Category Archives: Open Science

Importance of cell phones (not internet) in health-care in the developing world

Can You Heal Me Now?

While many Americans view cell phones as indispensable to their social and professional lives, more and more Africans are finding cell phones to be indispensable to good health. In sub-Saharan villages, for example, mobile phones are playing a key role in health care delivery, says Dr. Fay Cobb Payton, an associate professor of information systems and technology in the NC State College of Management.
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“The pervasive use of mobile technology surprised me,” she says, noting cellular towers have arrived in many parts of Africa before land lines. “The Internet is an expensive proposition for many areas, but even in the smallest villages, people have mobile phones and use them widely.”
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Nurses used to travel to rural villages and bring back notes about each patient, which had to be transcribed before a physician was consulted. Text messages, cell phone pictures, and cell phone video now allow nurses in the field to transmit patient conditions and histories directly to physicians in the clinic for faster consultations.
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“It’s not enough to drop technology into an area,” she says. “We need to educate patients and physicians on the cost and care benefits and provide ongoing training so they become comfortable with using the technology to improve public health.”

Open Access Day is approaching fast!

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Open Access Day is on October 14th. This day is organized by SPARC, Students for FreeCulture and PLoS.
Why?

Open Access is a growing international movement that uses the Internet to throw open the locked doors that once hid knowledge. It encourages the unrestricted sharing of research results with everyone, everywhere, for the advancement and enjoyment of science and society.

You should participate and register. Already, there are 100 organizations taking part, and the registration closes tomorrow so you have to act fast!
You can help by spreading the word. On October 14th, there will be a lot of stuff to do and some cool videos to watch (and embed into your sites).
And if you are a blogger, get ready for the contest – the details of the blogging competition will be posted next Friday (October 10th) on the Open Access Day blog, on the PLoS blog and right here, on my blog, so come back and check it out next week.

Zerhouni to step down

As you may have already heard, Alias Zerhouni will step down from his position of the NIH director in October, not waiting for the inauguration of a new Administration. He has been a strong and effective proponent of Open Access and I hope his successor will be as well. The blogospheric responses are all over the spectrum, from very positive to very negative, depending on what aspects of his tenure are the focus. Here are some examples:
Heather Morrison:

Dr. Zerhouni has led the NIH through the long process of the NIH Public Access mandate, first the voluntary policy, then the mandatory one, most recently speaking up forcefully for the NIH and against the absurd Conyers bill. The NIH is the world’s largest medical research funder, and from my viewpoint, this is one of the OA initiatives that has been the subject of the most intense lobbying efforts. Thank you, Dr. Zerhouni. Public access is a great gift to the world; it is appreciated, and you will be missed.

Charles W. Bailey, Jr.:

The National Institutes of Health has announced the resignation of its Director, Elias A. Zerhouni, M.D., from that post effective at the end of October 2008. Zerhouni has been a strong open access advocate.

Nick Anthis:

Eliot Zerhouni has overseen the NIH at difficult time, when its budget has been stagnant, leading to a precipitous decline in grant success rates. Two decent accomplishments, however, that occurred during his tenure were ethics reform and the NIH’s new policy on open access to publications funded by its research dollars. The legacy of what’s more commonly touted (at least by Zerhouni) as his major achievement–the NIH Roadmap–remains more dubious, as it is often blamed for siphoning funding away from more basic and higher-risk research.

Revere (also here):

Zerhouni presided over tumultuous years at NIH. The doubling of the NIH budget in the five years prior to 2003 created a pig in a python effect when the budget flatlined and all the new post docs, graduate students, laboratories and research projects stimulated by the doubling were left high and dry. Now the budget is at about what it was in real dollars before the doubling but there are many more mouths to feed and lab benches to maintain. Basic health research is facing its own financial meltdown as existing grants aren’t being renewed and the hands that do the work — the post docs and graduate students — are leaving the field and the research programs they were a part of are withering. This is creating a crisis in leadership in academic science in the US, as the post docs leave for other work and the mid level academics coming up for tenure can’t get their grants renewed and have to leave their institutions to look for other positions and start over or leave research altogether.

DrugMonkey:

Unsurprising since this is a political appointment and all. You did know that, right? More importantly and probably more concerning will be the dance of the IC Directors.
The directors of the NIH Institutes and Centers are slightly less political in nature but there are still allegiances. And the highly activist Directors can have immediate impact on what research grants get funded, etc. So the scientists who are funded by an IC which has a Director resign may want to pay some attention. A long interval of an Acting Director can, conversely, maintain status quo on the funding side but may seriously side-line Congressional advocacy for the IC’s mission.

writedit:

Given that the Great Zerhouni, like all political appointees, would have been submitting his resignation come January 2009, this is a bit odd he would bail a few months shy, especially since Kessler as FDA director set the precedent of straddling administrations (& parties in power; h/t BB). If the GZ had wanted to stay, it wasn’t out of the question. And with the CTSA Consortium just about to fill up and the T-R01s pouring in next January, I’m a bit surprised. Plus, if he truly wanted as minimal disruption as possible, he would have waited for the next appointed director to be approved by the Senate before stepping down. Someone will have the thankless job of serving as interim director for 6-8 months.

‘Advancing Science Through Conversations’ article – summary of the blogospheric responses

The PLoS Biology article about science blogs and their (potential) relationship to the academic institutions has, as expected, received quite a lot of coverage in the blogosphere. Nick collects the responses and responds to the responses – join in the conversation in the comments there. Update: So does Tara.
Update: Jessica’s post is what I would have written. Now I don’t need to – go read hers.

Debate! Open Access for the Public

Go to Mimi’s place and state your position:

For a long time, if you wanted to read up on science news or get background information for research, you had to hope that the media got it right, have a subscription to a few journals ( there are thousands though, so you are missing out), or be lucky enough to work at an institute/organization that gives you access to journals online and has a few (hundred) bound copies. Before legislation was passed to make NIH funded research available to the public after a year, no one really knew what was going on in the world of research and development.
This sounds great for some, but for scientists and certain publishing houses, this is a topic of much contention. In fact, OA was in recent legislation again! So I guess the question up for discussion this week is…do you think research should be made available to the public for free or is this going to destroy tiny publishing houses and let the big ones float? How will this affect genetics testing and privacy of subjects? How do you feel about open access?

Science beyond individual understanding?

Michael Nielsen wrote another long thought-provoking essay (for his book, I guess):

…………Two clarifications are in order. First, when I say that these are examples of scientific facts beyond individual understanding, I’m not saying a single person can’t understand the meaning of the facts. Understanding what the Higgs particle is requires several years hard work, but there are many people in the world who’ve done this work and who have a solid grasp of what the Higgs is. I’m talking about a deeper type of understanding, the understanding that comes from understanding the justification of the facts.
Second, I don’t mean that to understand something you need to have mastered all the rote details. If we require that kind of mastery, then there’s no one person who understands the human genome, for certainly no-one has memorized the entire DNA sequence. But there are people who understand deeply all the techniques used to determine the human genome; all that is missing from their understanding is the rote work identifying all the DNA base pairs. The examples of the LHC and the classification of the finite simple groups go beyond this, for in both cases there are many distinct deep ideas involved, too many to be mastered by any single person. …………..
……………..Such scientific discoveries raise challenging issues. How do we know whether they’re right or wrong? The traditional process of peer review and the criterion of reproducibility work well when experiments are cheap, and one scientist can explain to another what was done. But they don’t work so well as experiments get more expensive, when no one person fully understands how an experiment was done, and when experiments and their analyses involve reams of data or ideas.
Might we one day find ourselves in a situation like in a free market where systematic misunderstandings can infect our collective conclusions? How can we be sure the results of large-scale collaborations or computing projects are reliable? Are there results from this kind of science that are already widely believed, maybe even influencing public policy, but are, in fact, wrong?

Discuss…..

Creating an Open Forum to Advance Global Health and Social Justice

At Harvard, a week ago:
Recap: Wednesday’s Health and Human Rights Discussion

Yesterday afternoon at the Loeb Theater, Harvard hosted a forum celebrating the tenth edition of their journal Health and Human Rights. This edition is the journal’s first to be presented in open-access format, meaning that anyone can read it without paying the exorbitant fees associated with most journal articles. Bostonist was in the front row as Agnes Binagwaho, Gavin Yamey, Philip Alston, and Paul Farmer (profiled as “a man who would cure the world” by Tracy Kidder) discussed the past, present, and future of global health policy.
The most compelling aspect of the discussion dealt with the dilemmas faced by doctors worldwide, and particularly in areas like sub-Saharan Africa, in instituting the best practices for treating AIDS and other serious outbreaks. Most hospitals have extremely tight budgets, forcing them to rely on free (and sometimes factually incorrect) abstracts of published research, rather than the expensive full papers. This can cause trouble: Yamey noted that one South African hospital worsened its AIDS treatment program because of erroneous information contained in the abstract of a journal article. Yamey went on to say, “removing access barriers will… share the learning of the rich with the poor and the poor with the rich.” This sentiment was echoed by Binagwaho, who heads up the effort to combat AIDS in Rwanda, and noted that increased Internet availability combined with open-access publication will enable rapid implementation of new treatment techniques at the community level.

Making the case for the right to health

Dr. Binagwaho reflected on the irony of research done in developing countries that is never available to the study subjects, and she applauded efforts like PLoS and HHR Journal for working to promote access to a wider audience. In addition, she stressed the need for intellectual exchange. She saw these discussions as “necessary to make the best decisions.” Citing the example of GHDonline.org, she told of the value for herself and others in executive positions to bounce ideas off of each other (for example, should children of HIV-positive parents undergo mandatory testing?) and also the value gained by including field workers in the conversation. “People at the community level may not have the theories, but they have the knowledge,” she said. Finally, she outlined that the sum of these efforts, of fighting for access to health, information, and education, is to eliminate poverty.
Dr. Yamey focused on the need to change the way we look at medical publications. He points out that information is so expensive to access that patients, and many doctors and researchers, can simply not afford to survey the literature and make fully informed decisions. “Only a tiny fraction of the intended audience can read a work. This paradigm is wrong — medical research should be a global public good.” The consequences of the current model are hazardous: often, doctors and patients are forced to rely on abstracts, which convey “dangerous half-truths.” Also, because researchers in the global south often have less access to literature than their counterparts in the north, a dynamic of inequality is introduced in their interactions. The world would benefit from a “knowledge commons,” which would better allow research and practice efforts to “build on the shoulders of giants.” Dr. Yamey was instrumental in getting the journal online in an open access format, and he applauded the journal’s new format.

BlogOpen-South East, regional friendly and professional meeting of bloggers

Danica announced:

The third BlogOpen: meeting of all the participants in blogosphere (from authors, readers, IT workers to mainstream media) will happen on October 4-5 in in Bor, Brestovacka banja, Serbia. Main goals of this public meeting are:
1. Discussion about the topics and problems characteristic of this manner of public communication;
2. Realization of virtual communication in real, public space;
3. Calling wider public’s attention to this mode of authors’ presence and to the importance of an information society;
4. Promotion of an information society, electronic communication and the role of Internet as a source of information, educative tool, interpersonal networking and fostering of democracy;
5. Making notice of the most significant and most successful blogging authors and their impact as creators of public opinion and as sources of information.
More about BlogOpen in English and some valuable information – on this page, the list of speakers is here, and the program. I’m inviting all of you who are interested in these topics to join us as this will be great opportunity to participate and discuss different range of current burning issues, as well as to brainstorm and contribute in some solutions not only in local/world wide blogosphere but in social media and alternative education processes. You can register here. If you are not able to come, I’ll twitter from the conference some interesting points and thoughts.

Science, Art, Education, Communication

The September 2007 issue of JCOM – Journal of Science Communication – (issue 3, volume 7) is online.: Next issue will be online on the 18th December 2008. There are several articles in this issue that I find interesting and bloggable.
Contents:

Continue reading

ACTION: let’s kill this anti-OA bill before it’s even born!

You probably remember the wonderful new NIH law that passed last year:

On Dec 26th, 2007, President Bush signed the Bill that requires all NIH-funded research to be made available to the public.

