions.
Many organizers are hoping to increase diversity (of personal experiences and approaches, not just in terms of gender, race, age, ethnicity and such, though the diversity in the latter usually brings along the diversity in the former as well). They need to remember that announcing this intent is not enough. People who were not welcome at the table before have no reason to believe that they will be welcome now – so why bother. You have to do more – actively reach out and engage them. And, as your conference (like ScienceOnline) goes through years, if you are successful at bringing in the diverse groups to the table – they will notice. They will invite others to come next year. The meeting gains reputation, over the years, for being open and inclusive (nobody is a superstar and everybody is a superstar). Instead of being tokens, they become an integral part of the conference and help shape it. This takes work.
Second, the Back-channel should never become the Front-channel!!!! Never display tweets on the screen behind the speaker. Never. On the other hand, please make it easy for the speakers to monitor the Twitterverse on their own computer screens if they want to.
Third, if you are organizing a conference, think hard about the format. At a typical scientific conference, the speaker is a scientist who is presenting new data. The talk is likely to have a level of complexity (as well as an arrow of the narrative) that is not served well by constant interruption. In such cases, a traditional format, with a Q&A period (long enough!) at the end is just fine. TED and TEDx conferences are similar. Quick presentations, like Ignite or storytelling events are similar – the presentations are too short and too well-rehearsed to be able to withstand interruptions. But you have to have a Q&A at the end – it is irresponsible not to have it.
For example, many sessions at the AAAS meeting are three hours long! Including my session. And in each one of those that I attended, the moderator announced at the beginning that the Q&A will be at the end. Hmmm, how many people will still be in the room after 2 hours and 40 minutes? They will be either long gone, or brain-dead and eager to leave. So we tried to do the best we could with the format we had – we had 2-3 people ask questions after each one of our presentations (there were six of us at the panel) as well as at the very end. And you know what – at the end of the third hour, the room was still full and we were still getting more questions. Engaging the audience early on got them excited. They wanted to stay in the room and engage some more, 2-3 of them every 20 minutes or so, and several more at the end.
On the other end of the spectrum to the one-to-many lecture is a fully-fledged Unconference format. It is based on the insight that “The sum of the expertise of the people in the audience is greater than the sum of expertise of the people on stage.“. This, of course, depends on the topic, the speaker, and the audience.
As I explained at length in this post after ScienceOnline’09, and at even more length in this radio interview after ScienceOnline2010, our inaugural meeting in 2007 was a pure Unconference, but that we since decided to move to a hybrid format for a number of reasons I explained in both of these places.
Think, for example, of Workshops. We had a Blogging101 workshop at a different day, time and place in 07 and 08. We expanded the number of workshops in 2009 and had them as a part of the main program (just tagged as workshops), and then in 2010 we again moved them all to a different day, time and space to make it clear that these sessions are different – not Unconference-y in format, and for a good reason (we’ll do the same next year).
A Blogging101 workshop, for example, will have an experience blogger at the front. The audience will be full of people who have never blogged and want to learn how. The moderator is an expert, and acts as a teacher or trainer or ‘fount of wisdom’ to the audience who came to get exactly that – instruction. The audience expects to learn how to start a blog, how to post the first introductory post, how to make a link and insert a picture, how to build a blogroll and change the visual design of the blog from an existing set of choices. They also expect some sage advice on what is regarded as proper blogging behavior so they do not get instantly slammed when they enter the blogosphere for “doing it wrong”. The kinds of questions such an audience asks are going to be calls for help and clarification, perhaps for more information. They are unlikely to insert their own opinions and information, or to challenge the session leader. It is more of a classroom lecture (or lab) than a freewheeling discussion. Yet is has its own usefulness and should not be looked down upon because it is not in an Unconference format.
Actually, a Blogging102 workshop, where the audience already has some experience in blogging and is looking for tips and tricks for making their blogs better, looking better, and promoted better, there will be additional insights from the audience – which we saw at Scio10: that workshop was quite participatory and interactive.
Then, there are demos. A demo is just 12 minutes long with additional 3 minutes reserved for Q&A. The presenter is showing off his/her website or software or what-not to people who have not seen it before and would like to see how it works. Again, interruption of such a short and carefully prepared presentation would not be a good thing. If you have more to discuss – grab the presenter in the hallway afterwards. We are thinking of moving the Demos (both 12-minute presentations and potentially stations or booths) to a different day/time/space next year as well. Nothing wrong with that format, but it is not in an Unconference spirit.
Yet, the bulk of our conference is an Unconference. And we have seen that well-prepared presenters can turn even large 4-5 person panels into lively discussions off the bat. I have described one such 2009 panel in this post and there were several this year (most notably the Rebooting Science Journalism session). What we tell both moderators and participants is that the name of the session is not a title of a lecture but the topic of the conversation for that hour.
People who already have experience with the unconference format lead the way (we try to have such people lead the first morning sessions to set the tone for the rest of the event) and n00bs follow. Once everyone is in the swing of things and participating freely, it is easy to have a session be very informal. For example, last year Pete Binfield and Henry Gee started off their session with the question “Our topic is “A” – what do you want to talk about?”. And that worked brilliantly as people who decided to attend that particular session already had questions and comments prepared in their minds and were ready to start discussing the topic right from the start. Other sessions require more of an intro, and that is OK as well.
So, the bottom line is that there is a spectrum of potential formats and each format has its pros and cons. The duration (from 5 minutes to 3 hours and everything in-between) will dictate how participatory the session can be. The relative difference between the expertise of the people on stage and the people in the audience is also a factor – more even they are, more participatory the session should be. As an organizer, always strive to have the sessions as participatory as the format/topic/people allows it, not less. Having less will diminish the experience – it will be seen as preaching down and trust will be lost.
And keep the Back-channel in mind – people in the room are not the only people participating. Make sure that the people following on Twitter, or Ustream or SecondLife can participate to some extent as well – perhaps let the people/audience in the room (all of them or a few chosen individuals) be moderators of Twitter chatter, and ask the cameraman to introduce questions from the Ustream audience into the room. We did both at ScienceOnline2010 and the feedback from virtual audience was positive. We’ll try to do even better next year.

America’s Science Challenges and Opportunities: Past, Present and Future

This is a part of Scope Academy 2010 at NCSU (click to see the rest of the program and to register):

SAS Hall, North Campus, April 10th, 4:00 pm
Scope/Harrelson Lecture
Keynote speaker Neal Lane, Malcolm Gillis University Professor at Rice University and senior fellow of the James A. Baker III Institute for Public Policy, presents:
America’s Science Challenges and Opportunities: Past, Present and Future
The United States, especially since World War II, has been powered by science, engineering and technology. The rationale for the federal government’s large investment in research was originally WWII and the cold war that followed. But in recent decades the emphasis has shifted to health and medicine and, more recently, energy, technological innovation and the economy. This talk will review a bit of the history, describe some current challenges and opportunities and offer speculation on possible futures for American science and implications for the nation.

I will probably go to this and blog about it later.

