Just replace these with Jane Hamsher, Josh Marshall, ….

Obama presser.jpg
Source.

Obama on Science


No comment….(can you imagine Bush saying anything like this? Ever? Any Republican?)

Message to New York City readers

Mrs.Coturnix and I will be in NYCity this week. My main business is the Open Science panel at Columbia on Thursday afternoon, which I hope you can attend.
For a more informal way to meet, let’s gather at Old Town bar near Union Square at 8pm on Friday night. Tell your friends! And I hope to see you soon.

Today’s carnivals

Praxis No. 6 is up on mudphudder
Carnival of the Green #167 is up on Reclaimed Home

My picks from ScienceDaily

Continue reading

Clock Quotes

Sunlight is said to be the best of disinfectants.
– Justice Louis Brandeis

A smorgasbord….

Being quite busy lately, I accumulated a lot of links to stuff I wanted to comment on but never found time. Well, it does not appear I will find time any time soon, so here are the links for you to comment on anyway (just because I link to them does not mean I agree with them – in some cases quite the opposite):
In Defense of Secrecy :

Given the pervasive secrecy of the Bush-Cheney administration, and the sorry consequences of that disposition, President Barack Obama’s early emphasis on openness in government seems almost inevitable. One of the first official communications issued by the new administration, on Jan. 21, ordered government agencies to adopt a presumption in favor of disclosure when responding to Freedom of Information Act (FOIA) requests and called for new FOIA guidelines to replace those promulgated under Bush. A later directive instructed the heads of all government agencies to strive for “transparency and open government.” Ornamenting the first order was a quotation from the great progressive reformer Justice Louis Brandeis: “Sunlight is said to be the best of disinfectants.”

The Future of the News:

After years in trouble, American newspapers are finally up against the wall.
Advertising, vanished. Profits, gone. Losses, mounting very rapidly. Around the country, newsrooms are being hollowed out, papers are shrinking, some are letting go of daily publication. Some are going away.
So, what if? What if your local newspaper just disappeared? In a world of red ink, bankruptcies, layoffs and cutbacks, it’s possible. So, what then?

Farewell to All That: An Oral History of the Bush White House :

The threat of 9/11 ignored. The threat of Iraq hyped and manipulated. Guantanamo and Abu Ghraib. Hurricane Katrina. The shredding of civil liberties. The rise of Iran. Global warming. Economic disaster. How did one two-term presidency go so wrong? A sweeping draft of history–distilled from scores of interviews–offers fresh insight into the roles of George W. Bush, Dick Cheney, and other key players.

At Voice of San Diego, a newsroom flourishes:

With several big-city dailies facing closure and the cover of Time last week pondering the fate of the American newspaper, I listened to young Voice of San Diego journalists talk about their work with words like “exhilarating,” “fulfilling” and “fun.” My tiny, ink-sotted heart soared.
The lessons out of the sunny offices on Point Loma appear to be these: A local news site can flourish on charitable donations. It helps to have one big benefactor to get things started. It makes more sense to cover a few topics well, rather than a lot poorly.

Political Science:

Behind him hangs a copy of Jacques-Louis David’s celebrated portrait of Antoine-Laurent Lavoisier, the French chemist. Varmus is one of our leading scientific figures, a Nobel Prize-winning cancer researcher who advises President Obama, but I’m not sure this is an auspicious image. Lavoi­sier’s own entanglement in politics led to his beheading during the French Revolution. Thankfully, Varmus seems quite adroit in public matters. He has also written a perceptive book about science and its civic value, arriving as the White House renews its acquaintance with empiricism.

Do we need Science Journalists? :

For one, as far as I am concerned most scientists are not particularly good writers (I include myself in that) and since I appreciate a piece of good writing I sincerely hope professional journalism will prevail. Having acquired the necessary skills and appropriate education certainly helps to this matters. I don’t know what Bora’s standards are, but I find the vast majority of science blogs not particularly well written (YOU obviously belong to the minority of brilliant writers).

More discussion here and here.
Survival of the Viral:

Studying genetic “mistakes,” like endogenous retroviruses, would have led us to a theory of evolution, even if Charles Darwin had not.

Why Facebook Is for Old Fogies:

Facebook is five. Maybe you didn’t get it in your news feed, but it was in February 2004 that Harvard student Mark Zuckerberg, along with some classmates, launched the social network that ate the world. Did he realize back then in his dorm that he was witnessing merely the larval stage of his creation? For what began with college students has found its fullest, richest expression with us, the middle-aged. Here are 10 reasons Facebook is for old fogies:

What’s the Matter With Teen Sexting?:

It’s unclear from this exchange what Gladstone believes kids need to be protected from or what issue Balkam is solving. But neither of them came to the logical conclusion of the Harvard study: that we should back off, moderate our fears, and stop thinking of youthful sexual expression as a criminal matter. Still, Balkam wants to call in the cops.
Maybe all that bullying is a mirror of the way adults treat young people minding their own sexual business. Maybe the “issue” is not sex but adults’ response to it: the harm we do trying to protect teenagers from themselves.

Republican Taliban declare jihad on Obama:

The Democrats and the liberal base have responded to all this with a mixture of cynicism and their own partisanship. They rolled their eyes at Obama’s outreach to Republicans; they hated the inclusion of the other party in the cabinet and had to swallow hard not to complain about the postpartisan rhetoric. Their cynicism is well earned. But my bet is that Obama also understands that this is, in the end, the sweet spot for him. He has successfully branded himself by a series of conciliatory gestures as the man eager to reach out. If this is spurned, he can repeat the gesture until the public finds his opponents seriously off-key.

A Balancing Act on the Web :

LAST week, I wrote that a hastily published article on The Times’s Web site highlighted a fear in newsrooms that the Internet, with its emphasis on minute-to-minute competition, is undermining the values of print journalism, which put a premium on accuracy, tone and context.