The bill mandates all NIH-funded research to be made freely available to public within 12 months of publication.
You probably also remember that the big publishers opposed the law, using some very unsavoury tactics. Well, guess what? They are at it again. They are trying to sneak through Congress a new bill that is, in essence, the repeal of the NIH open access law. The bill, dubbed in a typical double-speak Orwellian fashion “Fair Copyright in Research Works Act (HR6845)” has now been introduced. It may not get out of committee in this Congress, but probably will after the new Congress is seated.
David Dooling writes:

Since Congress voted to encourage NIH to adopt an open access policy for scholarly publications that resulted from research it funded, the journal publishers have lobbied Congress to reverse it. It seems the efforts of publishing companies are beginning to pay off with the introduction of the bill HR 6845. The bill would shift rights away from the article authors, the researchers, and back to large publishing houses. In an age of internet publishing and voluntary peer review, what possible reason could their be for such a shift? How would increasing restrictions on scientific publications increase openness and access to scientific discovery, the very foundation of scientific advancement? These sort of copyright issues cut across the partisan divide, typically aligning members of Congress from both parties from areas of the country with strong content generation industries (TV, movies, music, print). In other words, members of Congress from California, New York, and Florida (Disney) or committee chairs who get a lot of money from these big media companies typically introduce and support these anti-competitive, anti-scientific pieces of legislation. This bill is no exception, being sponsored by John Conyers (D-MI), Darrell Issa (R-CA), Robert Wexler (D-FL), and Tom Feeney (R-FL).

John Timmer says:

In recent years, scientific publishing has changed profoundly as the Internet simplified access to the scientific journals that once required a trip to a university library. That ease of access has caused many to question why commercial publishers are able to dictate the terms by which publicly funded research is made available to the public that paid for it.
Open access proponents won a big victory when Congress voted to compel the National Institutes of Health to set a policy of hosting copies of the text of all publications produced by research it funds, a policy that has taken effect this year. Now, it appears that the publishing industry may be trying to get Congress to introduce legislation that will reverse its earlier decision under the guise of strengthening copyright protections.

And Revere adds:

I am one of those NIH supported researchers whose papers get locked up for decades behind copyright permission firewalls. I want you to have access to my research. I want the journals I publish in to be required to make it available to you after a reasonable time period (the shorter the better) as the NIH policy now does. It helps me professionally by making my work more widely disseminated. It helps me as a professional by making it possible to get access to scientific research, now inaccessible because of the predatory and outrageous charges of the large scientific publishers, the same people behind the Conyers legislation.

You can read more about the intentions of the bill here.
What can you do? Call your congresscritters and ask them to bury this bill. You have only until September 24th to do so!
There is a sample letter under the fold (along with the contact info for Congress), but it is usually much better if you write one of your own. If so, make it short, make it simple (so an average congressman can understand it), make it positive (better than bashing the slimy opposition) and make it personal (why do you personally support Open Access).
Then, use whatever online and offline tools are at your disposal (blogs, twitter, friendfeed, e-mail, newsgroups, personal contact) and spread the word – urge all your friends and colleages to contact their Representatives and Senators and ask them to Just Say No.

Continue reading

ScienceOnline’09 – Registration is Open!

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First, there was the First NC Science Blogging Conference. Then, there was the Second NC Science Blogging Conference. And yes, we will have the Third one – renamed ScienceOnline’09 to better reflect the scope of the meeting: this time bigger and better than ever.
ScienceOnline’09 will be held Jan. 16-18, 2009 at the Sigma Xi Center in Research Triangle Park, NC.
Please join us for this free three-day event to explore science on the Web. Our goal is to bring together scientists, bloggers, educators, students, journalists, writers, publishers, Web developers and others to discuss, demonstrate and debate online strategies and tools for promoting the public understanding of science.
The conference is organized jointly by BlogTogether, the North Carolina bloggers’ group, and WiSE @ Duke, the Women in Science and Engineering organization at Duke University, with help from Sigma Xi and other sponsors.
The people behind the organization are Anton Zuiker, Abel Pharmboy and myself, with additional generous help by Brian Russell and Paul Jones.
The conference homepage/wiki is now live! Go and explore!
Registration is free and it is now open – go and Register right now!
See who has already registered.
Help us develop the Program.
Perhaps your organization/company would like to be a sponsor? Or you’d like to volunteer?
Just like last two times, we are preparing the publication of the Science Blogging Anthology and, this time, we’ll try to really have it ready and up for sale at the conference itself. This year’s Guest Editor is Jennifer Rohn and you should really start submitting your entries now.
For news and updates about the conference (and anthology), follow the ScienceOnline09 blog or check here, my SO’09 category.
Hope to see many of you in January!

A video is worth a thousand fliers

Vedran tells me that people from the Oncology Institute in Belgrade, who usually give women little brochures that describe breast self-exam in words, are now using – and loving – the two videos (originally from here) he has embedded into his Gynecology aggregator. Another win for Open Access.

Open Access and science blogs in the Anglo-American School in Belgrade

Vedran continues to spread the Openness in Serbia:

Anglo-American School Belgrade, a small private school in Belgrade, started its academic year with an opening ceremony celebrating the joy of learning.
Teachers who gathered on the first day of school learned about the intention of the school management to offer them a number of links to Open Access repositories and Open Access RSS feed aggregators for use in educational practice. Teachers learned about the freedom of knowledge and, with great enthusiasm, started to explore a variety of resources of information in order to enrich lectures and to train the students to seek the information and knowledge on the Internet by using Open Access repositories, scientific blogs, open notebook and other methods of disseminating freedom of information and knowledge.
PLoS and scientific blogs were found very attractive due to possibility to communicate with scientists directly. The parents supported the school’s intentions to offer more resources of information and knowledge and to follow efforts of scientists worldwide to share their experiences, thought and knowledge.”

Towards a Data Sharing Culture

Towards a Data Sharing Culture: Recommendations for Leadership from Academic Health Centers:

Sharing biomedical research and health care data is important but difficult. Recognizing this, many initiatives facilitate, fund, request, or require researchers to share their data [1-5]. These initiatives address the technical aspects of data sharing, but rarely focus on incentives for key stakeholders [6]. Academic health centers (AHCs) have a critical role in enabling, encouraging, and rewarding data sharing. The leaders of medical schools and academic-affiliated hospitals can play a unique role in supporting this transformation of the research enterprise. We propose that AHCs can and should lead the transition towards a culture of biomedical data sharing.
The benefits of data sharing and reuse have been widely reported. We summarize them here, from the perspective of an AHC….

ResearchBlogging.org, v.2.0

The cat is out of the bag! The version2.0 of ResearchBlogging.org is ready to go and you can test it out:

After a week of late nights and hard coding, our development team has released the beta version of the site to our entire userbase! You can visit the new site here:
http://72.32.57.144/index.php/
We are planning on launching the site at the researchblogging.org address over the weekend, but you can get a head start now setting up your account, customizing it the way you like, and trying out all our new features. (note: All passwords have been reset, so you’ll need to use the “forgot password?” link to set your password)
There will be much, much more on our official launch date of September 2, but here is a partial list of new features:
* Multiple language support (and 30 new German-language bloggers!)
* Topic-specific RSS feeds
* Post-by-post tagging with topics and subtopics
* “Recover password” feature
* Email alerts when there is a problem with posts
* Users can flag posts that don’t meet our guidelines
* Customized user home pages with bios and blog descriptions
* Blogger photos/other images displayed with each post
* Multiple bloggers per blog
* Multiple blogs per blogger
* Advanced troubleshooting features
We’re super excited that the system is ready to go, and we look forward to seeing you on the new site!

Well, we took a little look at the PLoS HQ and noticed that out of 87 pages of ‘all results’ there are 8 pages of ‘PLoS’ results – implying that about 10% of all the BPR3 posts are on PLoS papers from all seven journals – and of those, 4 pages are just on PLOS ONE papers – which is about 5%. All I can say is w00t! for Open Access – when bloggers can read, bloggers will write.

Open Access Day!

SPARC, Students for FreeCulture and PLoS are organizing the first ever Open Access Day on October 14, 2008. This is also the 5th birthday of PLoS Biology, the oldest of seven PLoS journals.
For this occasion, the organizers have put together a nice website/blog where you can find all the information. You can watch videos (two so far, but there will be more). You can help spread the word:

You can get prizes. Or you can enter the blog contest:

Coming soon…
Prior to Open Access Day, bloggers will be invited to draft a personal post addressing the following key points:
* Why does Open Access matter to you?
* How did you first become aware of it?
* Why should scientific and medical research be an open-access resource for the world?
* What do you do to support Open Access, and what can others do?
We will ask the community to time these posts for release on Open Access Day so that the whole blogosphere gets the message that Open Access matters! A series of videos is also being prepared to address the same questions.
PLoS and (we hope) another prestigious publishing partner will then choose the winner and announce it on their respective sites. A free goodie bag including an iPod Nano, and other items (T-shirts, etc.) will be the prize for the most compelling post.
Watch this space…

But to win the blog contest, you first have to deal with Dorothea… 😉 Steve Lawson seems to have already conceded defeat to her. You should not!

Post-publication Peer-review in PLoS-ONE, pars premiere

Why is the letter P the most useful for alliterative titles?
But back to the substance. One thing that bugged me for a long time is that I often see on blogs or hear in person a sentiment that “there are no comments on PLoS ONE”. Yet I spend quite some time every week opening and reading all the new comments so I KNOW they are there and that there is quite a bunch of them already. Why the difference in perception? Is it due to the predictable distribution (a few papers get lots of comments, most get one or none, just like blog posts)?
So, when we saw this nice analysis of commenting on BMC journals by Euan Edie, we decided to take a look at our own numbers and see how they compare. We got the data together and sent them to a few people, mostly bloggers, to take a look. As they write their blog posts I will post the links here, especially when they do the nitty-gritty statistical analysis.
But for now, quickly out of the box, two of them have already posted their first impressions they took when they scanned the data.
Deepak Singh writes:

There people post a link and a whole discussion erupts (not always, but often enough). I would throw out this challenge (see the DOI suggestion above). Why should discussion be localized to PLoS One itself. If a paper pubished in PLos One is discussed in 20 other places, it would be considered a success. In other words, we shouldn’t limit our thinking to just on site commenting. Perhaps within the site, we should be focussed on ratings and perhaps tagging and notes.
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So what have we learned from this exercise. Quite frankly, I am not sure. Is the commenting on PLoS One at a level that we hoped it would be? Not quite. Is it as bad as some might like to believe? Not quite. What we have is a very very nascent (no pun intended) effort on the part of the scientific community using web publishing platforms as a communication medium. I’d like to ask those same scientists to think about newsgroups. Most scientists are fairly comfortable participating in newsgroups, and here you essentially have one, with very clearly defined thread titles.

Cameron Neylon says:

In that context, I think getting the numbers to around the 10-20% level for either comments or ratings has to be seen as an immense success. I think it shows how difficult it is to get scientists to change their workflows and adopt new services. I also think there will be a lot to learn about how to improve these tools and get more community involvement. I believe strongly that we need to develop better mechanisms for handling peer review and that it will be a very difficult process getting there. But the results will be seen in more efficient dissemination of information and more effective communication of the details of the scientific process. For this PLoS, the PLoS ONE team, as well as other publishers, including BioMedCentral, Nature Publishing Group, and others, that are working on developing new means of communication and improving the ones we have deserve applause. They may not hit on the right answer first off, but the current process of exploring the options is an important one, and not without its risks for any organisation.