Clock Quotes

Lots of times you have to pretend to join a parade in which you’re not really interested in order to get where you’re going.
– Christopher Morley

ScienceOnline2010 – interview with Ivan Oransky

Continuing with the tradition from last two years, I will occasionally post interviews with some of the participants of the ScienceOnline2010 conference that was held in the Research Triangle Park, NC back in January. See all the interviews in this series here. You can check out previous years’ interviews as well: 2008 and 2009.
Today, I asked Ivan Oransky from Reuters Health and Embargo Watch to answer a few questions.
Welcome to A Blog Around The Clock. Would you, please, tell my readers a little bit more about yourself? Where are you coming from (both geographically and philosophically)? What is your (scientific) background?
I grew up in the New York suburbs. I earned a bachelor’s in biology, then trained as an MD, and got through a year of psychiatry residency before leaving medicine to be a full-time journalist. Along the way, I spent four summers and some other time working in basic science labs, studying the complement system and pediatric infectious diseases. Today, I’m the executive editor of Reuters Health, based in New York, where I live in the less and less appropriately named neighborhood of Hell’s Kitchen. My wife and I split time between there and western Massachusetts.
Tell us a little more about your career trajectory so far: interesting projects past and present?
Ivan Oransky pic.jpgI left medicine in 1999, but I had been committing journalism since I set foot in the Harvard Crimson as a freshman in 1990. (Or perhaps more accurately, since I joined my high school paper in 1986.) I eventually edited the Crimson’s science and health coverage, and became executive editor. In medical school, I edited the medical student section of JAMA, and wrote for other outlets including the Baltimore Sun, The New Republic, and U.S. News and World Report. During my first year of residency, American Medical News was kind enough to give me a column, which a Yale dean made a point of saying embarrassed him in a letter to all of my clinical supervisors. Around that time, I also started a weekly column for The Forward, a weekly Jewish newspaper, called The Doctor. If there’s a health problem Jews don’t worry about, it’s news to me, so I had plenty of material. Between then and now I’ve written for a number of other publications, from The Boston Globe to Salon to Slate to the Wall Street Journal Online. I’ve also co-authored books including The Common Symptom Answer Guide.
My first full-time journalism job, starting in May 2000, was as editor in chief of Praxis Post, a webzine of medicine and culture. We had a great time and earned important recognition, including being named a finalist for the 2001 Online News Association Award for General Excellence, but soon sadly went the way of the dot-com boom. In 2002, I became web editorial director of The Scientist, and I was promoted to deputy editor of the magazine in 2004, overseeing web as well as print. We won a slew of awards while I was there, including the Magazine of the Year Award from the American Society of Business Publication Editors. I left The Scientist in March 2008 to become managing editor of online at Scientific American, where we grew traffic by 50%. I left SciAm in June 2009 to take my current position as executive editor of Reuters Health.
Throughout my decade of editorial management, I’ve had the good fortune to have smarter and more talented people than me willing to be part of my staff. Learning from them, and working with them to implement our joint visions, has more than made up for the fact that I really don’t have the time to do much of my own writing anymore. I’ve also benefited from generous and brilliant mentors such as former JAMA editor-in-chief George Lundberg.
What is taking up the most of your time and passion these days? What are your goals?
My day job takes up most of my time, as well as my mental energy. It’s a challenging time to be in journalism, as A Blog Around The Clock readers know, so just keeping up — and improving — the high standards of Reuters Health, while experimenting with new journalistic forms, is a full-time job. But my work at Reuters goes hand-in-hand with my three other passions: the Association of Health Care Journalists, where I’m treasurer; New York University’s Science, Health, and Environmental Reporting Program, where I’ve taught medical journalism for eight years and have served as faculty advisor to Scienceline for four; and my new blog, Embargo Watch.
My goal in all of that work is to help people commit better journalism. Some of those people are full-time journalists. Some may be training to become full-time journalists, and some may not be employed as journalists at all. But if they’re writing for me, a student of mine, an AHCJ member, or reading and commenting on my blog, to me they’re part of ensuring the future of journalistic ideals — independence, accountability, and accuracy, to name a few.
Then, of course, there are the New York Yankees, whose season is about to get started as I write this. Which means I’ll be on the subway up to my season tickets in the bleachers as often as possible…
How does (if it does) blogging figure in your work? How about social networks, e.g., Twitter, FriendFeed and Facebook? Do you find all this online activity to be a net positive (or even a necessity) in what you do?
Although I contributed to the news blogs at The Scientist and Scientific American, I’ve just started my first personal blog, Embargo Watch, whose tagline is “keeping an eye on how scientific information embargoes affect news coverage.” I’m an active Twitter and Facebook user. I’m not on Friendfeed at the moment. I am squarely in the necessity camp when it comes to this stuff. I learn something whenever our audience comments on, retweets, criticizes, or ignores what we’ve put out there. And the story tips — for Reuters Health as well as for Embargo Watch — are invaluable.
What was the best aspect of ScienceOnline2010 for you? Any suggestions for next year? Is there anything that happened at this Conference – a session, something someone said or did or wrote – that will change the way you think about science communication, or something that you will take with you to your job, blog-reading and blog-writing?
ScienceOnline sessions are always great, of course, but for me the highlights of ScienceOnline2010 were, as always, the gathering of the best minds in science blogging, all of whom are available for passionate chats in the hallways and the bar. I’m not sure I can point to anything in particular, but rather to the whole experience, as spurring me to start Embargo Watch. Getting invited to guest blog by the wonderful Ed Yong, whom I met for the first time at ScienceOnline2010, was important inspiration, as was knowing I can count on the other people I met for support and guidance. This year, the cabal — and I use that term with love — of book authors I hung out with has also encouraged me to think about a book I want to write.
I look forward to ScienceOnline2011, 2012, and on and on. Having been to all four of them now, I can say confidently that they keep getting better. My one suggestion for 2011 and beyond is to pay attention to the potential pitfalls of ScienceOnline’s success. It’s already become a place a lot of people want to be, and its audience one that a lot of interests want to engage. That’s a good thing. But it also means that the participants need to think carefully about conflicts of interest, funding sources, and that sort of thing. An example: Carl Zimmer and I turned to one another during the last after-dinner Ignite Talk this year and wondered, at the same moment, whom the speaker’s clients were. I think the speaker was happy to tell us, but that was the sort of thing that should have been baked into a disclosure in his talk. Setting ground rules like that ahead of time will only help ScienceOnline grow and mature even more than it already has. But this isn’t a criticism — I’m just speaking from experience as someone who has been on the board of directors of a group that’s only turning 12 this year.
It was so nice to see you again – the fourth time! – and thank you for the interview. I hope to see you again next January.

The 2010 North Carolina Science and Engineering Fair

The 2010 North Carolina Science and Engineering Fair will be held at Meredith College in Raleigh on March 26th-27th. You can see the details here. The part that is open to public will be on Saturday March 27th from 2:30 – 4:00 pm.
From the NC Science, Mathematics, and Technology Education Center:

Young scientists from across the state will gather at Meredith College in Raleigh on Sat., March 27, to participate in the N.C. Science and Engineering Fair (NCSEF). Students from 3rd grade through 12th grade will present original science and engineering research. NCSEF showcases the highest level of student achievement in the state.
Students competing in the NCSEF were selected from last month’s 10 regional competitions. Advancing to the state competition are 250 student research projects. The student projects will be available for public viewing from 2:30 and 4 p.m. in the Science and Math Building and Harris Hall on Meredith’s campus.
“In today’s global economy, science, mathematics and technology are cornerstones of many countries’ economic development strategy. It is imperative that we establish a passion in our youth for science and math,” said Sam Houston, president and CEO of the North Carolina Science, Mathematics, and Technology Education Center (SMT Center). “The North Carolina Science and Engineering Fair is designed to actively engage students in science and technology, and practice the adult skills of not only finding answers, but explaining them to others.”
The SMT Center’s support for science competitions includes recruiting and providing training for scientists and engineers to serve as judges at the State Science and Engineering Fair as well as local and regional fairs. According to Dr. Houston, science competitions such as the NCSEF can be an outlet for students to showcase scientific research they have conducted for high school graduation projects and other external student and community science initiatives.
Students will have opportunities to compete for financial awards and the opportunity to present at two prestigious international student research competitions, among other special awards this year according to Judy Day, assistant director, Office of Undergraduate Research at North Carolina State University, and the NCSEF volunteer director.
Outstanding projects from 5th – 8th grade students will be nominated for the Discovery Education Young Scientist Challenge. Selected high school students will go on to the INTEL International Science and Engineering Fair that will take place in May in San Jose, California, to display their research with 1,500 students from 40 countries. This year, two middle school projects and two high school projects will be selected to represent NCSEF at the International Sustainable World (Energy, Engineering & Environment) Project (ISWEEEP) in Houston, Tex.
Current NCSEF corporate and university sponsors include:
• GlaxoSmithKline
• Time Warner Cable: Connect A Million Minds
• Burroughs Wellcome Fund
• NC Science, Mathematics, and Technology Education Center
• Duke Energy
• Strategic Educational Alliances
• BlueCross BlueShield of North Carolina
• Meredith College
• North Carolina State University

I’ll try to make it to the portion that is open to the public and blog about it afterwards.