The ethics of science journalism:

This unique theme section brings together the views of all parties involved in science journalism and bringing science to the public today: writers (freelance and staff), editors, publishers, and scientists themselves. The theme section will be built online.

An Eternal Optimist — But Not A Sap:

Obama is a long way from matching the achievements of Lincoln and Roosevelt, of course. (If Obama, and the country, is lucky, he won’t have to.) But his common inclination to “steer from point to point” may serve him and the country well, especially since Obama has inherited problems of a magnitude faced by few of his predecessors other than those two titans. Obama recognizes the obvious challenge those problems present, but also sees in them opportunity. “I think that there are certain moments in history when big change is possible… certain inflection points,” he said. “And I think that those changes can be for the good or they can be for the ill. And leadership at those moments can help determine which direction that wave of change goes.”

The Oligarchs:

Everyone is always saying: how can we fix the problem as long as the people we have in charge are the people who created the problem in the first place? Very true in many ways. I’ve said it a lot myself. But this point has brought it home to me in a much more concrete way. The assumptions, the vested interests, the wealth, the political power are just too much to overcome.

The No-Stats All-Star :

The virus that infected professional baseball in the 1990s, the use of statistics to find new and better ways to value players and strategies, has found its way into every major sport. Not just basketball and football, but also soccer and cricket and rugby and, for all I know, snooker and darts — each one now supports a subculture of smart people who view it not just as a game to be played but as a problem to be solved. Outcomes that seem, after the fact, all but inevitable — of course LeBron James hit that buzzer beater, of course the Pittsburgh Steelers won the Super Bowl — are instead treated as a set of probabilities, even after the fact. The games are games of odds. Like professional card counters, the modern thinkers want to play the odds as efficiently as they can; but of course to play the odds efficiently they must first know the odds. Hence the new statistics, and the quest to acquire new data, and the intense interest in measuring the impact of every little thing a player does on his team’s chances of winning. In its spirit of inquiry, this subculture inside professional basketball is no different from the subculture inside baseball or football or darts. The difference in basketball is that it happens to be the sport that is most like life.

Legal Guide for Bloggers:

Whether you’re a newly minted blogger or a relative old-timer, you’ve been seeing more and more stories pop up every day about bloggers getting in trouble for what they post.
Like all journalists and publishers, bloggers sometimes publish information that other people don’t want published. You might, for example, publish something that someone considers defamatory, republish an AP news story that’s under copyright, or write a lengthy piece detailing the alleged crimes of a candidate for public office.
The difference between you and the reporter at your local newspaper is that in many cases, you may not have the benefit of training or resources to help you determine whether what you’re doing is legal. And on top of that, sometimes knowing the law doesn’t help – in many cases it was written for traditional journalists, and the courts haven’t yet decided how it applies to bloggers.

Nouriel Roubini: Only Way To Save US Banking System Is To Nationalize It:

The U.S. banking system is close to being insolvent, and unless we want to become like Japan in the 1990s — or the United States in the 1930s — the only way to save it is to nationalize it.
As free-market economists teaching at a business school in the heart of the world’s financial capital, we feel downright blasphemous proposing an all-out government takeover of the banking system. But the U.S. financial system has reached such a dangerous tipping point that little choice remains. And while Treasury Secretary Timothy Geithner’s recent plan to save it has many of the right elements, it’s basically too late.

The Internet, New Media, Old Media and Fame:

What is fame? When you use the word the majority of people would start rhyming of names like Angeline Jolie, Rock Hudson, JFK and even now with Barak Obama. Fame is often thought of as being the thing that actors, musicians, politicians and in very rare cases regular people can achieve through their actions. Old Media thrives on famous people because of their ability to get people to fork over their money time and time again. This type of fame though is what I would refer to as global fame. It is a fame that can cross generations and oceans but it isn’t the only kind of fame there is.

WooHoo! Blogging is dead:

Of course this is all because Dan Lyons pontificated in Newsweek – which he also pointed to from his blog – that that there is no money to be made with blogging. Of course his idea of making money is something that probably has to surpass his salary from Newsweek who I am sure gave him the big high five over the post.
I won’t bother re-hashing all the different ways that Lyons probably profited quite well from his short stint as a blogger. After all how many times can you say book deal, better paying job with more name recognition or even all the speaking dates before you get the idea that Mr. Lyons is pretty well full of shit. Sure he used the lousiest ad network out there and really only clued into the fact that there were better ones months before he supposedly shut down the Fake Steve Jobs blogs out of respect of the Real Steve Jobs health.

5 Things We Learned About Teens at TOC:

They hung out with real teenagers in their homes to get a look at their creative processes. When choosing which teens to follow, they looked for those who were creative, but not necessarily planning to go into art or design after high school. They picked those who were involved in interesting self-expression activities and who were creating digital media to share with others outside their immediate circles of friends. Here are five not-so-obvious takeaways (beyond the fairly apparent “Teens want to create identities for themselves online” and “In general, teens are pretty tech-savvy”). (The panel didn’t focus much on book publishing, but it provides useful background to YA publishers who want a better look at what their target audiences are doing online.)

Andrew Wakefield, autism, vaccines and science journals:

A word about peer review. This is the process whereby journal editors send manuscripts to experts in the field for their evaluation of scientific soundness. Based on the comments, editors then make a decision as to whether to publish or not. That decision may or may not be the same as the reviewers’. There are many considerations whether to publish something or not (is it of sufficient interest to the readership or does it make enough of a contribution to the field, for example). In general, however, depend on reviewers for the science. Most journals do closed, anonymous reviews. This means that the authors don’t know who the reviewers are and the reviews are not provided to the readers. Often the names of the authors are also kept from the reviewers so as not to prejudice their judgment. Some journals (like the one I edit) practice open review, meaning that reviewers’ names are known to the authors (and vice versa) and that the reviews themselves are available to readers when the paper is published. In the case of the Wakefield paper we don’t know the names of the reviewers or what they said.