There are also two quick responses on Nascent and Genome-Technology.
What is most interesting is that there are no comments on Nascent and Genome-Technology, only a couple on Deepak’s and Cameron’s posts, yet a very nice long discussion on FriendFeed (very much worth reading, and not just for compliments to me)! What can we learn from that fact alone?
Second, the comment (by ‘comment’ I mean Ratings+Notes+Comments) to article ratio on PLoS ONE has risen from 1.1 a year ago to about 1.5 today. For comparison, my own blog has 1.6. And I get lots of comments – on a few posts, while zero or one on most. And I am prolific with quick/short posts like Quotes, so it is a decent comparison: not every paper is exciting or controversial enough (just like most of my posts are not) to motivate people to say anything.
Also, a blog post usually gets comments immediately. After 24 hours it is deemed stale and people move on to the new stuff. A scientific paper will be expected not to get any for the first few months and to only gradually accumulate them over the years as new information comes in that sheds new light on that paper. And I see this every week – older papers get a nice share of comments every week, while papers published this week do not.
See what I wrote last year about this:

One thing to keep in mind is that a PLoS ONE article is not a blog post – the discussion is not over once the post goes off the front page. There is no such thing as going off the front page! The article is always there and the discussion can go on and on for years, reflecting the changes in understanding of the topic over longer periods of time.
Imagine if half a century ago there was Internet and there were Open Access journals with commenting capability like PLoS ONE. Now imagine if Watson and Crick published their paper on the DNA structure in such a journal. Now imagine logging in today and reading five decades of comments, ratings and annotations accumulated on the paper!!!! What a treasure-trove of information! You hire a new graduate student in molecular biology – or in history of science! – and the first assignment is to read all the commentary to that paper. There it is: all laid out – the complete history of molecular biology all in one spot, all the big names voicing their opinions, changing opinions over time, new papers getting published trackbacking back to the Watson-Crick paper and adding new information, debates flaring up and getting resolved, gossip now lost forever to history due to it being spoken at meetings, behind closed door or in hallways preserved forever for future students, historians and sociologists of science. What a fantastic resource to have!
Now imagine that every paper in history was like that (the first Darwin and Wallace letters to the Royal Society?!). Now realize that this is what you are doing by annotating PLoS ONE papers. It is not the matter so much of here-and-now as it is a contribution to a long-term assessment of the article, providing information to the future readers that you so wished someone left for you when you were reading other people’s papers in grad school and beyond. Which paper is good and which erroneous (and thus not to be, embarrassingly, cited approvingly) will not be a secret lab lore any more transmitted from advisor to student in the privacy of the office or lab, but out there for everyone to know. Every time you check out a paper that is new to you, you also get all the information on what others think about it. Isn’t that helpful, especially for students?

I hope more of you join in the discussion, and I will post links to other posts as they appear over the next week or two.

Victoria Stodden: Open Source Science-Open Research License

From SciFoo 08:

Victoria Stodden discusses her efforts to create a new license for scientific research which covers both publication and data. She discusses the motivations behind the new license and the issues brought up by releasing scientific research and data under and open source license.
Copyright 2008 O’Reilly News. All Rights Reserved. Filmed at Scifoo 2008 at the Googleplex in Mountain View, CA by Tim O’Brien.

How do you know in advance what you will discover so you can say so in your grant proposal?

Jean-Claude Bradley reviews Happy Accidents: Serendipity in Modern Medical Breakthroughs by Morton A. Meyers. Morton says:

An applicant for a research grant is expected to have a clearly defined program for a period of three to five years. Implicit is the assumption that nothing unforeseen will be discovered during that time and, even if something were, it would not cause distraction from the approved line of research. Yet the reality is that many medical discoveries were made by researchers working on the basis of a fallacious hypothesis that led them down an unexpected fortuitous path.

Jean-Claude adds:

We can share our failed experiments. We can share our research plans. We can discuss science freely admitting what we don’t know. We can record our talks at closed meetings and make them public. We can initiate and participate in serious scientific conversations going on in the blogosphere without worrying about everyone’s title and rank.
Basically, we can collaborate in ways that are most conducive to serendipitous discoveries. The free social software, databases and other infrastructure now available make this information exchange easier than ever.

Court win for Fair Use

Judge Rules That Content Owners Must Consider Fair Use Before Sending Takedowns:

A judge’s ruling today is a major victory for free speech and fair use on the Internet, and will help protect everyone who creates content for the Web. In Lenz v. Universal (aka the “dancing baby” case), Judge Jeremy Fogel held that content owners must consider fair use before sending takedown notices under the Digital Millennium Copyright Act (“DMCA”).

Some interesting data about Impact Factors

For those of you interested in the science publishing business, there is an interesting paper out about Impact Factors, where they do the math to try to explain why the IFs are apparentluy always rising from year to year, and to figure out the differences between disciplines. They remain agnostic pretty much about the whole hot controversy about the validity of IF, but their data explain some facts about IF that can be added, IMHO, into the growing lists of reasons why IF should be abandoned:
Althouse, B.M., West, J.D., Bergstrom, C.T., Bergstrom, T. (in press). Differences in impact factor across fields and over time. Journal of the American Society for Information Science and Technology DOI: 10.1002/asi.20936

The bibliometric measure impact factor is a leading indicator of journal influence, and impact factors are routinely used in making decisions ranging from selecting journal subscriptions to allocating research funding to deciding tenure cases. Yet journal impact factors have increased gradually over time, and moreover impact factors vary widely across academic disciplines. Here we quantify inflation over time and differences across fields in impact factor scores and determine the sources of these differences. We find that the average number of citations in reference lists has increased gradually, and this is the predominant factor responsible for the inflation of impact factor scores over time. Field-specific variation in the fraction of citations to literature indexed by Thomson Scientific’s Journal Citation Reports is the single greatest contributor to differences among the impact factors of journals in different fields. The growth rate of the scientific literature as a whole, and cross-field differences in net size and growth rate of individual fields, have had very little influence on impact factor inflation or on cross-field differences in impact factor.

Christina looks at their math and summarizes the paper as well:

Impact factors of journals are a perennial discussion topic – used by libraries (with other measures) for collection development and by researchers to decide where to publish. They’re also mis-used, abused, and misunderstood. But this article isn’t about all that. This article looks at whether the impact factors are going up, what aspect of the impact factor provides the greatest contribution or explains the increase, and if the increase is different in different disciplinary categories?

Open Source Science – Science and Sharing

Michael Nielsen’s talk at SciFoo’08:

Boston Globe on Open Science

Boston Globe has an interesting article about Open Science, citing the routine list of worries that usually get associated with this idea, e.g., :

But in the world of science – where promotions, tenure, and fortune rest on publishing papers in prestigious journals, securing competitive grants, and patenting discoveries – it’s a brazen, potentially self-destructive move. To many scientists, leaving unfinished work and ideas in the open seems as reckless as leaving your debit card and password at a busy ATM machine.

But, as John Hawks says:

I think that’s a pretty simplistic rendering of how scientific credit is assigned. It ignores all the factors that depend not on your results but on networking. Who you know may be vastly more important than what you do.
I think that if more researchers were independent (not tied to someone else’s lab) and if they spent less time grant-writing, we’d see more open collaborations. Right now the biggest barrier to openness is centralization.

Max Planck Society to support publication charges for PLoS journals.

This is big! A new agreement was signed between Max Planck Society and Public Library of Science in which the MPS will pay publication fees for its researchers. Mark Patterson explains:

The MPS is one of the world’s leading research organizations whose researchers have an international reputation for scientific excellence. We are delighted to be collaborating with the MPS in this way so that more MPS researchers will be encouraged to publish their work in PLoS journals, and to promote open access to research literature more broadly. For papers accepted in PLoS journals after July 1st, 2008, MPS will pay the publication fee directly to PLoS for all articles where the corresponding author is affiliated with a Max Planck Institute.
In 2003 MPS was the co-initiator of the Berlin Declaration on Open Access to Knowledge in the Sciences and Humanities and ever since then, MPS has demonstrated consistent and strong leadership in the promotion of open access to research results.
With the ever-expanding range of open access options available to authors, we encourage other research funders to set up funds to cover publication fees in open access journals or to include such expenses within their grants and research awards.

The Max Planck Society issued a press release about this as well:

In accordance with its commitment to ensure public availability of its research output, the Max Planck Society (MPS) has reached an agreement with the Public Library of Science (PLoS) for the central funding of publication fees of MPS scientists without burdening the budget of single Max Planck Institutes.
Like many Open Access journals, PLoS journals charge a fee for publication. For papers accepted in PLoS journals after July 1st, 2008, MPS will pay the publication fee directly to PLoS from central funds for all articles where the corresponding author is affiliated with a Max Planck Institute.
“PLoS is a top quality Open Access publisher. We are pleased to support a seminal publication model with this collaboration and thus facilitate publishing for our scientists in this interesting spectrum of titles”, said Ralf Schimmer, head of the Department of Scientific Information Provision of the Max Planck Digital Library.
PLoS is a nonprofit organization of scientists and physicians committed to making the world’s scientific and medical literature a freely available public resource. PLoS applies the Creative Commons Attribution License (CCAL) to all published articles. Under the CCAL, authors retain ownership of the copyright for their article, but allow anyone to download, reuse, reprint, modify, distribute, and/or copy articles in PLoS journals, so long as the original authors and source are cited. No permission is required from the authors or the publishers. Thus, the contents of the seven Open Access journals of PLoS are freely accessible for the reader worldwide via internet.
Collaboration for promoting Open Access
“The Max Planck Society is one of the world’s leading research organizations whose researchers have an international reputation for scientific excellence. We are delighted to be working with MPS so that more MPS researchers will be able to publish their work in PLoS journals, and for the broader promotion of Open Access to research literature”, said Mark Patterson, Director of Publishing at PLoS.
The research institutes of the Max Planck Society perform basic research in the interest of the general public in the natural sciences, life sciences, social sciences, and the humanities. As co-initiator of the Berlin Declaration on Open Access to Knowledge in the Sciences and Humanities (2003) MPS has actively supported change in scientific publishing in accordance with Open Access principles. MPS is advocating the position that research funding should include allocations for making research results freely available.”

How to get scientists to adopt web 2.0 technologies – Obligatory Reading of the Day

Eva Amsen: How to get scientists to adopt web 2.0 technologies:

Many, if not most, scientists are not in the habit of putting things online. The ones that are might be tempted by the concept of sharing the papers they read, letting everyone look at their lab notebook, joining a forum or writing a blog. If you’re reading this in your RSS feed or clicked through from FriendFeed, you’re probably one of those people. But think about your friends and colleagues who only turn on their computer for work and e-mail. They’re not going to tag their favourite papers or discuss the process of research with total strangers on the internet. It’s an extra thing to do that’s not already part of their lives, and no matter how appealing they might find the concept of open data or sharing information, they won’t join these sites or movements because it’s not something they are already doing.
So what are they already doing?

See also discussions on FriendFeed about this insightful article.
What do you think?

RSS Feed aggregator about Open Access

Tell Vedran what else should be included in the RSS Feed aggregator about Open Access….

Second Life and Social Media: Networking Gold Mine or Time Sink?

Elsevier steals, then copyrights other people’s free stuff

Reed Elsevier caught copying my content without my permission:

I was not asked for, and did not give, permission for my work to appear on that page, much less in that format. Needless to say, I felt a little slighted.
The website in question appears to be a custom version of the LexisNexis search engine. This particular version appears to be Elsevier’s own custom version, intended for internal use. I don’t have conclusive proof of that, but the title bar at the top of the page reads, “Elsevier Corporate”, and the person who accessed my blog from that page had an IP address that’s registered to MD Consult, which is an Elsevier subsidiary. My guess is that Elsevier’s keeping track of news articles and blog posts that mention them, along with the context in which they’re mentioned.

For-Profit Scientific Publishers and the Culture of Entitlement:

The relationship between publishers and the scientific community is not a partnership. It’s parasitic.
And it gets worse, because the parasite doesn’t even have the decency to try and hide what it’s doing. Instead, the major academic publishers seem to feel that they are entitled to continue to make enormous profits selling scientific research to scientists at outrageously inflated prices.
—————
Were it not for their track history, I suspect that neither the Mad Biologist or I would have been quite as irritated when they “borrowed” some of our work for internal use. With the track history, though, seeing our words sitting, without proper credit, permission, or attribution, on a page that bears a prominent notice protecting their copyright becomes something more. It goes from being a minor discourtesy to being another symptom of the company’s lack of respect for the people who do the bulk of the work to produce their profits, and provide the bulk of their customer base.

Reed Elsevier Is Stealing My Words:

I received an email from ScienceBlogling Mike Dunford that Reed Elsevier had excerpted one of my posts. No problem there–I like it when people read my stuff….except for one thing:
The fuckers copyrighted my words.