Rebecca Skloot is in the Triangle, NC

My SciBling Rebecca Skloot will be here in the Triangle for a couple of days this week promoting her book The Immortal Life of Henrietta Lacks. I’ll be out of town for most of this (off to Boston in a couple of hours), but you should come to one or more of these events if you can:
Monday night 3/22, 7:30 pm she’ll be at Quail Ridge Books in Raleigh just off the Wade Ave exit on I-40:
Tuesday 3/23, noon, she’ll be Frank Stasio’s guest on The State of Things at WUNC-FM 91.5
Tuesday 3/23, 3 pm, she’ll be the keynote speaker of a mini-symposium on African American issues in science, medicine, and history at North Carolina Central University. Blair Kelley from NC State’s History Dept will speak at 3 pm, Dr.David Kroll will give a talk at 3:30 on the HeLa cell production unit set up in the mid-1950s at Tuskegee University by the March of Dimes, then Rebecca will give her book talk at 4 pm, followed by a book signing. The talk will be in the auditorium of the BBRI (Biomedical Biotechnology Research Institute) on George Street on the east side of Fayetteville St.
Wednesday night, 3/24, 5:30 pm, she’ll give the Crown Lecture on Ethics at Duke’s Sanford Institute
Follow Rebecca on her blog and Twitter.

The new issue of Journal of Science Communication is now published

The new issue of Journal of Science Communication is now online (Open Access, so you can download all PDFs for free). Apart from the article on blogging that we already dissected at length, this issue has a number of interesting articles, reviews, perspectives and papers:
Users and peers. From citizen science to P2P science:

This introduction presents the essays belonging to the JCOM special issue on User-led and peer-to-peer science. It also draws a first map of the main problems we need to investigate when we face this new and emerging phenomenon. Web tools are enacting and facilitating new ways for lay people to interact with scientists or to cooperate with each other, but cultural and political changes are also at play. What happens to expertise, knowledge production and relations between scientific institutions and society when lay people or non-scientists go online and engage in scientific activities? From science blogging and social networks to garage biology and open tools for user-led research, P2P science challenges many assumptions about public participation in scientific knowledge production. And it calls for a radical and perhaps new kind of openness of scientific practices towards society.

Changing the meaning of peer-to-peer? Exploring online comment spaces as sites of negotiated expertise:

This study examines the nature of peer-to-peer interactions in public online comment spaces. From a theoretical perspective of boundary-work and expertise, the comments posted in response to three health sciences news articles from a national newspaper are explored to determine whether both scientific and personal expertise are recognized and taken up in discussion. Posts were analysed for both explicit claims to expertise and implicit claims embedded in discourse. The analysis suggests that while both scientific and personal expertise are proffered by commenters, it is scientific expertise that is privileged. Those expressing scientific expertise receive greater recognition of the value of their posts. Contributors seeking to share personal expertise are found to engage in scientisation to position themselves as worthwhile experts. Findings suggest that despite the possibilities afforded by online comments for a broader vision of what peer-to-peer interaction means, this possibility is not realized.

The public production and sharing of medical information. An Australian perspective:

There is a wealth of medical information now available to the public through various sources that are not necessarily controlled by medical or healthcare professionals. In Australia there has been a strong movement in the health consumer arena of consumer-led sharing and production of medical information and in healthcare decision-making. This has led to empowerment of the public as well as increased knowledge-sharing. There are some successful initiatives and strategies on consumer- and public-led sharing of medical information, including the formation of specialised consumer groups, independent medical information organisations, consumer peer tutoring, and email lists and consumer networking events. With well-organised public initiatives and networks, there tends to be fairly balanced information being shared. However, there needs to be caution about the use of publicly available scientific information to further the agenda of special-interest groups and lobbying groups to advance often biased and unproven opinions or for scaremongering. With the adoption of more accountability of medical research, and the increased public scrutiny of private and public research, the validity and quality of medical information reaching the public is achieving higher standards.

Social network science: pedagogy, dialogue, deliberation:

The online world constitutes an ever-expanding store and incubator for scientific information. It is also a social space where forms of creative interaction engender new ways of approaching science. Critically, the web is not only a repository of knowledge but a means with which to experience, interact and even supplement this bank. Social Network Sites are a key feature of such activity. This paper explores the potential for Social Network Sites (SNS) as an innovative pedagogical tool that precipitate the ‘incidental learner’. I suggest that these online spaces, characterised by informality, open-access, user input and widespread popularity, offer a potentially indispensable means of furthering the public understanding of science; and significantly one that is rooted in dialogue.

Open science: policy implications for the evolving phenomenon of user-led scientific innovation:

From contributions of astronomy data and DNA sequences to disease treatment research, scientific activity by non-scientists is a real and emergent phenomenon, and raising policy questions. This involvement in science can be understood as an issue of access to publications, code, and data that facilitates public engagement in the research process, thus appropriate policy to support the associated welfare enhancing benefits is essential. Current legal barriers to citizen participation can be alleviated by scientists’ use of the “Reproducible Research Standard,” thus making the literature, data, and code associated with scientific results accessible. The enterprise of science is undergoing deep and fundamental changes, particularly in how scientists obtain results and share their work: the promise of open research dissemination held by the Internet is gradually being fulfilled by scientists. Contributions to science from beyond the ivory tower are forcing a rethinking of traditional models of knowledge generation, evaluation, and communication. The notion of a scientific “peer” is blurred with the advent of lay contributions to science raising questions regarding the concepts of peer-review and recognition. New collaborative models are emerging around both open scientific software and the generation of scientific discoveries that bear a similarity to open innovation models in other settings. Public engagement in science can be understood as an issue of access to knowledge for public involvement in the research process, facilitated by appropriate policy to support the welfare enhancing benefits deriving from citizen-science.

Googling your genes: personal genomics and the discourse of citizen bioscience in the network age:

In this essay, I argue that the rise of personal genomics is technologically, economically, and most importantly, discursively tied to the rise of network subjectivity, an imperative of which is an understanding of self as always already a subject in the network. I illustrate how personal genomics takes full advantage of social media technology and network subjectivity to advertise a new way of doing research that emphasizes collaboration between researchers and its members. Sharing one’s genetic information is considered to be an act of citizenship, precisely because it is good for the network. Here members are encouraged to think of themselves as dividuals, or nodes, in the network and their actions acquire value based on that imperative. Therefore, citizen bioscience is intricately tied, both in discourse and practices, to the growth of the network in the age of new media.

Special issue on peer-to-peer and user-led science: invited comments:

In this commentary, we collected three essays from authors coming from different perspectives. They analyse the problem of power, participation and cooperation in projects of production of scientific knowledge held by users or peers: persons who do not belong to the institutionalised scientific community. These contributions are intended to give a more political and critical point of view on the themes developed and analysed in the research articles of this JCOM special issue on Peer-to-peer and user-led science.
Michel Bauwens, Christopher Kelty and Mathieu O’Neil write about different aspects of P2P science. Nevertheless, the three worlds they delve into share the “aggressively active” attitude of the citizens who inhabit them. Those citizens claim to be part of the scientific process, and they use practices as heterogeneous as online peer-production of scientific knowledge, garage biology practiced with a hacker twist, or the crowdsourced creation of an encyclopedia page. All these claims and practices point to a problem in the current distribution of power. The relations between experts and non-experts are challenged by the rise of peer-to-peer science. Furthermore, the horizontal communities which live inside and outside the Net are not frictionless. Within peer-production mechanisms, the balance of power is an important issue which has to be carefully taken into account.