A guide to the 100 best blogs – part I:

The online world of the bloggers and how you can connect, communicate, publish your thoughts or diaries and ‘spy’ on the famous

Who-o-o are you? Who who? Who who?:

There’s been quite a lot of discussions going on lately about author identification: Raf Aerts’ correspondence piece in Nature (doi:10.1038/453979b), discussions on FriendFeed, … The issue is that it can be hard to identify who the actual author of a paper is if their name is very common. If your name is Gudmundur Thorisson (“hi, mummi”) you’re in luck. But if you are a Li Y, Zhang L or even an Aerts J it’s a bit harder. Searching PubMed for “Aerts J” returns 299 papers. I surely don’t remember writing that many. I wish… So if a future employer would search pubmed for my name they will not get a list of my papers, but a list of papers by authors that have my name. Also, some of my papers mention jan.aerts@bbsrc.ac.uk as the contact email. Well: you’re out of luck, I’m afraid. That email address doesn’t exist anymore because I changed jobs.

How I made over $2 million with this blog:

If I had any advice to offer it’s this — get in the habit of communicating directly with the people you want to influence. Don’t charge them to read it and don’t let others interfere with your communication. Talk through your blog as you would talk face to face. You’d never stop mid-sentence and say “But first a word from my sponsor!” — so don’t do that on your blog either. I can’t promise you’ll make any money from your blog, and I think the more you try the less chance you have. Make a good product and listen to your customers to make it better, and use the tools to communicate, and you may well make money from the whole thing. To expect the blog alone to pay your bills is to misunderstand what a blog can do. You’ll only be disappointed like Dan Lyons was.

Separating science and state:

Government should have no role in funding scientific research. I say this as a person who not only greatly admires scientific research and its accomplishments, but as a person who believes strongly in the scientific enterprise in general–by which I mean, someone who believes that reason is the only proper means of knowledge and who has no truck with religion and tradition and authoritarianism. Just to get my bona fides out of the way, I am seriously devoted to and interested in all forms of science, particularly biology, and have written at great length in defense of science and the material and intellectual–indeed, spiritual–progress it has brought us. Of all the kinds of corporate welfare, I am least opposed to science welfare.

Why it’s good for us to fund scientific research.:

Tim Sandefur and I don’t agree about the proper role of government when it comes to funding scientific research. He fairly strongly believes that there are many reasons why it’s wrong for the government to fund scientific research. Tim’s provided a number of reasons to support his belief, and I agreed to use my blog as a platform to make my own case for the involvement of government in science.
In the abstract, many of the reasons that the government should not be involved in funding research sound fairly compelling. Unfortunately, those arguments were made on the internet. At the end of the day, the medium undercut the message.

A rebuttal to Mike Dunford:

Mike Dunford starts out his rebuttal cleverly pointing to the Internet as an example of the way government-subsidized research can help promote the American standard of living. Of course, it’s true that some of the research projects government has funded have ended up producing some pretty cool things. But it doesn’t undercut the message: in fact, this example makes two important points that support my position.

The Tangled Bank: An Introduction to Evolution:

This week of all things Darwin seemed like a good time to share some news about a project I’ve been working on for the past few months. It’s a book called The Tangled Bank: An Introduction to Evolution.
The inspiration for the book came from a conversation I had last year with the folks at Roberts & Company, a publishing company. They had noticed a growing number of classes about evolution for non-biology-majors, and asked if I’d be interested in writing a textbook for them. I was excited by the prospect of being able to bring together the things I’ve learned and written about over the past few years, as evolutionary biologists have made a string of surprising new advances in understanding the history of life (many of which I’ve written about here at the Loom).

ISI Draws Fire from Citation Researchers, Librarians:

A new document classification is creating confusion and drawing fire from the bibliometrics community. Confusion over the new “proceedings paper” designation in ISI’s Web of Science has many questioning whether the new classification will alter journal impact factors.

The Ideology of the Media:

It’s also that establishment journalists get disoriented by any story that doesn’t fit into their pre-formed cookie cutter narratives. They spend all their adult lives inside the bubble and just can’t relate in a real way to the rest of the country – as you’ve written about… Maybe a few of them can perceive the realness of public anger that is the fuel for social movement politics, and maybe those few can perceive the actual threat to the Establishment.

198 Scientific Twitter Friends:

Follow me on twitterI’ve been on Twitter since June 2007 and have met a lot of interesting, helpful, and generally nice people on there. Many of my almost 1400 friends and followers on twitter are connected with science in some way, they’re scientific tweeps in other words, or to coin a phrase, scientwists.
Originally, I listed 100 science types, but then more friends and followers asked if they could be on this list, so now we have almost 200. If you’re a scientwist and want to join them then tweet me, comment here, follow me, or retweet
this link bit.ly scientwists be sure to let me know and I’ll add your link and bio.

Paper Chase: A Q&A with Randy Siegel (search blogs, twitter and friendfeed for this article, to see why it is very wrong):

Absolutely. It’s the infrastructure, it’s the professional training, it’s the ability to condense massive amounts of information into accessible prose for the reader and the online visitor. It’s the editing. I mean, this notion that you don’t need editors anymore is laughable. Editors make things accessible for readers and online users, and they help educate all of us about stories and issues that we otherwise might not see. I highly doubt that your favorite blogger, for example, is in a position to fly to Iraq and cover what’s going on there, or to fly to the far East and decipher our relationship with China as an economic superpower, or to go into City Hall and expose instances of municipal graft and corruption, or to get behind the scenes of a major sporting event and help people understand why a game turned out the way it did. I believe that, in journalism, you get what you pay for. And quality journalists will always have a role in our society. And as newspaper companies evolve, great journalism will now be more important than ever. Across multiple platforms.