Copyright violation?:

Apparently, publishing companies don’t always get permission for the materials they use, either. Mike Dunford caught Reed Elsevier copying his content without permission (from Stephen Downes).

Elsevier’s New Open Access Policy…:

Although it is common practice within the blogosphere to quote liberally from other sources, we do this with the understanding that others may quote liberally from us. In fact, we hope that they will–as long as they give proper attribution. While we do this, our own material is made freely available, with running costs being paid for by advertisers (i.e., a pretty standard open access model) or just being footed by the blogger. Elsevier, on the other hand, not only reserves most of its material for paid subscribers, but actively fights the open access movement with insidious initiatives like PRISM.

Reed Elsevier Caught Copying My Content Without My Permission:

I’m including this link mostly because I’m not, you know, surprised. The stuff publishers want to ban us from doing is stuff they routinely do in-house, behind closed doors, where they think nobody will notice.

Elsevier Profits: $1,750 per minute – and growing? :

STM journal prices for the past few decades have risen far beyond inflation, and far beyond the ability of libraries to keep up. For long-term success, a business needs healthy, happy customers. This would also be a good success item to report, for Elsevier’s new Corporate Responsibility Division.

Open Access Wars, part n:

As they say, read the whole thing….

Free copyright license upheld Fed Circuit Court of Appeals

Larry Lessig reports some exciting, huge and important news: free licenses upheld:

So for non-lawgeeks, this won’t seem important. But trust me, this is huge.
I am very proud to report today that the Court of Appeals for the Federal Circuit (THE “IP” court in the US) has upheld a free (ok, they call them “open source”) copyright license, explicitly pointing to the work of Creative Commons and others. (The specific license at issue was the Artistic License.) This is a very important victory, and I am very very happy that the Stanford Center for Internet and Society played a key role in securing it. Congratulations especially to Chris Ridder and Anthony Falzone at the Center.
In non-technical terms, the Court has held that free licenses such as the CC licenses set conditions (rather than covenants) on the use of copyrighted work. When you violate the condition, the license disappears, meaning you’re simply a copyright infringer. This is the theory of the GPL and all CC licenses. Put precisely, whether or not they are also contracts, they are copyright licenses which expire if you fail to abide by the terms of the license.
Important clarity and certainty by a critically important US Court.

(Via, hat-tip)

Pushing Boundaries in Information Visualization

Pushing Boundaries in Information Visualization: Using Virtual, Immersive and Interactive Technologies in Research & Practice

Saturday, September 13, 2008
9am – 4:30pm
This workshop will showcase some of the innovative uses of technology in terms of virtual and immersive environments for interacting with information. The day’s events will generate attendee discussion around the use, integration and evaluation of such tools (how do we evaluate the use of these technologies? how can research improve practice? how can practice inform research, etc.).
The program will feature a colorful mix of research projects ranging from electrical stimulation of the nervous system with cochlear implant, to scalable visualization of genealogy links, experiential look at the death penalty, visualizing activity on a busy website, and comparing human and yeast cell protein interaction networks. Attendees need not be familiar with the disciplines of these research projects Ð the program will expose you to the use of immersive and interactive technology across a range of disciplines and then encourage discussion about the possibilities.
Event Details:
Saturday, September 13, 2008, 9am – 4:30pm
Renaissance Computing Institute (RENCI), UNC Campus – ITS Manning
211 Manning Drive, Chapel Hill, NC 27599
Free for ASIS&T members, $50 for non-members (ASIS&T student membership is only $40)
Payment must be received by September 8, 2008
Attendance is limited to 45

Discuss on Facebook.

Praxis #1 – last call for submissions

PraxisThe new blog carnival, covering the way science is changing (or not changing enough) in the 21st century – Praxis, is about to start. The call for submissions is now open – send them to me at Coturnix AT gmail dot com by August 14th at midnight Eastern so I can post the carnival on the 15th in the morning.
The business of science – from getting into grad school, succeeding in it, getting a postdoc, getting a job, getting funded, getting published, getting tenure and surviving it all with some semblance of sanity – those are kinds of topics that are appropriate for this carnival, more in analytic way than personal, if possible (i.e., not “I will cry as my minipreps did not work today”, but more “let me explain the reasons why I chose to work with advisor X instead of Y” or “how to give a good talk”, or “why publish OA” or “how does an NIH section work?”) and perhaps most importantly how the new technology – mainly the Internet – is changing the world of science. I expect a LOT of entries about Open Access, of course…. 🙂

When science bloggers publish, then blog about it ;-)

On Tuesday night, when I posted my personal picks from this week’s crop of articles published in PLoS ONE, I omitted (due to a technical glitch on the site), to point out that a blog-friend of mine John Logsdon published his first PLoS ONE paper on that day:

It’s a updated and detailed report on the ongoing work in my lab to generate and curate an “inventory” of genes involved in meiosis that are present across major eukaryotic lineages. This paper focuses on the protist, Trichomonas vaginalis, an organism not known to have a sexual phase in its life cycle.

Here is the paper (and check John’s post for his experiences publishing in PLoS ONE):
An Expanded Inventory of Conserved Meiotic Genes Provides Evidence for Sex in Trichomonas vaginalis:

Meiosis is a defining feature of eukaryotes but its phylogenetic distribution has not been broadly determined, especially among eukaryotic microorganisms (i.e. protists)–which represent the majority of eukaryotic ‘supergroups’. We surveyed genomes of animals, fungi, plants and protists for meiotic genes, focusing on the evolutionarily divergent parasitic protist Trichomonas vaginalis. We identified homologs of 29 components of the meiotic recombination machinery, as well as the synaptonemal and meiotic sister chromatid cohesion complexes. T. vaginalis has orthologs of 27 of 29 meiotic genes, including eight of nine genes that encode meiosis-specific proteins in model organisms. Although meiosis has not been observed in T. vaginalis, our findings suggest it is either currently sexual or a recent asexual, consistent with observed, albeit unusual, sexual cycles in their distant parabasalid relatives, the hypermastigotes. T. vaginalis may use meiotic gene homologs to mediate homologous recombination and genetic exchange. Overall, this expanded inventory of meiotic genes forms a useful “meiosis detection toolkit”. Our analyses indicate that these meiotic genes arose, or were already present, early in eukaryotic evolution; thus, the eukaryotic cenancestor contained most or all components of this set and was likely capable of performing meiotic recombination using near-universal meiotic machinery.

BioBarCamp is in session!

You can follow BioBarCamp virtually on FriendFeed and livecast!

Paperless Office? Bwahahahaha!

Today, I have everything I need on my computer, and so do most working scientists as well. Papers can be found online because journals are online (and more and more are Open Access). Protocols are online. Books are online. Writing and collaboration tools are online. Communication tools are online. Data collection and data analysis and data graphing and paper-writing tools are all on the computer. No need for having any paper in the office, right? Right.
But remember how new that all is. The pictures (under the fold, the t-shirt is of Acrocanthosaurus at the NC Museum of Natural Science) of my old office are only five years old! You know I am a Web junkie. If I could have survived without paper, I would have ditched it all. But I could not (and the pictures show only half of the office – there were two large file cabinets full of reprints behind the photographer – my brother – and much, much more, plus more in the lab itself):

Continue reading

In which I agree with Shermer on something….

Michael Shermer – Toward a Type 1 civilization. Ignore the nutty libertarianism – read only this sentence:

Globalism that includes worldwide wireless Internet access, with all knowledge digitized and available to everyone.

Web 2.0, Science 2.0, OA, etc.

There is a new study out there – Open access publishing, article downloads, and citations: randomised controlled trial – that some people liked, but Peter Suber and Stephan Harnad describe why the study is flawed (read Harnad’s entire post for more):

To show that the OA advantage is an artefact of self-selection bias (or any other factor), you first have to produce the OA advantage and then show that it is eliminated by eliminating self-selection bias (or any other artefact).
This is not what Davis et al did. They simply showed that they could detect no OA advantage one year after publication in their sample. This is not surprising, since most other studies don’t detect an OA advantage one year after publication either. It is too early.
To draw any conclusions at all from such a 1-year study, the authors would have had to do a control condition, in which they managed to find a sufficient number of self-selected self-archived OA articles (from the same journals, for the same year) that do show the OA advantage, whereas their randomized OA articles do not. In the absence of that control condition, the finding that no OA advantage is detected in the first year for this particular sample of journals and articles is completely uninformative.
The authors did find a download advantage within the first year, as other studies have found. This early download advantage for OA articles has also been found to be correlated with a citation advantage 18 months or more later. The authors try to argue that this correlation would not hold in their case, but they give no evidence (because they hurried to publish their study, originally intended to run four years, three years too early.)

How to do research – special free sample:

Key to doing research is having a discovery network in place to do the grunt work of navigating through the data smog for you. But even more importantly, constructing a discovery network is central to your professional formation, because it makes you ask yourself who you are and what sort of things you want to discover.
In many ways, your discovery network already discovers material out there and then evaluates it for you automatically, filtering through only the material you need. But the machine doesn’t know what you are working on at the moment, and of course is not as finally discriminating as your brain. So you need to filter the stuff your filters have been sending you. This is where the art comes in.

The confusion over data rights:

There was a time when I had the naive opinion that academics were all about the open dissemination of science, especially the sharing of basic scientific data. Alas, it turns out that for some the public domain is not exactly that. I suppose that this is a minority opinion, but it is clear that the confusion about scientific data and ownership needs to be resolved and fast. It should be obvious, but it isn’t and even those of us who should know better get confused. In the above case, if there was a paper where the data source had not been cited properly is understandable, but downloading and using sequences; Yowza!!!
There is a distinction between data and content/information. Too many people have trouble making the distinction and as a result there is confusion the ownership rights around the two. Anyway, this issue isn’t going anywhere soon it seems.

Virtual world interoperability:

As the number and variety of virtual worlds increases, so will the demand for interoperability. This will include not only teleporting between worlds, but also interworld communications, interworld asset portability, interworld currency exchange and many other issues. The technological aspects are an important part of this, and the public beta is an important step in the right direction. However, there are many social and business aspects that will also need to be addressed, and these may be even more difficult than the technological ones.

So open it hurts:

Web 2.0 visionaries Tara Hunt and Chris Messina blogged and twittered about their romance to all of geekdom as if it were one of their utopian open-source projects. Sharing their breakup has been a lot harder.

Five Life-Changing Mistakes and How I Moved On:

I’m out meeting with the press right now to promote SmartNow.com and I’m getting quite a reaction. Not to the business, but to me. You see, it’s been awhile since I met with them, at least eight years. Many of the people in the press are same ones I met all those years ago. Many I don’t know. No matter if they knew me before or not, they all ask the same question: “What mistakes have you made and what have you learned from them?” And this isn’t a normal “check-the-box” reporter question. This is a loaded question with heavy reference to my past, some would say my infamous past.
First some background, I was the CEO of Pets.com. In case you haven’t heard of it, Pets.com and its mascot, the Sock Puppet, became the symbol for the dotcom bubble and its subsequent bust. Some have even charged me personally with bringing down the U.S. economy. Pets’ short period of success was fueled by positive press about the company and myself. Pets received even more press when it failed.
As the public CEO, I failed, and it was a very public failure. In fact, I was labeled one of the biggest failures ever. How bad was it? I had people laugh in my face when I introduced myself for years after the company closed. It happened as recently as a year ago. A couple of people asked me what it felt like to be one of the best-known failures in the U.S. Most just walked away from me. One woman told me to my face that I was a loser. I could go on and on, but you get the point: I became a symbol for something greater than myself, and we aren’t talking puppet envy here.
What most people don’t know is that the very same week that Pets.com failed, my marriage of seven years failed as well. Actually, it had been failing for a long time. It became officially over that week. My husband decided to call it quits the day before I announced to the employees and the public markets that I was shutting down Pets. It was a really bad week…….

A Whole Lotta Thoughts On Blog Network Success (bonus tips included):

First, though, I want to enumerate some reasons why running a blog network, blog ad network or a blog “alliance” is harder than folk realize. But hopefully some of this post can help solve some of the stumbling blocks, as well as highlight the issues so folks go into these projects with eyes wide open.