Is there something like a peer to peer science?:

How will peer to peer infrastructures, and the underlying intersubjective and ethical relational model that is implied by it, affect scientific practice? Are peer-to-peer forms of cooperation, based on open and free input of voluntary contributors, participatory processes of governance, and universal availability of the output, more productive than centralized alternatives? In this short introduction, Michel Bauwens reviews a number of open and free, participatory and commons oriented practices that are emerging in scientific research and practice, but which ultimately point to a more profound epistemological revolution linked to increased participatory consciousness between the scientist and his human, organic and inorganic research material.

Outlaw, hackers, victorian amateurs: diagnosing public participation in the life sciences today:

This essay reflects on three figures that can be used to make sense of the changing nature of public participation in the life sciences today: outlaws, hackers and Victorian gentlemen. Occasioned by a symposium held at UCLA (Outlaw Biology: Public Participation in the Age of Big Bio), the essay introduces several different modes of participation (DIY Bio, Bio Art, At home clinical genetics, patient advocacy and others) and makes three points: 1) that public participation is first a problem of legitimacy, not legality or safety; 2) that public participation is itself enabled by and thrives on the infrastructure of mainstream biology; and 3) that we need a new set of concepts (other than inside/outside) for describing the nature of public participation in biological research and innovation today.

Shirky and Sanger, or the costs of crowdsourcing:

Online knowledge production sites do not rely on isolated experts but on collaborative processes, on the wisdom of the group or “crowd”. Some authors have argued that it is possible to combine traditional or credentialled expertise with collective production; others believe that traditional expertise’s focus on correctness has been superseded by the affordances of digital networking, such as re-use and verifiability. This paper examines the costs of two kinds of “crowdsourced” encyclopedic projects: Citizendium, based on the work of credentialled and identified experts, faces a recruitment deficit; in contrast Wikipedia has proved wildly popular, but anti-credentialism and anonymity result in uncertainty, irresponsibility, the development of cliques and the growing importance of pseudo-legal competencies for conflict resolution. Finally the paper reflects on the wider social implications of focusing on what experts are rather than on what they are for.

The unsustainable Makers:

The Makers is the latest novel of the American science fiction writer, blogger and Silicon Valley intellectual Cory Doctorow. Set in the 2010s, the novel describes the possible impact of the present trend towards the migration of modes of production and organization that have emerged online into the sphere of material production. Called New Work, this movement is indebted to a new maker culture that attracts people into a kind of neo-artisan, high tech mode of production. The question is: can a corporate-funded New Work movement be sustainable? Doctorow seems to suggest that a capitalist economy of abundance is unsustainable because it tends to restrict the reach of its value flows to a privileged managerial elite.

New and Exciting in PLoS ONE

There are 32 new articles in PLoS ONE today. As always, you should rate the articles, post notes and comments and send trackbacks when you blog about the papers. You can now also easily place articles on various social services (CiteULike, Mendeley, Connotea, Stumbleupon, Facebook and Digg) with just one click. Here are my own picks for the week – you go and look for your own favourites:
Laetoli Footprints Preserve Earliest Direct Evidence of Human-Like Bipedal Biomechanics:

Debates over the evolution of hominin bipedalism, a defining human characteristic, revolve around whether early bipeds walked more like humans, with energetically efficient extended hind limbs, or more like apes with flexed hind limbs. The 3.6 million year old hominin footprints at Laetoli, Tanzania represent the earliest direct evidence of hominin bipedalism. Determining the kinematics of Laetoli hominins will allow us to understand whether selection acted to decrease energy costs of bipedalism by 3.6 Ma. Using an experimental design, we show that the Laetoli hominins walked with weight transfer most similar to the economical extended limb bipedalism of humans. Humans walked through a sand trackway using both extended limb bipedalism, and more flexed limb bipedalism. Footprint morphology from extended limb trials matches weight distribution patterns found in the Laetoli footprints. These results provide us with the earliest direct evidence of kinematically human-like bipedalism currently known, and show that extended limb bipedalism evolved long before the appearance of the genus Homo. Since extended-limb bipedalism is more energetically economical than ape-like bipedalism, energy expenditure was likely an important selection pressure on hominin bipeds by 3.6 Ma.

Embryonic, Larval, and Juvenile Development of the Sea Biscuit Clypeaster subdepressus (Echinodermata: Clypeasteroida):

Sea biscuits and sand dollars diverged from other irregular echinoids approximately 55 million years ago and rapidly dispersed to oceans worldwide. A series of morphological changes were associated with the occupation of sand beds such as flattening of the body, shortening of primary spines, multiplication of podia, and retention of the lantern of Aristotle into adulthood. To investigate the developmental basis of such morphological changes we documented the ontogeny of Clypeaster subdepressus. We obtained gametes from adult specimens by KCl injection and raised the embryos at 26C. Ciliated blastulae hatched 7.5 h after sperm entry. During gastrulation the archenteron elongated continuously while ectodermal red-pigmented cells migrated synchronously to the apical plate. Pluteus larvae began to feed in 3 d and were 20 d old at metamorphosis; starved larvae died 17 d after fertilization. Postlarval juveniles had neither mouth nor anus nor plates on the aboral side, except for the remnants of larval spicules, but their bilateral symmetry became evident after the resorption of larval tissues. Ossicles of the lantern were present and organized in 5 groups. Each group had 1 tooth, 2 demipyramids, and 2 epiphyses with a rotula in between. Early appendages consisted of 15 spines, 15 podia (2 types), and 5 sphaeridia. Podial types were distributed in accordance to Lovén’s rule and the first podium of each ambulacrum was not encircled by the skeleton. Seven days after metamorphosis juveniles began to feed by rasping sand grains with the lantern. Juveniles survived in laboratory cultures for 9 months and died with wide, a single open sphaeridium per ambulacrum, aboral anus, and no differentiated food grooves or petaloids. Tracking the morphogenesis of early juveniles is a necessary step to elucidate the developmental mechanisms of echinoid growth and important groundwork to clarify homologies between irregular urchins.

Emotion Separation Is Completed Early and It Depends on Visual Field Presentation:

It is now apparent that the visual system reacts to stimuli very fast, with many brain areas activated within 100 ms. It is, however, unclear how much detail is extracted about stimulus properties in the early stages of visual processing. Here, using magnetoencephalography we show that the visual system separates different facial expressions of emotion well within 100 ms after image onset, and that this separation is processed differently depending on where in the visual field the stimulus is presented. Seven right-handed males participated in a face affect recognition experiment in which they viewed happy, fearful and neutral faces. Blocks of images were shown either at the center or in one of the four quadrants of the visual field. For centrally presented faces, the emotions were separated fast, first in the right superior temporal sulcus (STS; 35-48 ms), followed by the right amygdala (57-64 ms) and medial pre-frontal cortex (83-96 ms). For faces presented in the periphery, the emotions were separated first in the ipsilateral amygdala and contralateral STS. We conclude that amygdala and STS likely play a different role in early visual processing, recruiting distinct neural networks for action: the amygdala alerts sub-cortical centers for appropriate autonomic system response for fight or flight decisions, while the STS facilitates more cognitive appraisal of situations and links appropriate cortical sites together. It is then likely that different problems may arise when either network fails to initiate or function properly.