Battle Plans for Newspapers:

Virtually every newspaper in America has gone through waves of staff layoffs and budget cuts as advertisers and subscribers have marched out the door, driven by the move to the Web and, more recently, the economic crisis.
In some cities, midsized metropolitan papers may not survive to year’s end. The owners of the Rocky Mountain News and The Seattle Post-Intelligencer have warned that those papers could shut down if they can’t find buyers soon. The Star Tribune of Minneapolis recently filed for bankruptcy. The Detroit Free Press and The Detroit News will soon stop home delivery four days of the week to cut operating costs. Gannett, which owns 85 daily newspapers in this country, recently said it would require most of its 31,000 employees to take a week of unpaid leave.
What survival strategies should these dailies adopt? If some papers don’t survive, how will readers get news about the local school board or county executive?

non-anonymous peer review:

I spent this afternoon acting as a voluntarily non-anonymous peer reviewer – its scary. I ended up advocating rejection of the article I was reading and I have to say that Vince Smith(see end of linked post) was absolutely right that the act of signing your review “keeps you in check”. Knowing from the outset that your words are going to be linked to your name can really change what you have to say – it certainly makes you think about it for a while longer. It is scary though – I hope that I managed to convey enough of my reasoning and suggestions for ways to improve the article that the authors don’t despise me and attempt to ruin my life… I also hope that the editors of the journal manage to acquire at least one additional reviewer for this manuscript – safety in numbers! Or perhaps the editors will strip my name from my comments? Time will tell I guess.

SnailMailTweet:

mail us a tweet, we’ll post it on Twitter

Why the New York Times and Harvard Should Merge (someone wrote a good rebuttal of this, but now I can’t find who and where? – Oh, found it: PhysioProf):

But both of these are really points on a continuum. Journalists have found that in addition to breaking stories, they need to do analysis. Academicians have discovered that in addition to reviewing the past, they need to pay attention to the the future.

11 Ways Print Journalism Can Reinvent Itself:

Print journalism is in a tailspin. Embracing the Web is the obvious solution, but how is that best done? Lex Alexander, who spearheaded a well-regarded new media effort at the Greensboro, NC, News & Record, offers these tips. Notice that a few start with the word “invest,” which is counter to much recent industry wisdom.

Obama Aides Rip Cable News, D.C. Media And Political Elite:

Here’s an interesting dynamic: The yawning gap between what the pundits say about who’s winning the stimulus war and what the polls say the public thinks has created an opening for the Obama team to reclaim Obama’s campaign outsider mantle, which had slipped away during the transition to governing.

If you don’t have a blog you don’t have a resume (Part 1):

The point here is to make the case that blogging is good for your career. It’s been good for me and it’s been good for a lot of other people and I think it has potential for everyone.
Now, is everyone a blogger-in-waiting? Of course not. Would absolutely everyone actually benefit from blogging? Probably not. And if absolutely everyone did take up blogging, would the massive amount of noise generated actually cancel itself out and end up hardly benefiting anyone at all? Probably.
That being said, let’s take a look at what’s been making me think about blogging lately.

If you don’t have a blog you don’t have a resume (Part 2):

I’d also like to be more explicit about chicken/egg of interplay between our passion and commitment to the profession that blogging brings out and how that directly feeds into concrete reputation-building and the benefits that may result. In general, I believe that if you blog to become famous (in other words, to explicitly build your reputation, with cynicism not passion), that will be your reputation. If you blog to share and grow and explore, it’s that passion that will hopefully influence your reputation-building efforts and that any concrete benefits that you accrue will reflect that.
Blogging isn’t for everyone. Blog because it’s what you want to do, not because you feel you have to.
That being said, I really I really like how bluntly Neville Hobson puts it: Your Blog is Your CV.

Yet more on uneasy symbiosis of mainstream and citizen journalism:

Rosen’s much stronger and emphatic point, meanwhile, is that the blogosphere v MSM argument isn’t getting us anywhere, so, follks, quit beating this question by attacking “the other.” I could not agree more. The point is not which is better or deserves to die or has great or lousy ethics or good or awful writers. It’s that they bring different strengths and weaknesses and possibilites and constraints, we’ll make the best of both realms if we try to cross-fertilize strengths while avoiding or improving upon weaknesses.

Best of January

I know, I know, it’s middle of February, but I was busy and neglected my duties. So, to catch up with the monthly feature, here is the best of January at A Blog Around The Clock:
Of course, the entire month was dominated by ScienceOnline’09, so the rest of posts were mostly quick links, cartoons and YouTube videos, which is, I hope, understandable. But I did write, post facto, some of my own coverage of the conference, e.g., ScienceOnline09 – Thursday, ScienceOnline’09 – Friday Morning Coffee Cupping, ScienceOnline’09 – Friday Lab Tour: the NC Museum of Natural Sciences, ScienceOnline’09 – WiSE Lacks Shanties, ScienceOnline’09 – Saturday 9am, ScienceOnline’09 – Saturday 10:15am, ScienceOnline’09 – Saturday 11:30am, ScienceOnline’09 – Saturday 2pm, and on the organization of an Unconference, ScienceOnline’09 – Saturday 3:15pm – Blog carnivals and Thank them – they made ScienceOnline’09 possible. And then, there was a very nice article about ScienceOnline09 in BioTechniques.
We revealed the winners – the posts that will appear in The Open Laboratory 2008 and teased you with the cover.
Christina Pikas showed some research on science blogging communities in The Structure of Scientific Blogolutions!
Overlords asked, so we answered: What is science’s rightful place?
Then I had fun with a bad science journalist in Graham Lawton Was Wrong.
And, in a post that comes closest to “science blogging” as narrowly defined, I showed some X-ray images of my dog.

The Giants’ Shoulders # 8 is up!

You can find it on Greg Laden’s blog. Lots of great history of science blogging for the long weekend.