Cuil: Why I’m trying to get off of the PR bandwagon…:

Journalists thrive off of conflict. That’s why we want a competitor to Google so badly and why we play up every startup that comes along that even attempts to compete with Google.
The problem is that competiting head on with Google is not something that a startup can do.

Open Access, but not really

Sometimes people ask me what do I have against Green OA (repositories) as opposed to Gold OA (journals) and I have a couple of stock answers to that, usually including a caveat that I do not really have anything against Green OA per se, but the way it is implemented is not good, yet makes people complacent, which in turn slows the down the progress towards complete OA. Not well implemented? Well, yes, I have seen all of these sins over the past couple of years. Once there is a standard that all builders of repositories adher to, Green OA will be OK (though there are other arguments against its current implementation still standing, i.e., the usual 6-12 month wait which is not inherent to Green OA but just a current bad practice).

The Web: how we use it

Best time to appreciate Open Access? When you’re really sick and want to learn more about what you have.:

* Complete OA still a long way off. One thing I re-learned during this was that it is incredibly frustrating to see how much of the biomedical literature is still not freely available online. Shame on Elsevier and all the others who are still hoarding this important information.
* Thanks to those providing OA. Related to the above issue, I came to appreciate was the societies and publishers have decided to go the OA route. I spent a lot of time reading material from ASM, BMC, PLoS, Hindawi, and a few others. And I am grateful to these groups.
* Google rocks for science searching. Cuil, not so much. If you need to find something about some scientific concept or issue, Google really does a great job. While I was out, Cuil was announced as a possible new competitor for Google in searching. From my experience, Cuil is really really lame for science searches. I like their presentation in a magazine style. But the search results were not so good.

Free Microsoft tools for scholarly communication:

* This is for real. Don’t mistake the Microsoft research division, which doesn’t sell anything, for the Microsoft product divisions. Tony Hey believes in open access and open data, and is putting Microsoft resources behind them. For background, see Richard Poynder’s interview with Tony Hey (December 2006), and my previous post on the Microsoft repository platform (March 2008).
* The new tools are free of charge. The announcement doesn’t say they will ever be open source, but Microsoft encourages open-source tools in the open chemistry projects it funds. So it’s possible.
* The authoring add-in should help publishers (including OA publishers) reduce costs, at least if they want to provide XML, and it should help them decide to use XML. The repository platform and e-journal service are even more direct contributions to OA. I don’t know much about the e-journal service, apart from a swarm of great ideas raised at a Microsoft brainstorming meeting in November 2005. And I don’t know much about the repository platform except that it will be interoperable, play well with Microsoft tools like SQL Server Express, use semantic processing to create arbitrary relationships between resources, and serve as a back end compatible with DSpace and EPrints front ends. I look forward to user reviews.

Nature Publishing Group launches Manuscript Deposition Service:

Nature Publishing Group (NPG) today launches the first phase of its Manuscript Deposition Service. The free service will help authors fulfil funder and institutional mandates for public access.
From today, the NPG Manuscript Deposition Service will be available to authors publishing original research articles in Nature and the Nature research journals. NPG expects to be able to announce the availability of the service for many of its society and academic journals, and for the clinical research section of Nature Clinical Practice Cardiovascular Medicine, shortly.

Who Writes Wikipedia?:

“When you put it all together, the story become clear: an outsider makes one edit to add a chunk of information, then insiders make several edits tweaking and reformatting it. In addition, insiders rack up thousands of edits doing things like changing the name of a category across the entire site — the kind of thing only insiders deeply care about. As a result, insiders account for the vast majority of the edits. But it’s the outsiders who provide nearly all of the content.”

On information overload:

Over the last few months I have witnessed a steadily growing stream of writers declaring news feed, blogging and/or social media bankruptcy, citing such things as information overload, hobbies becoming ‘work’ or even the fact that so many people on the internet can be jerks about such small things.

Gene Wikiality:

Still, for the gene wiki to become what the researchers envision, they’ll need informed people — lots of them — who are willing to log in during a coffee break or three, check out an entry or two, and make necessary edits and additions. They’ve built it; it’s time to see if the scientific community will come.

The passionates vs. the non passionates (definitely also check the discussion on FriendFeed):

“….Some things that I’ve noticed about late adopters (er, non-passionates) and how they use computers they really are much different than the passionates who I usually hang out with. They really don’t care about 99% of the things I care about. FriendFeed? Yeah, right, they haven’t even heard of it, and if I try telling them about it, they say “why would I do that?” See, most people just want to work their 9 to 5 jobs, go home, pop open a beer, sit on the couch, watch some movies, play with their kids, etc.
Stay up all night talking to strangers? No way, no how. Most of the non-passionates I know are just barely trying out Facebook (90 million users). Twitter? Yeah, right. (Two million).
Heck, these people don’t even know how to use an address bar in a browser. Think I’m kidding? I’ve watched how normal people (er, non-passionates) use computers. You go to a search box, and type “Yahoo” even if you are already on Yahoo. Think I’m kidding? Ask the engineers over at Yahoo how many times a day people search for Yahoo on Yahoo’s own search engine. Same over at Google.
When I travel, I look at what people use — thanks to being on planes a lot in the past few months I get to see what people use. Most are using technology I used back in 2000. That’s eight years ago, or 100 in Internet years. I look at them the same way you’d look at them if they told you they just started using a telephone.
The exception? Blackberry. But show me a Blackberry user that knows how to look up Google Maps or uses the Web more than once a week? I’ll show you a passionate. I’ve talked to hundreds of people in airports and I haven’t found a Web-using Blackberry user yet that’s not a passionate (meaning, someone who is really passionate about technology).
And let’s not forget the fact that of the six to seven billion people in the world only about a billion even have a computer in the first place. So, that means that five to six billion people really don’t care about Windows or OSX or all that.
We can be so arrogant sometimes to forget that there are more people who are NOT like us, than who are like us in the technology world……”

Passion, Early Adopters and the Mainstream:

Sometimes I wonder whether people have forgotten why we do what we do. Most people who blog do it because they have a passion for what they are writing about. Many people creating these fancy Web 2.0 sites are doing it because there is some passion for what they are doing. Even “how to be successful” guides highlight that you should have passion for your work if you want to be successful. Given this need for passion, I find it interesting that people are trying to focus on the mainstream users. Granted, the big reason for this is massive traffic and huge revenue, but how do you get there? You have to start somewhere, right?

Passionates:

The activity is the thing to focus on, not the technology. Technology enables the activity, and people will get excited about the technology if they’re excited about the activity first and the benefits of the technology has been explained to them. But you don’t make passionate photographers by showing them lenses, you make passionate photographers by showing them pictures that rip your heart out.
That said, I understand the point Robert is making. There are some people (early adopters) who will try out anything simply because it’s new and interesting. But those are technology early adopters…a very small population of people who get a large amount of attention because of their predilection to try new things. A much larger population (although much more fractured) are those people who are already passionate about some activity or other, and can become passionate about new technology as it relates to that activity, but they just haven’t been introduced properly.

Correct. I am a technological Luddite. I barely use HTML and would not recognize any kind of code if it hit me in the face. I have had a cell-phone (not an iPhone!) for a year now and I barely use it. I never got a Blackberry. My iPod-Touch is still in its box two months after I got it. I do not check e-mail or Web on anything smaller than a laptop. I do not regularly read tech blogs (except an occasional post about social aspects of the Web). I am not interested in the newest shiny thing. Technology itself does not excite me, it is what I can do with it. I usually wait for the Darwinian process to work out its magic first, then adopt the winners, once forced into it because everyone else is using it and expects me to use it, too.
I use Dopplr to meet people who travel (or when I travel). I have a profile on LinkedIn only because everyone else does – I never check it. I have logins elsewhere mainly so I can check where the links are coming from to my blog (e.g, Digg, Stumbleupon, Flickr….). I never signed up for Twitter as it does not do anything I need it to do. And that is it.
But I was an early adopter of blogs, because my blog let me shout and be heard and get feedback. I was an early adopter of Facebook, when it got started some years ago, but I have tested and deleted most of the apps there – I use it for only a couple of things (and those come via e-mail notifications) so I do not spend time on it. I am an early adopter of FriendFeed because it is a great source of good links, filtered by people who are interested in the same things I am. I am an early adopter of Open Access evangelism because I lost my library access privileges at the University and could not get the papers to blog about. If I were still doing science, I’d be using CiteULike probably, but not most of the myriads of other “science social networks” that are springing up seemingly every day. We all have our own passions and our own needs.

Carnival of Science/Academia/Publishing?

Martin saw this comment of mine and sprung into action: Name the new ‘Carnival of Scientific Life’!

The two big questions are what to call it, and how often to host it, so I’d like your input in the comments below please. I’ll be making the final decision on August 1st.
What would be a good name for the carnival? (Ideally something without “carnival” in the title.)
Should it be held monthly, or at some other frequency?
The carnival is intended to cover all aspects of life as a scientist, whether it’s the lifestyle, career progress, doing a Ph.D., getting funding, climbing the slippery pole, academic life as a minority, working with colleagues and students, dealing with the peer-review process, publishing, grants, science 2.0, amusing anecdotes, conference experiences, philosophical musings, public engagement, or even historical articles about what life was like in the good (or bad) old days.
In other words, anything related to the experience of living the scientific life. Not blogging about research, but blogging about everything that goes with being a researcher. A sort of “meta-science” carnival if you like.
I’ll be putting together a hosting schedule here in the coming days. If you’re interested, let me know at editor@layscience.net.

This is how he describes it: About the Carnival of Academic Life

The carnival is intended to cover all aspects of life as an academic, whether it’s the lifestyle, career progress, doing a Ph.D., getting funding, climbing the slippery pole, academic life as a minority, working with colleagues and students, dealing with the peer-review process, publishing, grants, science 2.0, amusing anecdotes, conference experiences, philosophical musings, public engagement, or even historical articles about what life was like in the good (or bad) old days.

On the same day, there was a thread on ‘Plausible Accuracy’: Open Science blog carnival – The interest seems to be there, so what about the details?, where I left the following comments:

I’ve seen carnivals come and go, and at this point I do not think there is enough people out there to sustain a carnival on such a narrow topic as OA alone. I would rather have a carnival on all things meta-science, with an OA section in it.
———-
This also means that people who write/read about other aspects of life in science will get to read the OA stuff (people always check out who else is on the carnival they are in, and also link to the carnival), many for the first time, and get introduced to the idea which they can spread to others. Makes the topic less insular when it rubs shoulders with others who write about science but never gave a thought to the business of publishing before. A way to bring in more people to the cause.

I would think that something like this would be OK. Not “I am bummed because my mini-prep did not work today” kinds of posts, but analytic posts about the way science works, the way academia is organized, the internal and external politics of science, discrimination, funding, promotion, careers, the business of publishing, the Science 2.0 and science blogging issues, etc., but with a special emphasis on the way the Web is changing science practice in all of its aspects.
What do you think?

Today in OA

Citation Statistics (pdf):

This is a report about the use and misuse of citation data in the assessment of scientific research. The idea that research assessment must be done using “simple and objective” methods is increasingly prevalent today. The “simple and objective” methods are broadly interpreted as bibliometrics, that is, citation data and the statistics derived from them. There is a belief that citation statistics are inherently more accurate because they substitute simple numbers for complex judgments, and hence overcome the possible subjectivity of peer review. But this belief is unfounded.

Information Liberation:

If your child has a life-threatening disease and you’re desperate to read the latest research, you’ll be dismayed to learn that you can’t — at least not without hugely expensive subscriptions to a bevy of specialized journals or access to a major research library.
Your dismay might turn to anger when you realize that you paid for this research. Through the National Institutes of Health alone, American taxpayers funnel more than $28 billion annually into medical research. That’s leaving aside the billions more in public spending on state universities or the tax exemptions granted for gifts to private campuses.