Effect of Rhythmic Auditory Stimulation on Gait in Parkinsonian Patients with and without Freezing of Gait:

Freezing of gait (FOG) in Parkinson’s disease (PD) rises in prevalence when the effect of medications decays. It is known that auditory rhythmic stimulation improves gait in patients without FOG (PD-FOG), but its putative effect on patients with FOG (PD+FOG) at the end of dose has not been evaluated yet. This work evaluates the effect of auditory rhythmic stimulation on PD+FOG at the end of dose. 10 PD+FOG and 9 PD-FOG patients both at the end of dose periods, and 10 healthy controls were asked to perform several walking tasks. Tasks were performed in the presence and absence of auditory sensory stimulation. All PD+FOG suffered FOG during the task. The presence of auditory rhythmic stimulation (10% above preferred walking cadence) led PD+FOG to significantly reduce FOG. Velocity and cadence were increased, and turn time reduced in all groups. We conclude that auditory stimulation at the frequency proposed may be useful to avoid freezing episodes in PD+FOG.

Circadian Control of Mouse Heart Rate and Blood Pressure by the Suprachiasmatic Nuclei: Behavioral Effects Are More Significant than Direct Outputs:

Diurnal variations in the incidence of events such as heart attack and stroke suggest a role for circadian rhythms in the etiology of cardiovascular disease. The aim of this study was to assess the influence of the suprachiasmatic nucleus (SCN) circadian clock on cardiovascular function. Heart rate (HR), blood pressure (BP) and locomotor activity (LA) were measured in circadian mutant (Vipr2−/−) mice and wild type littermates, using implanted radio-telemetry devices. Sleep and wakefulness were studied in similar mice implanted with electroencephalograph (EEG) electrodes. There was less diurnal variation in the frequency and duration of bouts of rest/activity and sleep/wake in Vipr2−/− mice than in wild type (WT) and short “ultradian” episodes of arousal were more prominent, especially in constant conditions (DD). Activity was an important determinant of circadian variation in BP and HR in animals of both genotypes; altered timing of episodes of activity and rest (as well as sleep and wakefulness) across the day accounted for most of the difference between Vipr2−/− mice and WT. However, there was also a modest circadian rhythm of resting HR and BP that was independent of LA. If appropriate methods of analysis are used that take into account sleep and locomotor activity level, mice are a good model for understanding the contribution of circadian timing to cardiovascular function. Future studies of the influence of sleep and wakefulness on cardiovascular physiology may help to explain accumulating evidence linking disrupted sleep with cardiovascular disease in man.

Bias Due to Changes in Specified Outcomes during the Systematic Review Process:

Adding, omitting or changing outcomes after a systematic review protocol is published can result in bias because it increases the potential for unacknowledged or post hoc revisions of the planned analyses. The main objective of this study was to look for discrepancies between primary outcomes listed in protocols and in the subsequent completed reviews published on the Cochrane Library. A secondary objective was to quantify the risk of bias in a set of meta-analyses where discrepancies between outcome specifications in protocols and reviews were found. New reviews from three consecutive issues of the Cochrane Library were assessed. For each review, the primary outcome(s) listed in the review protocol and the review itself were identified and review authors were contacted to provide reasons for any discrepancies. Over a fifth (64/288, 22%) of protocol/review pairings were found to contain a discrepancy in at least one outcome measure, of which 48 (75%) were attributable to changes in the primary outcome measure. Where lead authors could recall a reason for the discrepancy in the primary outcome, there was found to be potential bias in nearly a third (8/28, 29%) of these reviews, with changes being made after knowledge of the results from individual trials. Only 4(6%) of the 64 reviews with an outcome discrepancy described the reason for the change in the review, with no acknowledgment of the change in any of the eight reviews containing potentially biased discrepancies. Outcomes that were promoted in the review were more likely to be significant than if there was no discrepancy (relative risk 1.66 95% CI (1.10, 2.49), p = 0.02). In a review, making changes after seeing the results for included studies can lead to biased and misleading interpretation if the importance of the outcome (primary or secondary) is changed on the basis of those results. Our assessment showed that reasons for discrepancies with the protocol are not reported in the review, demonstrating an under-recognition of the problem. Complete transparency in the reporting of changes in outcome specification is vital; systematic reviewers should ensure that any legitimate changes to outcome specification are reported with reason in the review.

Clock Quotes

You can’t put a Band-Aid on every boo-boo you’ve made; some just need time to heal…
– Christina Montano

News from PLoS ONE

Over the past week, if you are not a regular visitor to the everyONE blog you may have missed those, we have posted an Update to PLoS Article-Level Metrics Data, the regular Weekly PLoS ONE News and Blog Round-Up and the ‘featured image’ post – Worth a Thousand Words. Check them out.

Crowdsourcing Honesty and Trust

Three thought-provoking reads (even more thought-provoking taken together than each in isolation):
Crowdsourcing Honesty?:

In short, we are far more likely to be honest when reminded of morality, especially when temptation strikes. Ariely thus concludes that the act of taking an oath can make all the difference.

Craig Newmark on the Web’s Next Big Problem:

And what is that? The question of who to trust online, according to Newmark. To solve it, he believes that what the web needs is a “distributed trust network” that allows us to manage our online relationships and reputations. I just happened to have a Flip video camera with me, so I convinced him to let me capture a few minutes of him discussing this concept; I’ve embedded the clip below.

How to Spark a Snowcrash, & What the Web Really Does:

All of us have a trust network already “in real life.” It’s your family and your close friends and colleagues, all those strong ties, and also your extended family, community, and coworkers, your weak ties. These people are crucial, they are your companions day to day. But what about people beyond your real life connections? Is there a way to extend our connections and build trust with strangers who have a diversity of backgrounds, skills, strengths, resources, and knowledge? People who could help us if we needed help? Could we establish a global trust network?
What I discovered through Twitter was that there are people out there who know what community means. Who really, truly know. These people have already internalized what a society could look like based on a cooperative model, and it seems that this is what’s really going on on the web. Beyond all the superficial stuff out there, all the mindless entertainment and porn, at the core (or maybe at the periphery) is a community of….thousands?….millions?….of people who have jobs and careers and passions that they carry out “in the real world,” but have already embraced the vision of a much different way of life that is based in trust.

Clock Quotes

“He has Van Gogh’s ear for music.”
– Billy Wilder

Four things everyone needs to know about sharks (video)


A shark conservation documentary and lesson plan, made by David Shiffman of Southern Fried Science.

ScienceOnline2010: Talks Between Generations (video) – Part 6

Sunday, January 17 at 9-10:05am
E. Science online talks between generationsBeatrice Lugger and Christian Rapp:
Description: In huge meetings around the world several organizations try to initiate a dialogue between top scientists and young researchers -the Lindau Meetings of Nobel Laureates are one of them providing numerous opportunities for an exchange of ideas and thoughts between young researchers and Nobel Laureates. The idea is to support this dialogue with a special platform in the web, where current science topics can be discussed and the talks and thoughts can be followed by a broader public. We’d like to discuss how one can initiate a continued communication process even between two meetings. Which internet/social web tools might be useful to bridge the communication habits of a younger generation with that of an older generation?
The question is if one can organize such a dialogue with a special platform in the web, where current science topics can be discussed and the talks and thoughts can be followed by a broader public.
To get some impressions of the Lindau Nobel Laureates meeting itself please visit the website, click through the archives, read in the annual reports and take a look at the actual list of Nobel Laureates who are expected to join the next meeting (the participation list of young researchers will be online by the end of April 2010).
The aim is to promote the scientific communication between generations. Five short films presented by Nature Video, show some kinds of such a dialogue. Join Laureates and young researchers as they discuss the future of medicine, consider the ethics of nanotechnologies, plan new collaborations, and seek ways to avoid dangerous climate change.
Surely there also exists a blog during the meeting and we are acitve on Facebook and Twitter. Till now the traffic on these plattforms abruptly drops down after the meetings and grows up some weeks before the next one. We’d like to find new ways to encourage a continuous dialogue.