My picks from ScienceDaily

Continue reading

Clock Quotes

Life is action and passion; therefore, it is required of a man that he should share the passion and action of the time, at peril of being judged not to have lived.
– Oliver Wendell Holmes

Carl Zimmer on Darwin (video)

Just a reminder that…

…the next edition of Praxis will be up on Mudphudder on February 15th 2009. This edition will be a thematic one – “I wish that I knew what I know now”.
…the next edition of The Giant’s Shoulders will be up on Greg Laden’s blog, also on February 15th 2009.
…the first inaugural edition of Diversity in Science will be up on Urban Science Adventures! on February 24th, 2009, but the deadline is the 20th.

The six secrets of squid sex

w00t! Miriam Goldstein had a piece published in Slate! The real references to that piece arehere.

A Fable about Trolls

Nanny Goat Gruff and the Internet Trolls:

Once upon a time, there was a nanny goat who lived to wander from field to field, tasting the grass and bushes as she went. It was a simple life: wander, taste, chew, wander again. Sunshine and air and a million flavors were her world. The only problem was that the most complex, interesting flavors were to be found in isolated meadows, only accessible by bridge. And where there were bridges, there were trolls……

Innovation in education

A sixth of a GCSE in 60 minutes?:

Later this year, pupils from Monkseaton high school will file into their new lozenge-shaped school and take their seats before a giant video wall in a multipurpose hall. Here, they will receive a unique lesson: an intense PowerPoint presentation, repeated three times, and interspersed with 10-minute breaks of juggling or spinning plates. After one hour of this study, the pupils will be primed for one sixth of a GCSE. In theory, following this “spaced learning” method, a teenager could sit a GCSE after just three days’ work.
It is a vision of the future that may horrify many parents, teachers and the educational establishment. It challenges how we teach our children and casts doubt on GCSEs and, perhaps, the validity of our entire school system. But teachers and thinkers from around the world are making a pilgrimage to Monkseaton to investigate spaced learning, which has been devised and tested in this tatty state comprehensive over the last four years.
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A series of careful trials yielded fascinating results: 48 year 9 pupils who had not covered any part of the GCSE science syllabus were given a complete biology module in a 90-minute spaced learning lesson. A week later, they took the relevant GCSE multiple-choice exam (a year earlier than normal). Twelve months on, the same set of pupils took another GCSE science paper after a conventional four months of study. While average scores for the second paper were higher (68% versus 58%), more than a quarter of the pupils scored higher after spaced learning than through conventional study. Despite studying for just 90 minutes with spaced learning, 80% of the class of 13- and 14-year-olds got at least a D grade.
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Monkseaton’s futuristic new school opens in September. It will be where Kelley hopes to expand spaced learning, in classrooms that won’t be square (“We don’t have to have schools built in squares,” he says) and will feature special intensive lighting to boost teenagers’ concentration and wakefulness. Kelley has studied research on teenagers’ circadian rhythms that shows they get going later in the day than adults – hence those epic teenage lie-ins – and hopes to start lessons at the more teen-friendly hour of 10.30am.
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I’m inclined to believe that there must be more to making memories stick than findings derived from dissecting a rat’s hippocampus. Scientists would probably say that is because – despite my GCSE refresher – I don’t fully understand the complex advances in neuroscience. Whatever the truth of it, something special is happening at Monkseaton. And if other teachers and academics open their minds to it, this may be just the beginning of a revolution in our classrooms.

Do you have a problem?

If so, don’t worry. GOP has a solution for all your problems. Just describe your problem to the GOPProblemSolver and you will get the straight answer how to solve it:
GOPProblemsolver.JPG

Darwin Day recap

On Thursday, for Darwin’s 200th birthday, I went down to Raleigh to the Museum of Natural Science to hear Carl Zimmer’s talk. The room was packed – I got the last empty seat and there were people standing in the back. A very mixed audience, as Museum talks usually are – there were evolutionary biologists there from Nescent and the W.M.Keck Center for Behavioral Biology at NCSU, there were Museum staff, and then there were interested lay-people, museum-goers, with no formal background in science but interested and curious. It is not easy giving a talk to such a mixed audience – how to keep the jaded Evolution-warriors interested, while not going over the heads of the non-experts, but Carl delivered masterfully.
After introducing briefly Darwin the person and his work, in broad brush-strokes, Carl did an interesting thing – he chose several stories and told us what Darwin thought and wrote about them, and what we now know due to recent exciting research: from evolution of whales, through human evolution, to bacteria and viruses. The result was that he did not tell but demonstrated two points: first, that Darwin was generally correct, and second, that evolutionary biology made tremendous strides over the past 150 years. With each story one was left to think – how cool Darwin would think the new findings are if he were suddenly resurrected and shown the data!
The questions afterwards were good – not high-tech questions one would hear at a scientific conference, but good, thoughtful questions by lay audience, the kind often heard at Science Cafes. And only one question refered to the Culture Wars – how do we deal with the existence and influence of Creationists in the USA? If there were any Creationists in the audience, they certainly remained quiet and inconspicuous.
Afterwards, Carl and I went back to Durham and joined a bunch of local bloggers, scientists and science communicators, Craig McClain, Anton Zuiker and Russ Campbell among others, for some food and beer at Tyler’s. Good time was had by all.
Finally, you should also check Carl’s latest article in TIME: Evolving Darwin

History of Mammoth discoveries in Asia

John McKay has been blogging his research on the early days of mammoth discoveries in Asia and it is an amazing read! Who ever said that academic writing has to be dull!?
Fragments of my research – I:

Studying early knowledge of mammoths presents two problems. The first, is that the people who found mammoth remains were almost never literate and the people who wrote about mammoth remains were so far removed that they almost always got their information second or third hand or worse. The second problem is that, lacking a common name for mammoth remains, it is a huge task to sort out references to mammoth ivory from similar materials used in carving. Giles Fletcher’s fish tooth ivory is most likely walrus ivory. Notice how close his description is to Kashghari’s and Kirakos’. Does that mean they were all describing walrus ivory? Could they have each been describing something different? And, while Fletcher’s description is clearly of a walrus, can we be sure that all of the ivory he saw came from the same source? Was he throwing mammoth ivory in with walrus ivory and calling them the same thing? More research is in order.