Open Access and the NIH

In 1978, in enacting Section 105 of title 17, Congress faced a choice about what to do with copyrighted works that result from government funding, including basic research funding of scientific, technical, and medical (“STM”) journal articles. One approach was simply to preclude any assertion of copyright, treating such works the same way as works created by government employees within the scope of their employment. That approach would have been simple to apply, but might have inhibited the publication of some STM journals, at a time when hard copy ruled as the method of distribution. Congress chose a middle approach, discussed here in the 1976 House Judiciary Committee report:, which begins by referring to the definition of “work of the United States government”:

An Interview with Heather Joseph:

Heather Joseph talks about her career with SPARC and BioOne. She discusses the NIH mandate that NIH-funded research will be deposited into PubMed Central, and she shares her views on some of the controversial issues the mandate has raised about copyright, peer review, and embargo periods. She also addresses the recent decision by the Harvard faculty to make their scholarly output accessible through the university’s institutional repository, and she suggests ways that librarians can help their faculties prepare for open access.

Heather must be dismayed that her interview is behind the pay-wall.

Podcast on Open Science

Watch it here:
The Extraordinary Everyday Lives Show #053 – Open Science:

This show is all about the intersection of Technology and Human desire. This year Dave and I have been focusing on ‘deepening connections’ with those we subscribe to via RSS. Having a chat on a podcast is a remarkable way of doing that we have found. Agenda is loose guide only, we are very stream of consciousness, no edits, no script kinda guys.

In(s) and Out(s) of Academia

Bjoern Brembs is on a roll! Check all of these out:
Incentivizing open scientific discussion:

Apart from the question of whether the perfect scientist is the one who only spends his time writing papers and doing experiments, what incentives can one think of to provide for blogging, commenting, sharing? I think because all of science relies on creativity, information and debate, the overall value of blogging, commenting and sharing can hardly be overestimated, so what incentives can there be for the individual scientist?

Journals – the dinosaurs of scientific communication:

Today’s system of scientific journals started as a way to effectively use a scarce resource, printed paper. Soon thereafter, the publishers realized there were big bucks to be made and increased the number of journals to today’s approx. 24,000. Today, there is no technical reason any more why you couldn’t have all the 2.5 million papers science puts out every year in a single database. It doesn’t take an Einstein to realize that PLoS One is currently the only contender in the race for who will provide this database. For all the involved, it is equally clear what the many advantages of such a database would be. Consequently, traditional publishers are rightfully concerned that their customerbase is slowly dissappearing.

Post-publication paper assessment:

The more variables there are to game, the more difficult it becomes. Now we have one variable (IF) and we all know who is gaming it ad nauseum. In this thread we have 5 measures, add ratings and comments and you have 7. This should be impossible to game for anyone but the hacker who can get thousands to machines on the net to just hype this one paper.
All of these measures are relevant even long after publication. Some papers ignored by the media may later turn out to harbor the most important discovery of the century, while some of those tossed around everywhere turn out to be completely irreproducible. Having these measures in place, if nothing else, would allow us to quantify and study such events.
But again, no matter how many numbers you have, these measures cannot substitute for actually reading the papers! The numbers barely give you a rough idea of where a paper or a scientist can be placed with respect to others in the same field. Yet, these measures would be light-years ahead of any one-dimensional, irreproducible, obviously manipulated and corrupt measure such as the IF.

Building a scientific online reputation:

For me, this basically means that all the expertise and technical prerequisites are there to bring the scientific community into the 21st century. The advantages of the new system need to be succinctly summarized and widely publicized at the same time as the current system’s disadvantages and idiosyncracies need to be pointed out and publicized along with the new proposal. And because criticizing is always easier than advertising, I’ll start by summarizing why Thomson’s Bibliographic Impact Factor (BIF) is dead.

Why Thomson’s Bibliographic Impact Factor (BIF) is dead:

Despite the recent downpour of evidence against the use of Thomson’s BIF, I still get comments from people such as “However, IFs are still the most used way of evaluating a researcher’s career and value. Even if we find this ridiculous, it’s just the way it is.” or “in our institution, every researcher has to publish in journals whose BIF is at least 5.”. In the light of the current state of affairs concerning the BIF, this is just embarrassing. So here are the top three reasons why the BIF is dead:
1. The BIF is negotiable and doesn’t reflect actual citation counts (source)
2. The BIF cannot be reproduced, even if it reflected actual citations (source)
3. The BIF is not statistically sound, even if it were reproducible and reflected actual citations (source)
Now go and spread the information so I don’t have to suffer from these ridiculous statements any more.

Then, on Nature Network blogs and Nature blogs, discussion about the “manners” in the science blogosphere:
Corie Lok: What is fair play in the blogo/commentosphere?:

Now, maybe it’s a generational thing. Those of us who didn’t ‘grow up’ with blogs might be more easily taken aback by what goes on in them. Those of us who did grow up with them perhaps have learned to take the bad with the good.

To which I commented:

A lot depends on one’s prior experiences. If one comes to science blogging out of academia with its highly formalized and ritualized kabuki dance of language-use, extremely polite on the surface, yet often very vicious in the subtext, then one sees blogs as very uncourteous and unpleasant – the things that are supposed to be hidden between the lines and now said openly.
Many of the most popular science bloggers have a different history – many years of battling Creationist and other pseudoscience crusaders on Usenet groups in the early 1990s, people who, if they can use language at all, use it in a very vicious way, sometimes with threats of bodily harm. I spent the early 90s on Balkans usenet groups, battling heatedly nationalist Serbs, Croats and Bosnians who do not just voice empty threats but would, if they could find you, really kill you. Others cut their teeth on political blogs or feminist blogs, which are very blunt and heated. Just try not supporting Howard Dean in the 04 primaries or Obama in 08 – you get your fill of human nastiness. And that is nothing compared to what Republicans say once the general election starts!
My first blog was political – I wrote highly opinionated and strongly-worded posts. And of course, I got, let’s put it diplomatically, some highly opinionated commenters. I never deleted. Sometimes I responded (politely at first – that is unusual and disarming – I turned some trolls into friendly and polite commenters that way), sometimes I ignored, sometimes my other commenters took care of trolls.
Then, after the move to Sb, I gradually reduced writing about politics and religion and my threads are now quite nice and polite most of the times. Various heated debates about “framing” or the latest “Nature vs. PLoS” kerffufle are sweet lullabies compared to most of the stuff I saw and suffered over the years online. One grows a thick skin, understands that people behave strangely online, laughs at the most egregious examples, and moves on.
There is no single definition of a “science blog”. Blog is a piece of software. You do what you want with it. If you are a scientist with a blog, or if you write more-or-less regularly about science (or meta-stuff, e.g., life in the lab, women in academia, politics of science funding….), then you can claim that your blog is a science blog. And your blog is going to be different from all other science blogs out there, as it is what you want it to be, reflecting your own interests, goals and personality. Nobody can tell you how to do it. There is no, and there should be no “template” or “definition” of a science blog – that is the beauty of the beast.
Thus, some blogs are serious, others not. Some are nice, some are inflammatory. Some focus 100% on latest peer-reviewed research. Others are a smorgasbord of everything the blogger feels like posting at any given time (like my blog, for instance). There is no recipe, no straightjacket, no “one right way” to do it. And that is what makes the science blogosphere so exciting and vibrant – so many cool voices, interesting personalities! Who says that scientists are socially-inept or bad communicators?!

The discussion there continues:
Noah Gray: Getting into and out of character:

We seem to be at a critical juncture concerning the intersection of blogs and other Web 2.0 technologies with science. This is no time to poison the atmosphere and turn away the more “relaxed” or “casual” participants. Polarized communities refusing to tolerate rival positions, or unwilling to engage in a civil debate over any topic, from publication business models to the role of Ca2+-permeable AMPARs in LTP, will shut out many would-be contributors and stunt the growth or slow the adoption of blogs, commenting, and other web-based technologies dedicated to the pursuit of scientific collaboration. If such technologies are ever really going to work for science, it will be because of inclusivity, not exclusivity.

Maxine Clarke: Manners in the blogosphere:

The anonymity of cyberspace provides protection to both share honest opinions and participate in mud-slinging without repercussion, he notes. Yet interaction on the Internet is more personal. “So why should some choose to check their manners at the door before logging on?” He argues that intolerant online communities unwilling to engage in a civil debate — whether on publication business models or the role of glutamate receptors in long-term potentiation of neurons — will turn off would-be contributors and stunt the growth of online scientific collaboration. Web-based collaborative technologies will not work for science if they become dominated by exclusive, aggressive types. Gray isn’t calling for “communal singing of Kum Ba Yah during scientific debates”, but simply a certain level of restraint and professionalism online.

This is an interesting segue to Michael Nielsen’s latest instalment of his future book about the future of science: Shirky’s Law and why (most) social software fails:

Shirky’s Law states that the social software most likely to succeed has “a brutally simple mental model … that’s shared by all users”.
If you use social software like Flickr or Digg, you know what this means. You can give friends a simple and compelling explanation of these sites in seconds: “it’s a website that lets you upload photos so your friends can also see them”; “it’s a community website that lets you suggest interesting sites; the users vote on submissions to determine what’s most interesting”. Of course, for each Flickr or Digg there are hundreds of failed social sites. The great majority either fail to obey Shirky’s Law, or else are knockoffs that do little not already done by an existing site.
To understand why Shirky’s Law is important, let’s look at a site where it’s violated. The site is Nature Network, one of the dozens of social networking sites aspiring to be “Facebook for scientists”. Like other social networks, Nature Network lets you connect to other users. When you make a connection, you’re asked whether you would like to connect as a “friend” or a “colleague”. Sometimes the choice is easy. But sometimes it’s not so easy. Furthermore, if someone else connects to you, you’re automatically asked to connect to them, but given no immediate clue whether they connected as a friend or as a colleague. The only thing shared in the users’ mental model at this point is acute awkwardness, and possibly a desire to never connect to anyone on Nature Network again.
I don’t mean to pick on Nature Network. It’s the most useful of the social networks for scientists. But it and most other social websites (apart from the knockoffs) don’t even come close to obeying Shirky’s Law.
Why is Shirky’s Law so hard for developers to obey? I’ll give three reasons.

Interesting…. We here at Sb are often accused of being cliquish and insular. But if you look at our 70+ blogs and dig through the archives, you will see that we rarely comment on each other’s blogs – most (99%?) of the comments come from outside readers. Also, most of our links point to outside of Sb. On the other hand, NN is specifically designed to be a community (not a platform for independent players) and almost all of the comments there are from each other. Thus, it is easy for them to maintain a high level of politeness there (this is not a bad thing – this is how they designed it on purpose). It is much harder to harness the hordes of pharyngulites that spill over to all of our blogs – and I do not mind them at all, I think they make the debate spirited and in a way more honest by bypassing superficial niceness and going straight to the point. This may also have something to do with NN bloggers mainly being in the academia, while a large proportion of SciBlings are ex-academia, journalists, artists, etc. with a different rhetoric. The rhetoric of academia is a very formalized kabuki dance, while the rhetoric of the blogosphere has shed all formalities and is much more reminiscient to the regular everyday oral conversation.
Moving on to other, related topics…
Jocalyn Clark: Is the NIH open access policy regressive?:

Panellists noted that the recent NIH public access policy emphasises free not open access. That is, the policy may lead to freely accessible publications (for which publishers or organisations may reap profits from charging authors a fee to deposit their manuscripts), but these will remain under restrictive licenses (thus limiting text-mining).
This, Cockerill argued, makes the NIH policy regressive.

NASA to launch OA image collection:

Nasa is to make its huge collection of historic photographs, film and video available to the public for the first time.

Rhea Miller: Vow to never become Jaded…:

But I do NOT understand why it is socially accepted to be a Jaded student…to be completely negative about the research he/she does, to avoid showing up to journal clubs/seminars, or to never participate in scientific discussions. What does being burnt out do for you in becoming the best you can be?? How does it help your science, your field, or your coworkers??
I really only notice these attributes in young scientists, i.e. graduate students and post-docs. Does this mean that the Jaded ones eventually give-up, get use to it, change their prospectives, or do they hide that inner Jaded color as they progress?? Or maybe it’s just that grad students/postdocs can’t seem to see the light at the end of the tunnel until they get there??