Clock Quotes

Sometimes we are afraid to question because we confuse it with doubt, at times when doubt cannot be indulged. Questioning is not the same thing as doubting. …Living the questions requires a willingness to live with paradox, to endure confusion in our rational minds that only the intuitive mind can entertain: intuition accepts the paradox instead of changing it.
– Christina Baldwin

ScienceOnline2010: Talks Between Generations (video) – Part 5

Sunday, January 17 at 9-10:05am
E. Science online talks between generationsBeatrice Lugger and Christian Rapp:
Description: In huge meetings around the world several organizations try to initiate a dialogue between top scientists and young researchers -the Lindau Meetings of Nobel Laureates are one of them providing numerous opportunities for an exchange of ideas and thoughts between young researchers and Nobel Laureates. The idea is to support this dialogue with a special platform in the web, where current science topics can be discussed and the talks and thoughts can be followed by a broader public. We’d like to discuss how one can initiate a continued communication process even between two meetings. Which internet/social web tools might be useful to bridge the communication habits of a younger generation with that of an older generation?
The question is if one can organize such a dialogue with a special platform in the web, where current science topics can be discussed and the talks and thoughts can be followed by a broader public.
To get some impressions of the Lindau Nobel Laureates meeting itself please visit the website, click through the archives, read in the annual reports and take a look at the actual list of Nobel Laureates who are expected to join the next meeting (the participation list of young researchers will be online by the end of April 2010).
The aim is to promote the scientific communication between generations. Five short films presented by Nature Video, show some kinds of such a dialogue. Join Laureates and young researchers as they discuss the future of medicine, consider the ethics of nanotechnologies, plan new collaborations, and seek ways to avoid dangerous climate change.
Surely there also exists a blog during the meeting and we are acitve on Facebook and Twitter. Till now the traffic on these plattforms abruptly drops down after the meetings and grows up some weeks before the next one. We’d like to find new ways to encourage a continuous dialogue.

Today’s carnivals

Change of Shift Vol. 4- Num. 19 is up at Nursing Student Chronicles
Friday Ark #287 is up on Modulator

New and Exciting in PLoS ONE

Again, looking at papers I personally find interesting….or bloggable. There are 18 new articles today and there were additional 16 articles yesterday in PLoS ONE. As always, you should rate the articles, post notes and comments and send trackbacks when you blog about the papers. You can now also easily place articles on various social services (CiteULike, Mendeley, Connotea, Stumbleupon, Facebook and Digg) with just one click. Here are my own picks for the week – you go and look for your own favourites:
The Spread of Sleep Loss Influences Drug Use in Adolescent Social Networks:

Troubled sleep is a commonly cited consequence of adolescent drug use, but it has rarely been studied as a cause. Nor have there been any studies of the extent to which sleep behavior can spread in social networks from person to person to person. Here we map the social networks of 8,349 adolescents in order to study how sleep behavior spreads, how drug use behavior spreads, and how a friend’s sleep behavior influences one’s own drug use. We find clusters of poor sleep behavior and drug use that extend up to four degrees of separation (to one’s friends’ friends’ friends’ friends) in the social network. Prospective regression models show that being central in the network negatively influences future sleep outcomes, but not vice versa. Moreover, if a friend sleeps ≤7 hours, it increases the likelihood a person sleeps ≤7 hours by 11%. If a friend uses marijuana, it increases the likelihood of marijuana use by 110%. Finally, the likelihood that an individual uses drugs increases by 19% when a friend sleeps ≤7 hours, and a mediation analysis shows that 20% of this effect results from the spread of sleep behavior from one person to another. This is the first study to suggest that the spread of one behavior in social networks influences the spread of another. The results indicate that interventions should focus on healthy sleep to prevent drug use and targeting specific individuals may improve outcomes across the entire social network.

The Young, the Weak and the Sick: Evidence of Natural Selection by Predation:

It is assumed that predators mainly prey on substandard individuals, but even though some studies partially support this idea, evidence with large sample sizes, exhaustive analysis of prey and robust analysis is lacking. We gathered data from a culling program of yellow-legged gulls killed by two methods: by the use of raptors or by shooting at random. We compared both data sets to assess whether birds of prey killed randomly or by relying on specific individual features of the prey. We carried out a meticulous post-mortem examination of individuals, and analysing multiple prey characteristics simultaneously we show that raptors did not hunt randomly, but rather preferentially predate on juveniles, sick gulls, and individuals with poor muscle condition. Strikingly, gulls with an unusually good muscle condition were also predated more than expected, supporting the mass-dependent predation risk theory. This article provides a reliable example of how natural selection may operate in the wild and proves that predators mainly prey on substandard individuals.

Estimating the Potential for Adaptation of Corals to Climate Warming:

The persistence of tropical coral reefs is threatened by rapidly increasing climate warming, causing a functional breakdown of the obligate symbiosis between corals and their algal photosymbionts (Symbiodinium) through a process known as coral bleaching. Yet the potential of the coral-algal symbiosis to genetically adapt in an evolutionary sense to warming oceans is unknown. Using a quantitative genetics approach, we estimated the proportion of the variance in thermal tolerance traits that has a genetic basis (i.e. heritability) as a proxy for their adaptive potential in the widespread Indo-Pacific reef-building coral Acropora millepora. We chose two physiologically different populations that associate respectively with one thermo-tolerant (Symbiodinium clade D) and one less tolerant symbiont type (Symbiodinium C2). In both symbiont types, pulse amplitude modulated (PAM) fluorometry and high performance liquid chromatography (HPLC) analysis revealed significant heritabilities for traits related to both photosynthesis and photoprotective pigment profile. However, quantitative real-time polymerase chain reaction (qRT-PCR) assays showed a lack of heritability in both coral host populations for their own expression of fundamental stress genes. Coral colony growth, contributed to by both symbiotic partners, displayed heritability. High heritabilities for functional key traits of algal symbionts, along with their short clonal generation time and high population sizes allow for their rapid thermal adaptation. However, the low overall heritability of coral host traits, along with the corals’ long generation time, raise concern about the timely adaptation of the coral-algal symbiosis in the face of continued rapid climate warming.

Putting Culture Under the ‘Spotlight’ Reveals Universal Information Use for Face Recognition:

Eye movement strategies employed by humans to identify conspecifics are not universal. Westerners predominantly fixate the eyes during face recognition, whereas Easterners more the nose region, yet recognition accuracy is comparable. However, natural fixations do not unequivocally represent information extraction. So the question of whether humans universally use identical facial information to recognize faces remains unresolved. We monitored eye movements during face recognition of Western Caucasian (WC) and East Asian (EA) observers with a novel technique in face recognition that parametrically restricts information outside central vision. We used ‘Spotlights’ with Gaussian apertures of 2°, 5° or 8° dynamically centered on observers’ fixations. Strikingly, in constrained Spotlight conditions (2° and 5°) observers of both cultures actively fixated the same facial information: the eyes and mouth. When information from both eyes and mouth was simultaneously available when fixating the nose (8°), as expected EA observers shifted their fixations towards this region. Social experience and cultural factors shape the strategies used to extract information from faces, but these results suggest that external forces do not modulate information use. Human beings rely on identical facial information to recognize conspecifics, a universal law that might be dictated by the evolutionary constraints of nature and not nurture.

Statistical Analysis of the Indus Script Using n-Grams:

The Indus script is one of the major undeciphered scripts of the ancient world. The small size of the corpus, the absence of bilingual texts, and the lack of definite knowledge of the underlying language has frustrated efforts at decipherment since the discovery of the remains of the Indus civilization. Building on previous statistical approaches, we apply the tools of statistical language processing, specifically n-gram Markov chains, to analyze the syntax of the Indus script. We find that unigrams follow a Zipf-Mandelbrot distribution. Text beginner and ender distributions are unequal, providing internal evidence for syntax. We see clear evidence of strong bigram correlations and extract significant pairs and triplets using a log-likelihood measure of association. Highly frequent pairs and triplets are not always highly significant. The model performance is evaluated using information-theoretic measures and cross-validation. The model can restore doubtfully read texts with an accuracy of about 75%. We find that a quadrigram Markov chain saturates information theoretic measures against a held-out corpus. Our work forms the basis for the development of a stochastic grammar which may be used to explore the syntax of the Indus script in greater detail.