Fragments of my research – II:

At this point, an interesting fact to notice is that none of the Chinese sources have mentioned ivory yet. This doesn’t necessarily mean that the various shu are not mammoths. Although European naturalists had enthusiastically studied the mammoth since about 1700, it wasn’t until the twentieth century that they knew how the tusks were positioned. The reason for this was that they had never recovered a skull with the tusks still attached. Though generous bounties were offered for mammoth remains, the Siberian natives never reported them until after they had removed and sold the tusks. It’s possible that a similar process was at work in rural China.

Fragments of my research – III:

The generation of men who conquered Siberia were mostly illiterate and, even if they could write, they had little time for natural history, anthropology, or anything else not related to surviving, extracting wealth, and making it back alive. By the middle of the next century, a different type of person began to arrive in Siberia. Along with a more settled population came educated administrators, diplomats, and higher church authorities who had time to more closely look at the land and its treasures. At some point, they became interested in the giant bones and ivory that the natives called “mammoth.”

Fragments of my research – IV:

For centuries, if not millennia, before 1600, carvable materials had been coming out of northern Eurasia along with descriptions of large buried monsters. Of the surviving written descriptions, it’s clear that many of them refer to fossil mammoth ivory and frozen mammoth carcasses, but, with many of the descriptions, it’s less clear what the writers referred to. For historians and biologists, one of the biggest problems in sorting these descriptions out is, that the ancient writers used a large number of different terms and, lacking a common terminology, it’s almost impossible to determine what they were referring to. In the 1690s, the word “mammoth” came out of Siberia and was adopted by the intellectual community of Western Europe. While this improved matters considerably, it also created some ambiguities of its own.

Fragments of my research – V:

Witsen’s narrative of his journey, with the explanation of mammoths, was only a small part of his total work. Besides being buried inside a mountain of other material, the dissemination of Witsen’s information on mammoths was handicapped by the book’s publication history. Witsen never finished with the project. For the rest of his life, he continued to add new material. Only a few copies of each edition were printed, probably for his circle of friends. Only ten copies of his map are known to exist. Nevertheless, the Republic of Letters was a small enough community that word of his new word spread throughout Europe.

Fragments of my research – VI:

Several things stand out in Avril’s account. His translation of mammoth (or mamout or mamant) as Behemot is something that many later travelers will also do. The mention that Persians and Turks use Behemot ivory for knife handles ties into the earlier Arab sources who wrote about the substance khutu, imported from the North and used knife handles. His description of Behemot as a living animal on the shores of the Arctic ocean, suggests that he was applying the word to something other than fossil mammoth ivory. However, the mouth of the Lena River is one of the richest grounds in Siberia for collecting mammoth ivory, which suggests he was. We’ll examine all of these points after we hear from the rest of the Russian travelers.

More still to come, so stay tuned….read Archy.

Today’s carnivals

Linneaus Legacy #16 is up on Seeds Aside
Skeptics’ Circle #105: The Shakespeare Edition, is up on It’s the Thought that Counts
Friday Ark #230 is up on Modulator

Why would anyone still take Republicans seriously at this day and age?

Republicans: Spare Me Your Newfound ‘Fiscal Responsibility’:
recession-republicans.gif

At his press conference on Monday, President Barack Obama had to remind Mara Liasson of Fox News and NPR that it was the Republicans who doubled the national debt over the past eight years and it’s a little strange to be hearing lectures from them now about how to be fiscally responsible. That interchange was my favorite part of the press conference. A savvy inside-the-Beltway reporter of Ms. Liasson’s caliber shouldn’t have to be reminded that George W. Bush and the Republican Congress were among the most fiscally reckless politicians in U.S. history.
—–snip———-
The posturing of the Washington Republicans since Obama was elected proves correct the French philosopher Jean Baudrillard when he outlined his understanding of “simulacrum” in advanced capitalist societies where ideologies and images are copies of copies without originals. It’s the kind of Reaganism mass produced on T-shirts and coffee mugs, not the real record of Reagan’s actions when he was president like his “cutting and running” in Lebanon, or his raising taxes 13 times to ward off an even worse fiscal crisis, or his negotiating in an atmosphere of detente with the Soviet Union he once called an “evil empire.” The Republicans today are conforming to an ideology based on a myth that other Republicans created in 1997, a copy of a copy without an original.
So in 2009 what is left of the Grand Old Party? It appears that Republican politics today have become the politics of pastiche: They love independent women like Sarah Palin and Ann Coulter yet they hate independent women like Hillary Clinton and Nancy Pelosi; they love tax cuts and deregulation yet they also love to control women’s bodies and decide who shall marry and who shall not; they love fictive workers like Joe the Plumber yet they hate real workers who want to pass the Employee Free Choice Act; and they hate the Senate filibuster until they love it to death. And while the “angry white male” is becoming the UNEMPLOYED “angry white male” the Republican National Committee Chair Michael Steele says “work” does not mean “jobs.”

Related

Google Devalues Everything? Bwahahaha!

From TechDirt:

This is wrong on so many levels it’s hard to know where to begin. Google doesn’t devalue things it touches. It increases their value by making them easier to find and access. Google increases your audience as a content creator, which is the most important asset you have. It takes a special kind of cluelessness to claim that something that increases your biggest asset “devalues” your business. Thomson’s mistake seems to be that he’s confusing “price” and “value” which is a bit scary for the managing editor of a business publication. Yes, the widespread availability of news may push down the price (that’s just supply and demand), but it doesn’t decrease the value at all. It opens up more opportunities to capture that value.