Panthera studentessa: Letting fear take over:

As time goes on, I’m becoming more and more concerned that I don’t have what it takes to hack it in graduate school. In every community, every blog, every forum that I read, people always talk about how stressful and all-consuming grad school is. To be perfectly honest, my mental health isn’t exactly the best it’s ever been. I just worry that I won’t be able to handle the mental and physical stress.
——-
I suppose there’s always the option of just not going to graduate school, but that really throws a wrench in my career plans. I don’t even know what kind of jobs a person can get with a bachelor’s in zoology. And anyway, I don’t want to let my fear determine what I do with my life. I just wish I knew how to begin to get over it.

Maddox2: Advice on Freelance Science Writing:

Caveat: I am writing this advice from the perspective of an editor who regularly works with freelance science writers. However, the market in which I work may not be the same as some of you out there work in, or want to work in. Therefore, I can guarantee that following the advice below will endear you to K-12 educational publishers (and to companies like mine who work for educational publishers). I can’t speak to journals, newspapers, etc…but I can’t imagine they’d mind if you follow this advice! And given that a lot of people here have expressed an interest in freelance writing, I thought I might be able to provide a bit of a different perspective on things.

Mad Hatter: Networking Nuts And Bolts:

I think the most important thing to keep in mind when networking is that your contacts are much more likely to help you if they like you. My personal philosophy on networking is this: when my networking contact turns on her computer and sees an email from me, I want her to click on the email thinking, “Hey, I remember Mad Hatter. I liked talking to her. I wonder what she’s been up to?” What I don’t want her to do is groan and think, “Oh, no…it’s Mad Hatter again. What does she want now?” So with that in mind, here are some tips on networking that have worked for me.

John Hawks has posted first two of a 4-piece series on Blogging And Tenure: How to blog, get tenure and prosper: Starting the blog:

Last month, the University of Wisconsin officially granted me tenure. So, I can say without any doubt (if other examples had not been sufficient), it is absolutely possible to write a daily, high-profile blog and still be recognized by your colleagues as a scholar. In fact, it is possible to blog, do good research, and earn tenure at a Research I university.
That seems like progress, compared to the situation four years ago when I began blogging. A few high-profile tenure denials in late 2005, including physicist Sean Carroll and political scientist Daniel Drezner, made it seem like a blog might be the kiss of death for a research reputation. Inside Higher Education ran a story on the subject, as did Slate, with the melodramatic title, “Attack of the Career-killing Blogs”. Since I was interviewed in that article, I suppose I should have been a little nervous (I wrote about it here).
Happily things have changed.

…and: Graduate students and blogging:

As far as I know, there are no data concerning blogging and career success — or, for that matter, between any kind of public outreach and success in research careers (as opposed to teaching or industry careers that directly involve outreach). Anecdotally, there are some people who spend a lot of effort on outreach who have very well-respected research careers, and others who don’t. I’d say it’s up to the individual to chart her own course.
——————–
I’d like to advocate for a model of blogging that many graduate students might find useful. If I were starting out today, I’d blog my dissertation. Why not? Is there really anything so secret in your history and literature review that it couldn’t be read by the few hundred people who will find your blog?

New in: Open Access and Science 2.0

The complexity of sharing scientific databases:

Under US law, pretty much anything you write down is copyrighted. Scrawl an original note on a napkin and it’s protected until 70 years after your death. Facts, however, are another matter – they can’t be copyrighted. So while trivial but creative scribblings are copyrighted, unless you choose to release them into the public domain, the information painstakingly discovered about the human genome – DNA sequences, for instance – aren’t. But the containers they’re stored in – the databases they’re held in – can be copyrighted.

Breaking News: Open access to large-scale drug discovery data at EBI:

The Wellcome Trust has awarded £4.7 million to the European Bioinformatics Institute (EBI) to support the transfer of a large collection of information on the properties and activities of drugs and a large set of drug-like small molecules from BioFocus DPI, part of the publicly listed company Galapagos to the public domain.

What scientists are we talking about?:

This discussion seems to have focused on just a small fraction (but an important one) of the number of scientists who would benefit from these tools. These researchers are funded by grants and are in tenure-track positions at 4 year research universities.
More scientists work at non-profits. What sorts of pressures are brought to bear there to prevent open collaboration? How different are these pressures from a research university? Those in business might also benefit from these approaches but have another set of barriers. Can they be surmounted?
This discussion is really important but it also conflates a large number of scientists/engineers who have different needs and pressures. There are 12 million in business who will have different needs than the 1.6 million at research universities.

MedPedia Is Wikifying the Medical Search Space:

The medical industry is one that thrives on innovation and evolution. New procedures, medicines, diseases, and theories are released practically every day. In such an environment, the need for a website to reflect and allow for documentation is apparent.

Open Access to Health and Human Rights:

Here’s another important step forward in the open access movement. Under its new editor Paul Farmer (who is often talked about as a future Nobel laureate), the international journal Health and Human Rights (HHR) has become fully open access.
The entire contents are freely available and are published under a progressive copyright license that allows readers to reuse the materials for any legal non-commercial purpose.

Indexing Institutional Repositories and Authors Self-Archived Collections:

The question then is whether or not ChemSpider can index institutional repositories or authors self-archived collections on their university research group websites. The authors self-archived collections will be very valuable but of course most likely to upset the publishers. We’d like to do both.
I envisage a time when articles are indexed and searchable even before they are published and indexed by others. Why not? If there are changes to the article between pre-and post-publication both can be indexed.

Another Wiki, WikiPathways:

I’ve already made known my “skeptical optimism” for wikis for biological data known in a previous post, reading this later paper, that would still apply here. But right now I’m not going to write beyond that, I’m just going to point you to this paper and wiki. Later (this week, next at the latest) I’ll be critiquing this paper more fully and more generally look at this trend currently to use wikis for community curation and documentation of biological data and databases.

Tracking the openness of databases:

Shirley Fung has launched Molecular Biology Databases, a website to evaluate the openness of databases in molecular biology.
———
Fung evaluates 34 databases to date, under six criteria: Downloadable, Offers Batch Processing, Offers a Query Interface, No Registration Required, Policy is Available, Public Domain. Her website supports the open-data research of Melanie Dulong de Rosnay, described last week by Ethan Zuckerman (and blogged here).
This is a very time-consuming but useful job. Everyone in molecular biology should be grateful, especially if the project leads to more consistent policies on open data across the field.

Fair game: a grad student’s adventures in fair use and copyright:

For scholars who study media, the internet has broadened research horizons and expanded the reach of teaching and publications. But powerful gatekeepers remain. From academic journals seeking to control our intellectual property to lawyers crying foul when we quote from copyrighted material, we are bombarded with a myriad of confusing and dubious restrictions. In short, the implied threat of legal action creates a chilling effect that impacts us all. Some have pushed back, arguing that our educational activities are protected under the “fair use” statute. But this is a risky game to play. The rules aren’t always clear. And when it comes to fair use, we either use it, or lose it.

Where should we spend our money?:

The lesson here seems to be that the digital environment is inevitably going to change the environment for textbooks as it has for most other kinds of intellectual property, for good or for ill. Georgia seems to feel that the publishers will eventually figure the market out and move to new profit models while supporting open access. But I think there is also an opportunity here for institutions to be more proactive and seek ways to invest in open access textbooks on a campus-wide level.

STM publishers imprisoned in their own walled gardens?:

Journals aggregate interesting science – many scientists still very much like a group of qualified editors and peer reviewers providing a filter on the deluge. Secondly, while knowledge discovery requires unfettered access for machines to content, I don’t see why that necessarily implies unfettered access for humans. You can perfectly well have an API that lets machines mine full-text, while still putting up a paywall for humans. As well, I think the versions issue is very challenging, and we are a long way from reliable automatic disambiguation and identification of authoritative copies. Finally, many conference proceedings already are peer-reviewed, and we can certainly imagine peer review extending to other areas, such as data sets.

History of the Journal Nature:

Nature introduced their formal peer review system in… 1967!

Who comments on scientific papers – and why?:

The quality of comments at BMC is high and the vast majority add value to the paper, though the numbers involved are relatively low (would a larger audience reading higher impact papers be different?).
Perhaps unsurprisingly comments on papers are not like comments on blogs; they’re far more formal (only 8% of comments were of the chatty, supportive variety) and it’s not the same people coming back each time (with the exception of the crazy 2%).

Vedran Vucic on Open Access

A couple of weeks ago, Vedran Vucic gave a talk about Open Access at the law school at the Belgrade University. For those of you who can read Serbian, here is the newspaper report. Glad to see PLoS mentioned…

Journals – the dinosaurs of scientific communication

Bjoern Brembs:

Today’s system of scientific journals started as a way to effectively use a scarce resource, printed paper. Soon thereafter, the publishers realized there were big bucks to be made and increased the number of journals to today’s approx. 24,000. Today, there is no technical reason any more why you couldn’t have all the 2.5 million papers science puts out every year in a single database.
——–snip——–
Precurser to this publishing reform was access reform: scientific papers are the result of publicly funded research and should be publicly accessible. This reform appears now to be well underway and will probably conclude in 2-3 years. Both reform movements have their base in the more general open science movement. The goal of this reform movement is to have full public access not only to the published papers, but also to the raw data, ideas and reagents for sharing among scientists. There are still plenty of problems which have to be worked out before open science can become a reality, if it is even feasible. One of the more easy to solve problems (one that is shared with publishing reform) is that of how to attribute credit. If we all publish in the same database and share ideas online, how can two scientists competing for the same position or grant be assessed objectively?
——–snip——–
Different universities/employers will focus on different aspects of a researcher and value some of his/her contributions more than others. I don’t think there can be too many measures to capture the complexity of scientific output. I’d like to see an aggregating service, maybe based on services like OpenID, where a flexible portfolio can be organized such that employers can easily search for the traits they are looking for and find or compare the people who maximize their efforts on these traits.
——–snip——–
I think most researchers would gladly pay for a service which has a track record of picking the most interesting, groundbreaking and well-done papers from the 2.5 million every year. Today’s professional editors would be a great pool from which such services could recruit employees.

Electronic Publication and the Narrowing of Science and Scholarship. Really?

Electronic Publication and the Narrowing of Science and Scholarship by James A. Evans, ironically behind the paywall, has got a lot of people scratching their heads – it sounds so counter-intuitive, as well as opposite from other pieces of similar research.
There is a good discussion on FriendFeed and another one here.
A commentary at the Chronicle of Higher Education is here, also ironically behind the paywall.
Here is the press release and here is the abstract:

Online journals promise to serve more information to more dispersed audiences and are more efficiently searched and recalled. But because they are used differently than print–scientists and scholars tend to search electronically and follow hyperlinks rather than browse or peruse–electronically available journals may portend an ironic change for science. Using a database of 34 million articles, their citations (1945 to 2005), and online availability (1998 to 2005), I show that as more journal issues came online, the articles referenced tended to be more recent, fewer journals and articles were cited, and more of those citations were to fewer journals and articles. The forced browsing of print archives may have stretched scientists and scholars to anchor findings deeply into past and present scholarship. Searching online is more efficient and following hyperlinks quickly puts researchers in touch with prevailing opinion, but this may accelerate consensus and narrow the range of findings and ideas built upon.

For now, let’s see what others say:
Peter Suber:

* It’s hard to say much based on a newspaper summary and a press release. But at first glance, Evans’ results conflict with the many studies showing that OA articles are cited significantly more often than non-OA articles. These studies differ from one another on how to explain the correlation between OA and increased citation counts, but they agree on the correlation. However, there may be ways to reconcile the two sets of results. For example, authors may cite fewer articles when they have more to choose from, but they may still cite OA articles relatively more often than TA articles. Or the average number of citations per article may decline with the growth of the total number of articles accessible to authors, but OA articles might bring the average up, and TA articles might bring it down. Or the multiplication of ejournals may be narrowing the scope of the average paper, and therefore shortening the average reference list, but citations may be growing overall and the of citations of OA articles may be growing faster than the citations of TA articles. (On the other side, the Economist said that “the same effect applied whether or not a journal had to be paid for” –though without specifying exactly which effect.)
* Evans’ results also appear to conflict with a recent study by Arthur Eger, Database statistics applied to investigate the effects of electronic information services on publication of academic research – a comparative study covering Austria, Germany and Switzerland, GMS Medizin – Bibliothek – Information, June 26, 2008. Eger found that “a larger content offering coincides with a dramatic increase in Full Text Article requests, and an increase in Full Text Article requests, after about 2 years, coincides with increased article publication.” If Evans is right that “less is sampled”, then the two studies are definitely incompatible. But if look only at Evans’ conclusions about citations, the two studies may be compatible. Evans is saying that access to more literature reduces the number of different sources one cites, and Eger is saying that it increases (“dramatically” increases) the number of articles one requests or samples. Researchers may be viewing more articles but citing fewer. Are they using their enhanced access to browse neighboring topics? Are they exploring serendipitous discoveries, only some of which turn out to be citable? Does their wider reading help them zero in on citable research?