Calculation of Disease Dynamics in a Population of Households:

Early mathematical representations of infectious disease dynamics assumed a single, large, homogeneously mixing population. Over the past decade there has been growing interest in models consisting of multiple smaller subpopulations (households, workplaces, schools, communities), with the natural assumption of strong homogeneous mixing within each subpopulation, and weaker transmission between subpopulations. Here we consider a model of SIRS (susceptible-infectious-recovered-suscep​tible) infection dynamics in a very large (assumed infinite) population of households, with the simplifying assumption that each household is of the same size (although all methods may be extended to a population with a heterogeneous distribution of household sizes). For this households model we present efficient methods for studying several quantities of epidemiological interest: (i) the threshold for invasion; (ii) the early growth rate; (iii) the household offspring distribution; (iv) the endemic prevalence of infection; and (v) the transient dynamics of the process. We utilize these methods to explore a wide region of parameter space appropriate for human infectious diseases. We then extend these results to consider the effects of more realistic gamma-distributed infectious periods. We discuss how all these results differ from standard homogeneous-mixing models and assess the implications for the invasion, transmission and persistence of infection. The computational efficiency of the methodology presented here will hopefully aid in the parameterisation of structured models and in the evaluation of appropriate responses for future disease outbreaks.

High Levels of Miticides and Agrochemicals in North American Apiaries: Implications for Honey Bee Health:

Recent declines in honey bees for crop pollination threaten fruit, nut, vegetable and seed production in the United States. A broad survey of pesticide residues was conducted on samples from migratory and other beekeepers across 23 states, one Canadian province and several agricultural cropping systems during the 2007-08 growing seasons. We have used LC/MS-MS and GC/MS to analyze bees and hive matrices for pesticide residues utilizing a modified QuEChERS method. We have found 121 different pesticides and metabolites within 887 wax, pollen, bee and associated hive samples. Almost 60% of the 259 wax and 350 pollen samples contained at least one systemic pesticide, and over 47% had both in-hive acaricides fluvalinate and coumaphos, and chlorothalonil, a widely-used fungicide. In bee pollen were found chlorothalonil at levels up to 99 ppm and the insecticides aldicarb, carbaryl, chlorpyrifos and imidacloprid, fungicides boscalid, captan and myclobutanil, and herbicide pendimethalin at 1 ppm levels. Almost all comb and foundation wax samples (98%) were contaminated with up to 204 and 94 ppm, respectively, of fluvalinate and coumaphos, and lower amounts of amitraz degradates and chlorothalonil, with an average of 6 pesticide detections per sample and a high of 39. There were fewer pesticides found in adults and brood except for those linked with bee kills by permethrin (20 ppm) and fipronil (3.1 ppm). The 98 pesticides and metabolites detected in mixtures up to 214 ppm in bee pollen alone represents a remarkably high level for toxicants in the brood and adult food of this primary pollinator. This represents over half of the maximum individual pesticide incidences ever reported for apiaries. While exposure to many of these neurotoxicants elicits acute and sublethal reductions in honey bee fitness, the effects of these materials in combinations and their direct association with CCD or declining bee health remains to be determined.

Clock Quotes

“He uses statistics as a drunken man uses lamp-posts for support rather than illumination.”
– Andrew Lang (1844-1912)

Ants Vs Crabs (video)

Army ants devour a crab:

I would not like to be that crab!
[via Michael Bok]

Today’s must-reads on science communication/journalism

Journalism has always been communal
Top Google queries about scientists: should we be surprised?
Getting more out of scientific content
Telling tales…
The Science Reader: A Crowd-Sourced Profile
Journalism and the public understanding of how science works. A suggested remedy.
So what do the journalists and scientists think?
Evaluating science journalism – with a Matrix!
Ed Yong, Colin Schultz, & More: A bloggitty twitterview conversation on sci-journalism, awesomeness, dirt digging, and wonkiness.
Understanding push-pull market forces and promoting science to under-served audiences
Push vs. Pull strategies in science communication
More on ‘Science blogs and public engagement with science’
Best science writing from the blogosphere!
New blog on science journalism and communication
Engaging the public on science? Surely you’re joking!
Now put all of those ideas together and draw a single conclusion?

New blog on science journalism and communication

First, I would like to welcome Gozde Zorlu to the blogosphere – check out her blog and say Hello. Gozde is a science journalism student with Connie St.Louis (the same class as Christine Ottery who many of you met at ScienceOnline2010).
Gozde is interested in many aspects of science communication and journalism and more:

Here, I’ll be catapulting into the big world wide web my exploration of the social, cultural and political implications of research in science, medicine and the environment. Also, I’ll be blogging about issues to do with science in the media, science education and policy.

In her first post – Journalism and the public understanding of how science works. A suggested remedy., which nominally is a response to this post of mine, but really addresses more deeply the Nature article by Toby Murcott that calls for opening peer reviewers’ comments to journalists, Gozde begins a series of serious, thoughtful essays on the topic. Go and read it, post comments, respond.
You can also follow her on Twitter.
Update: Gozde has now posted her second part of the three-part series: So what do the journalists and scientists think?
Update: I have updated all the links above to reflect the recent migration of the blog to a new address.

ScienceOnline2010: Talks Between Generations (video) – Part 4

Sunday, January 17 at 9-10:05am
E. Science online talks between generationsBeatrice Lugger and Christian Rapp:
Description: In huge meetings around the world several organizations try to initiate a dialogue between top scientists and young researchers -the Lindau Meetings of Nobel Laureates are one of them providing numerous opportunities for an exchange of ideas and thoughts between young researchers and Nobel Laureates. The idea is to support this dialogue with a special platform in the web, where current science topics can be discussed and the talks and thoughts can be followed by a broader public. We’d like to discuss how one can initiate a continued communication process even between two meetings. Which internet/social web tools might be useful to bridge the communication habits of a younger generation with that of an older generation?
The question is if one can organize such a dialogue with a special platform in the web, where current science topics can be discussed and the talks and thoughts can be followed by a broader public.
To get some impressions of the Lindau Nobel Laureates meeting itself please visit the website, click through the archives, read in the annual reports and take a look at the actual list of Nobel Laureates who are expected to join the next meeting (the participation list of young researchers will be online by the end of April 2010).
The aim is to promote the scientific communication between generations. Five short films presented by Nature Video, show some kinds of such a dialogue. Join Laureates and young researchers as they discuss the future of medicine, consider the ethics of nanotechnologies, plan new collaborations, and seek ways to avoid dangerous climate change.
Surely there also exists a blog during the meeting and we are acitve on Facebook and Twitter. Till now the traffic on these plattforms abruptly drops down after the meetings and grows up some weeks before the next one. We’d like to find new ways to encourage a continuous dialogue.