Brandon Keim asked (and commenters are answering):

What do you think, scientist and scholar Wired Science readers, especially those whose careers have spanned the jump from paper to screen? What have you gained — or lost — from the internet’s rise?

Philip Davis:

In other words, it is not the additional online access that this causing the change in citation behavior but the tools that accompany the online access — tools that allow readers to link to related articles, rank by relevance, times cited, etc. It is these tools that signal to the reader what is important and should be read. The result of these signals is to create herding behavior among scientists, or what Evans describes as consensus building.
A highly-efficient publication system can come with unanticipated consequences — the loss of serendipity. In an earlier blog post, we discuss how the Internet is changing reading behavior in general, reducing the depth of inquiry. In another blog, we discuss how signaling can help readers save time.

David Crotty:

Evans brings up a few possibilities to explain his data. First, that the better search capabilities online have led to a streamlining of the research process, that authors of papers are better able to eliminate unrelated material, that searching online rather than browsing print “facilitates avoidance of older and less relevant literature.” The online environment better enables consensus, “If online researchers can more easily find prevailing opinion, they are more likely to follow it, leading to more citations referencing fewer articles.” The danger here, as Evans points out, is that if consensus is so easily reached and so heavily reinforced, “Findings and ideas that do not become consensus quickly will be forgotten quickly.” And that’s worrisome-we need the outliers, the iconoclasts, those willing to challenge dogma. There’s also a great wealth in the past literature that may end up being ignored, forcing researchers to repeat experiments already done, to reinvent the wheel out of ignorance of papers more than a few years old. I know from experience on the book publishing side of things that getting people to read the classic literature of a field is difficult at best. The keenest scientific minds that I know are all well-versed in the histories of their fields, going back well into the 19th century in some fields. But for most of us, it’s hard to find the time to dig that deeply, and reading a review of a review of a review is easier and more efficient in the moment. But it’s less efficient in the big picture, as not knowing what’s already been proposed and examined can mean years of redundant work.

Martin Fenner:

The greater availability of research papers in recent years thanks to electronic publication (and open access) should broaden and not narrow the papers that we read and ultimately cite in our own publications. But looking at my own behavior when reading papers or writing a publication, and thinking about many discussions we had on related topics, these findings make perfect sense.
Today’s technology allows us to make the distribution of scientific papers in electronic form very efficient, and thanks to this technology we have new business models (author-pays) and an ever-increasing number of journals. Access to research articles is now easier, cheaper and for a broader audience than in ever was before. This is of course a wonderful development, but unfortunately creates a new problem: information overflow and how to filter out the relevant information.
Twenty years ago the typical researcher would use the personal or institutional journal subscription to regularly follow the important papers in his field. Index Medicus and Current Contents were used to find additional articles, but they were cumbersome to use. Today few researchers regularly read printed journals. Most papers are found by searches of online databases and by subscriptions of tables of content by email or RSS. There are many clever tools to facilitate this, but most people probably are overwhelmed by the information and stick to some very specific research interests and high-profile journals.

Thomas Lemberger:

In any case, the study highlights two complementary strategies in information retrieval: finding relevant papers by targeted searches versus staying informed on a broad range of topics by systematic browsing. In our Google-driven era, we may have the tendency to forget the importance of good old-fashioned ‘table-of-content-skimming’ to stimulated cross-disciplinary thinking, widen our horizon and cultivate scientific curiosity.
Perhaps it is a specificity of printed media to provide “poor indexing” and therefore enforce broad exposure to unrelated areas of research. On the other hand, some web technologies already help to browse through vast amounts of online publications (for example an RSS aggregator helps me to generate a daily literature survey; this can be further combined, for example here at Frienfeed, with other community-centered feeds; other aggregators highlight information by automatic clustering: Postgenomic and Scintilla). However, these tools remain imperfect and, in our reflection on the future of scientific publishing, we will need to find the right balance between the two strategies above and think of how the increasing efficiency of searching engines can be complemented by means providing continuous exposure to diversity.

Bill Hooker does the most detailed analysis of the paper so far (so click and read the whole thing, graphs and all):

What this suggests to me is that the driving force in Evans’ suggested “narrow[ing of] the range of findings and ideas built upon” is not online access per se but in fact commercial access, with its attendant question of who can afford to read what. Evans’ own data indicate that if the online access in question is free of charge, the apparent narrowing effect is significantly reduced or even reversed. Moreover, the commercially available corpus is and has always been much larger than the freely available body of knowledge (for instance, DOAJ currently lists around 3500 journals, approximately 10-15% of the total number of scholarly journals). This indicates that if all of the online access that went into Evans’ model had been free all along, the anti-narrowing effect of Open Access would be considerably amplified.
In fact, the comparison between print and online access is barely even possible when considering Open Access information. The same considerations of cost — who can afford to read what — apply to commercial print and online publications, but free online information has essentially no print ancestor or equivalent. Few if any scholarly journals were ever free in print, so there’s a huge difference between conversion from commercial print to commercial online on the one hand, and from commercial print to Open Access on the other.
Indeed, I would suggest that if the entire body of scholarly literature were Openly available, so that every researcher could read everything they could find and programmers were free to build search algorithms over a comprehensive database to help the researchers do that finding, then in fact the opposite effect would obtain. Perhaps it’s true that the more commercial online access you have, the less widely a researcher’s literature search net is cast, but as I mentioned above I see no reason to attribute that more to the mode of access than to its cost.

Perhaps with greater accessibility, people have quit citing old papers which they used to cite just because everyone always cites those papers without even reading them. Those who have the least access, tend to cite very old stuff, textbooks, popsci articles, e.g., these guys. Those who have good access can both browse and search and find what is truly relevant to their work. They cite only stuff that they have actually read and found useful. Perhaps people are just getting more honest.

Cool bloggy miscellanea

Scientific Collectivism 1: (Or How I Stopped Worrying and Loved Dissent):

I want to bring up a discussion about what I perceive is a dangerous trend in neuroscience (this may be applicable to other areas of science as well), and that is what I will term “scientific collectivism.” I am going to split this into two separate posts because it is so long. This first post is the weaker arguments, and what I see are the less interesting aspects of scientific collectivism-however, they deserve a discussion.

What will you be? and the related Friday Poll: Tinker, Tailor, Biologist, Researcher. So, how do you call yourself when you are introduced to a stranger?
A little muddled (especially in not making sufficient distinction between peer-reviewed Journals and pop-science magazines), but an interesting look from the outisde in: The High Cost Of Science:

Let’s say, for the sake of argument, that you are interested in science and you want to learn more about it. Maybe you’re tired of creation vs evolution debates and you want to do the research yourself, or maybe you just want to become a more informed citizen. Whatever your reasons, you have a few options but none of them are all that appealing.

Online Alarm Clock which, once set, does not need to be online in order to ring on time. Does it work on an iPhone?
Fair Use Rights:

Intellectual property, copyright, creative commons, copyleft, open access… These are all terms high on the science and other agenda these days. For example, public-funded scientists the world over are calling for research results to be available free to them and their peers for the public good and for the good of scientific advancement itself. Librarians likewise are also interested in the fullest dissemination and sharing of knowledge and information, while user-creators and the new breed of citizen journalists that are the result of the Internet Age are also more liberal in their outlook regarding the proprietary nature of creative works.

Survival of the Abudant: Mutational Networks Constrain Evolution:

What has been found over the last few years is that these neutral mutations occur in networks. That means that there are little fleets of genotypes, all of the same “fitness”, that have overlapping series of neutral mutations. Most of these fleets are small, but a few are larger, and its the larger fleets of genotypes that the researchers in this study focused on. The large networks tend to be adjacent to a pretty large number of phenotypes. So you have all these little neutral mutations, next to RNA with a wide variety of phenotypes. Do these little neutral mutations influence evolution after all?

The Kudlow Year:

We’ve had a terrible year. Obvious problems remain, along with whatever else lurks beneath the waterline. Wall Street showed some optimism about the future yesterday, but we’ve still got a long way to go. A lot of this boils down to arithmetic. Pay more attention to the numbers and less to ideologues on teevee or the web who try to tell you different.

Scribd and Lulu partner:

Print-on-demand publisher Lulu (which offers an OA option for content providers) and document sharing site Scribd are partnering, according to ReadWriteWeb. Lulu will begin making some of their OA content available in Scribd’s iPaper format (a “sort of a YouTube for PDFs”), including utilizing iPaper’s ability to embed AdSense ads within the documents.

Rational Voters?

The underlying assumption, of course, is that issues matter, that voters are fundamentally rational agents who vote for candidates based on a coherent set of principles. In other words, they assume that my political preferences reflect some mixture of ideology and selfish calculation. I’ll vote for the guy who best matches my geopolitics and tax bracket.
The problem, as political scientist Larry Bartels notes, is that people aren’t rational: we’re rationalizers. Our brain prefers a certain candidate or party for a really complicated set of subterranean reasons and then, after the preference has been unconsciously established, we invent rational sounding reasons to justify our preferences. This is why the average voter is such a partisan hack and rarely bothers to revise their political preferences.

I Like My Facts Well Done and Humorless. The funny take on Sizzle.
PhysioProf rants and raves on Feministe for a couple of weeks or so. Check the tribal wars in the comments!
A pierced scientist? AKA, I need a mentor:

It occured to me yesterday that I have a lot of questions to ask and nobody to go to for answers. I really need a mentor of some kind. I mean, I have an academic advisor, but he’s an old white man who doesn’t make any attempt to engage me in conversation. He’s very standoffish and business-oriented whenever I meet with him, which I think has been once a year for the last three years. I doubt he knows my name. And I have Dr. Calhoun, my research advisor, who I’m starting to warm up to a little bit but I’m not really at the point where I can ask him the kinds of personal questions that are the most burning. I doubt I’ll ever be able to not be intimidated by him, especially since I found out he’s the chair of the graduate admissions committee.

Obligatory Reading of the Day: Cameron Neylon on Open Science

Policy for Open Science – reflections on the workshop:

One thing that was very clear to me was that the attendees of the meeting were largely disconnected from the more technical community that reads this and related blogs. We need to get the communication flowing in both directions – there are things the blogosphere knows, that we are far ahead on, and we need to get the information across. There are things we don’t know much about, like the legal frameworks, the high level policy discussions that are going on. We need to understand that context. It strikes me though that if we can combine the strengths of all of these communities and their differing modes of communication then we will be a powerful force for taking forward the open agenda.

How to read a scientific paper

Here is a good example. Step-by-step.

Obligatory Reading of the Day: Opening up Scientific Culture

Why are so many scientists reluctant to make full use of Web 2.0 applications, social networking sites, blogs, wikis, and commenting capabilities on some online journals?
Michael Nielsen wrote a very thoughtful essay exploring this question which I hope you read carefully and post comments.
Michael is really talking about two things – one is pre-publication process, i.e., how to get scientists to find each other and collaborate by using the Web, and the other is the post-publication process, i.e., how to get scientists to make their thoughts and discussions about published works more public.
Those of you who have been reading me for a while know that I am thinking along some very similar lines. If you combine, for instance, my review of Rainbows End by Vernor Vinge with
On my last scientific paper, I was both a stunt-man and the make-up artist with Journal Clubs – think of the future! with The Scientific Paper: past, present and probable future, you will see a similar thread of thinking.
But, what do you think?