Today’s carnivals

Scientia Pro Publica #23 is up on Pleiotropy
I and the Bird #121 is up on Birder’s Lounge
Four Stone Hearth #88 is up on Ad Hominin
Friday Ark #286 is up on Modulator

Clock Quotes

Pleasure for one hour, a bottle of wine. Pleasure for one year a marriage; but pleasure for a lifetime, a garden.
– Chinese proverb

Push vs. Pull strategies in science communication

Danielle Lee, who just defended her PhD last week (her defense was livestreamed and livetweeted and liveblogged – Congratulations!!!!!!!!!) wrote a very thought-provoking post this morning – Understanding push-pull market forces and promoting science to under-served audiences. Go read it now.
If general public will not actively seek science content (‘pull’) than perhaps we can have the content come to them wherever they are (‘push’). But people are scattered over gazillions of media places! How do we get to them everywhere? One answer is to try to get many people to contribute science-y stories everywhere (or, as I said before, we don’t need one Carl Sagan, we need hundreds…. or thousands of them, each in a different media spot).
But the other important factor, and this is something that Danielle points out and I did not think of clearly before, is that the general population is not homogenous. There are groups that are not scattered all over the fragmented media but flock to specific media outlets that cater to them – media outlets they tend to own or run or work at or write for or have influence on.
Danielle goes into detail about the media consumption of the African American community, but her thoughts apply to other groups as well, e.g., Latinos, or gays, etc. This may also apply to various blogospheres, e.g., mommybloggers, atheist bloggers, feminist bloggers – all groups with strong group identity, congregating at a relatively limited number of media outlets on a regular basis.
One thing that Danielle noted is that media outlets that target African Americans prefer if the science stories are “Africo-Americanized”, i.e., that they specifically hook the audience with something that is directly relevant to that community (and supposedly no other community). Why? Cool science stories are cool for everyone. I suspect that this was more editor-think than the actual response of the audience to Danielle’s science articles that were cool without being ‘Africo-Americanized’.
And some of the communities are more inclined to be interested in science than others, especially those communities that see themselves as ‘reality-based’, thus inherently science-friendly. Thus progressive blogs like DailyKos have regular science coverage both on the main page and in the diaries – cool science stories, as well as science/political controversial topics. Atheist blogs are sometimes indistinguishable from science blogs. Feminist bloggers, like Lindsay Beyerstein, Jesse and Amanda at Pandagon and some of the community bloggers at Shakesville regularly touch on science topics (especially those with either public health concerns, or environmental concerns, or with political controversies associated with them).
But how do we get science stories, purely cool or group-targeted, in front of other audiences, e.g., those based on race/ethnicity, or gender/orientation? Are whites much more scattered across the media than minorities or do they also congregate around their various interests? Where do they congregate? How do we ‘push’ science there where they are? Not just online, but also in big corporate media, especially television?

ScienceOnline2010 – interview with Mary Jane Gore

Continuing with the tradition from last two years, I will occasionally post interviews with some of the participants of the ScienceOnline2010 conference that was held in the Research Triangle Park, NC back in January. See all the interviews in this series here. You can check out previous years’ interviews as well: 2008 and 2009.
Today, I asked Mary Gore from The Duke Medicine Office of News and Communications to answer a few questions.
Welcome to A Blog Around The Clock. Would you, please, tell my readers a little bit more about yourself? Where are you coming from (both geographically and philosophically)? What is your (scientific) background?
I’m a science writer at Duke University Medical Center, which is a great vantage point over many fields of learning. I was a science major, biology at University of Virginia, who always wanted a career as a writer. So going to journalism grad school at the University of Missouri provided the professional direction I needed. Between colleges, I worked three years at National Geographic writing for their image collection and working for their children’s magazine, then called World. Since the journalism degree, I’ve had editorial jobs, and I also freelanced 11 years, before moving into academia.
Oooh! I loved ‘NG World’ when I was a kid – a family friend in the USA bought me a subscription and I read every issue many times through.
Tell us a little more about your career trajectory so far: interesting projects past and present?

I’m so fortunate to have landed at a Top 10 medical school where the scientists within the various schools are so collaborative and supportive of each other’s work, by and large. That makes for interesting work of all sorts. What become the biggest stories, for me as a science writer, aren’t always the most predictable topics: diet and sex, for instance. In the two years I have been at Duke, the biggest story (and one I still get emails about) was Bryan Cullen’s RNA findings involving the virus that causes cold sores. The popularity of that story – a very basic science finding – was because of the sheer numbers: nearly 90 percent of people get the darn things, and any hope for a cure – even in the future – is news.
Mary Gore pic.jpg
I have worked as a medical writer most of my professional career, but as an 11-year freelancer I took on a lot of assignments. I even had scripts produced for a TV show (Divorce Court). Writing about divorce was a fictional activity back then – and now you can’t make this stuff up. It’s what we have to compete with.
What is taking up the most of your time and passion these days? What are your goals?
My time is mainly spent in publicizing basic or translational biomedical science. My passion is to do my part to make the world understand that science is more important than celebrity. I am not so starry-eyed as to think that science will catch celebrity in the headline-making arena – but I do hope to see more medical and biomedical science in more places where people get their news. I sincerely believe that informing the public as much as I – and as we – can about early and late-stage research is going to help save the planet. I have two kids, so it’s important to me to discuss the issues. Not that he went out of his way to be my Facebook friend, but there I can see he has a bit of the awareness I was hoping for.
What aspect of science communication and/or particular use of the Web in science interests you the most?
I am always trying to learn better ways to reach the broadest audience with one story. It’s interesting to try different tactics with different stories. One week it may be science websites and blogs that pick up the story – in fact, that happens most weeks. In other conditions, it may be the mainstream media, but there nearly always has to be either a translational component or a dangerous disease/condition for which there may be a promising, though early, finding. Even great science stories disappear when there are predominant stories, like the Haiti Earthquake, health care reform near-passage, the presidential election. The growing number of outlets online is pleasing. But my question is: who can synthesize all of these stories and make sense of it? Which sites are really the best go-to sites? For example, where are we, really, in the fight against cancer? There are thousands of bits of information. It feels hard to keep up, to know the best places to go for each subject.
How does (if it does) blogging figure in your work? How about social networks, e.g., Twitter, FriendFeed and Facebook? Do you find all this online activity to be a net positive (or even a necessity) in what you do?
So far, I am not a blogger at all. I do read them – yours comes to my inbox, but it is one of the few I subscribe to, because of time constraints I feel. Now that so many MSM science writers are gone from their posts, I think blogs will be further enriched. Maybe I’ll subscribe to more. I think we all have inbox fatigue. I have helped Duke scientists write about their findings for Huffington Post, and that is something I am proud of, given the potential readership by influential readers of those blogs who may be looking for sound information. I think blogging science news is a net positive. People need to learn about scientific findings – reported with accuracy – in any way they can.
When and how did you first discover science blogs? What are some of your favourites? Have you discovered any cool science blogs by the participants at the Conference?
I wasn’t much of a blog reader until I came to Duke two years ago, and, in a nicely old-fashioned way, was introduced to you at Anton Zuiker’s home. That is really old-school – getting a personal introduction to the blogger – and in fact, that is what happens at Science Online ’10 – isn’t it? We all can meet in person and share. I like Ed Yong’s approach, and Ars Technica, and I like Neurophilosophy. I have been reading Carl Zimmer, and not just for the animal sex posts — I read him before that. I like Rebecca Skloot, too, and XX Factor on Slate. Oh, and Sandra Tsing Loh, the Loh Down on Science (a radio show, not a blog).
What was the best aspect of ScienceOnline2010 for you? Any suggestions for next year? Is there anything that happened at this Conference – a session, something someone said or did or wrote – that will change the way you think about science communication, or something that you will take with you to your job, blog-reading and blog-writing?
It’s a very democratic meeting; the accessibility to all others, including the gracious speakers, is good.
The Journalism session was the standout for me – it hurt to realize that the information we give as PIOs is considered so specious to some other writers. Thank you for your recent defense of PIOs as a source of science writing. We each have a communication job to do. Mine is to publicize the works, large and small of the scientists at Duke in biomedical fields. But as a trained journalist and one who freelanced as a writer for 11 years before going into full-time work in academia, I do strive to provide accurate science stories, double-check statistics and other data, and include thoughtful quotes from the scientists. Maybe part of my personal mission is to get young people interested in science, too, with bright, encouraging, affirming quotes from those who are practicing.
It was so nice to see you again and thank you for the interview. I hope you come again next January.