Reinventing the News – Reflections on innovation, by Lex Alexander

Greensboro News & Record was one of the first and most innovative newspapers when it comes to the use of the Web, blogs, etc. Now Les Alexander takes a look at the experiment:

I’d love to say we made it all happen. We didn’t. We did, however, learn some lessons. A lot of what we learned is specific to newspaper Web sites, but some of it could be valuable to people in other lines of work, particularly with respect to major projects that involve interacting with customers.

Essentialism beyond just animals

How religion generates social conservatism:

You could make a reasonable case that pencils have a purpose, but pencil shavings just exist. But what about elephants? Religious people and children are, of course, more likely than non-religious adults to say that animals exist for a purpose. But what about men and women? Black people and whites? Rich and poor? Arab and Jew? Do these exist for a purpose? And is it possible for one to become another? Gil Diesdendruck and Lital Haber of Bar-Ilan University in Israel decided to find out what children think.

Bobo’s Paradise Lost

I was listening to NPR in the car yesterday when David Brooks came on and started blathering in his usual vein, revealing with every word his love for the establishment in Washington and his disdain for the proles, and pushing Broderism with all his might. So I was very pleased to see Glenn Greenwald dissect him in great detail in his latest post – David Brooks reveals the mentality of the Beltway journalist:

Here we see the full expression of one of the most predominant attributes of the contemporary Beltway journalist: because they are integral members of the Washington establishment, rather than watchdogs over it, they are incapable of finding fault with political power and they thus reflexively defend it and want it to remain unchanged.
———————————
It’s amazing how explicitly Brooks here is endorsing — and demanding — deliberate deceit of the public. There is, for obvious reasons, extreme anger among the American citizenry towards the piggish sleaze, systematic corruption, and wholesale destruction permeating the political establishment and our political and financial elites. In order to pacify those sentiments, political elites tolerated, perhaps even desired, a presidential candidate with credible outsider pretenses who claimed to empathize with that popular anger and who wanted to combat the political elites who were the targets of it — but only on the condition that he didn’t really mean any of it, that it was all just a means to deceive people into believing that they still live in some sort of responsive democracy and they retain even a minimal ability to shape what the Government does. The anti-Washington rhetoric Obama was spouting was tolerated by media elites only to the extent that none of it was sincere.
————————
What makes this journalistic servitude to the Washington establishment most repellent is that these same pundits generally — and David Brooks in particular — endlessly hold themselves out as the Spokespeople of the Ordinary American, even as they work tirelessly to protect the Washington political class from their beliefs, interests and sentiments. That’s how people like David Brooks pile media deceit (“we speak for ordinary Americans”) on top of political deceit (we view campaign commitments as “blather” to keep the masses satiated and quiet).
The most significant fact of American political life is that political journalists (of all people) see their role primarily as defenders of, servants to, spokespeople for the Washington establishment. That’s how they obtain all of their rewards and remain relevant. The concept of journalists as watchdogs over political power has been turned completely on its head by power-revering servants like David Brooks, who is anything but atypical (indeed, there’s a whole new generation of Beltway journalists who have learned and are eagerly replicating this model). Brooks is about as typical and illustrative as it gets. They benefit substantially from the prevailing rules of political power and, thus, their only concern is to preserve and strengthen it and protect it from the growing dissatisfaction and anger of the peasant class. The more they do that, the more they are rewarded.

Read the whole thing, the links within, and the comments….
Related….

The Carrboro Citizen wins six NC press awards

Well deserved:

The Carrboro Citizen won six awards including two first-place awards in the 2008 North Carolina Press Association’s News, Editorial and Photojournalism contest. The awards were presented Thursday evening at the press association’s banquet in Cary.

Also check their blog. And, they are also now on Twitter.

My picks from ScienceDaily

High-tech Tests Allow Anthropologists To Track Ancient Hominids Across The Landscape:

Dazzling new scientific techniques are allowing archaeologists to track the movements and menus of extinct hominids through the seasons and years as they ate their way across the African landscape, helping to illuminate the evolution of human diets.

Neural Mapping Paints Haphazard Picture Of Odor Receptors:

Despite the striking aromatic differences between coffee, peppermint, and pine, a new mapping of the nose’s neural circuitry suggests a haphazard patchwork where the receptors for such disparate scents are as likely as not to be neighbors.

Mass Media Often Failing In Its Coverage Of Global Warming, Says Climate Researcher:

“Business managers of media organizations, you are screwing up your responsibility by firing science and environment reporters who are frankly the only ones competent to do this,” said climate researcher and policy analyst Stephen Schneider, in assessing the current state of media coverage of global warming and related issues.

Clock Quotes

The smile that flickers on baby’s lips when he sleeps; does anybody know where it was born? Yes, there is a rumor that a young pale beam of a crescent moon touched the edge of a vanishing autumn cloud, and there the smile was first born.
– Rabindranath Tagore

New and Exciting in PLoS this week

This was a busy week for me (hence light posting) so I was amiss somewhat with pointing out cool new PLoS articles. So, let’s see what’s new in PLoS Genetics, PLoS Medicine, PLoS Computational Biology, PLoS Biology, PLoS Pathogens, PLoS Neglected Tropical Diseases and PLoS ONE this week. As always, you should rate the articles, post notes and comments and send trackbacks when you blog about the papers. Here are my own picks for the week – you go and look for your own favourites:
A Basal Sauropodomorph (Dinosauria: Saurischia) from the Ischigualasto Formation (Triassic, Carnian) and the Early Evolution of Sauropodomorpha:

The earliest dinosaurs are from the early Late Triassic (Carnian) of South America. By the Carnian the main clades Saurischia and Ornithischia were already established, and the presence of the most primitive known sauropodomorph Saturnalia suggests also that Saurischia had already diverged into Theropoda and Sauropodomorpha. Knowledge of Carnian sauropodomorphs has been restricted to this single species. We describe a new small sauropodomorph dinosaur from the Ischigualsto Formation (Carnian) in northwest Argentina, Panphagia protos gen. et sp. nov., on the basis of a partial skeleton. The genus and species are characterized by an anteroposteriorly elongated fossa on the base of the anteroventral process of the nasal; wide lateral flange on the quadrate with a large foramen; deep groove on the lateral surface of the lower jaw surrounded by prominent dorsal and ventral ridges; bifurcated posteroventral process of the dentary; long retroarticular process transversally wider than the articular area for the quadrate; oval scars on the lateral surface of the posterior border of the centra of cervical vertebrae; distinct prominences on the neural arc of the anterior cervical vertebra; distal end of the scapular blade nearly three times wider than the neck; scapular blade with an expanded posterodistal corner; and medial lamina of brevis fossa twice as wide as the iliac spine. We regard Panphagia as the most basal sauropodomorph, which shares the following apomorphies with Saturnalia and more derived sauropodomorphs: basally constricted crowns; lanceolate crowns; teeth of the anterior quarter of the dentary higher than the others; and short posterolateral flange of distal tibia. The presence of Panphagia at the base of the early Carnian Ischigualasto Formation suggests an earlier origin of Sauropodomorpha during the Middle Triassic.

Sensory Integration Regulating Male Courtship Behavior in Drosophila:

The courtship behavior of Drosophila melanogaster serves as an excellent model system to study how complex innate behaviors are controlled by the nervous system. To understand how the underlying neural network controls this behavior, it is not sufficient to unravel its architecture, but also crucial to decipher its logic. By systematic analysis of how variations in sensory inputs alter the courtship behavior of a naïve male in the single-choice courtship paradigm, we derive a model describing the logic of the network that integrates the various sensory stimuli and elicits this complex innate behavior. This approach and the model derived from it distinguish (i) between initiation and maintenance of courtship, (ii) between courtship in daylight and in the dark, where the male uses a scanning strategy to retrieve the decamping female, and (iii) between courtship towards receptive virgin females and mature males. The last distinction demonstrates that sexual orientation of the courting male, in the absence of discriminatory visual cues, depends on the integration of gustatory and behavioral feedback inputs, but not on olfactory signals from the courted animal. The model will complement studies on the connectivity and intrinsic properties of the neurons forming the circuitry that regulates male courtship behavior.

Invasive Snails and an Emerging Infectious Disease: Results from the First National Survey on Angiostrongylus cantonensis in China:

Eosinophilic meningitis is caused by the rat lungworm (Angiostrongylus cantonensis). This parasite is endemic in Southeast Asia, Australia, the Caribbean, and on Pacific Islands. Moreover, the disease is emerging in mainland China, which might be related to the spread of two invasive snail species (Achatina fulica and Pomacea canaliculata). Thus far, the biggest angiostrongyliasis outbreak in China occurred in 2006 in Beijing, involving 160 patients. However, detailed information about the national distribution of A. cantonensis and its intermediate hosts is still lacking, and the importance of the two invasive snail species for disease transmission is not well understood. Therefore, a national survey on the distribution of A. cantonensis and its intermediate hosts in China was carried out in 2006/2007. It was found that A. fulica and P. canaliculata were implicated in most angiostrongyliasis outbreaks, and that the distribution of A. cantonensis closely matched that of these snails. The two invasive snail species facilitated the expansion of the parasite, thus probably leading to the emergence of angiostrongyliasis, a previously rare disease, in mainland China.

An Ancient Gene Network Is Co-opted for Teeth on Old and New Jaws:

During evolution, teeth originated deep in the pharynx of ancient and extinct jawless fishes. Later, with the evolution of bony fish, teeth appeared in the mouth, as in most current vertebrates, although some living fishes retain teeth in the posterior pharynx. We integrate comparative morphology, paleontology, and molecular biology to infer the genetic control of the first dentition. We identify Hox genes as important components of an ancient dental gene-regulatory circuit and pinpoint subsequent modifications to this gene network that accompanied the evolution of toothed oral jaws. Furthermore, we highlight a set of genes conserved in the construction of all teeth, regardless of location and lineage. This core dental gene network is evolutionarily essential: nature appears never to have made a dentition without it.

Malaria Control with Transgenic Mosquitoes:

Malaria has been eliminated from a large part of the world. By the mid-twentieth century both North America and Europe were free of the disease, although both had suffered greatly during the prior century [1,2]. While a variety of means were used to achieve this eradication, the most important are thought to be reducing the number of breeding sites for malaria vectors and improving residential areas to separate humans from mosquitoes. Other parts of the world have not been so fortunate. In sub-Saharan Africa, it is now estimated that there are more than 360 million clinical cases and one million deaths due to malaria each year [3,4]. Furthermore, despite ambitious goals such as those of the Roll Back Malaria Initiative to halve malaria deaths by 2010, mortality from the disease has actually risen halfway through the program [5]. Clearly the tools we have to control malaria, or the ways in which we are using them, are not working. The failure of existing methods for malaria control has sparked interest in several new approaches. These include better and cheaper antimalarial drugs [6], renewed efforts to find a vaccine [7], and the development of genetically modified mosquitoes (GMMs) designed either to reduce population sizes or to replace existing populations with vectors unable to transmit the disease. In this review we describe some of the efforts currently underway to create GMMs and assess some of the obstacles they face.

Can Monkeys Choose Optimally When Faced with Noisy Stimuli and Unequal Rewards?:

Decisions are commonly based on multiple sources of information. In a forced choice task, for example, sensory information about the identity of a stimulus may be combined with prior information about the amount of reward associated with each choice. We employed a well-characterized motion discrimination task to examine how animals combine such sources of information and whether they weigh these components so as to harvest rewards optimally. Two monkeys discriminated the direction of motion in a family of noisy random dot stimuli. The animals were informed before each trial whether reward outcomes were equal or unequal for the two alternatives, and if unequal, which alternative promised the larger reward. Predictably, choices were biased toward the larger reward in the unequal reward conditions. We develop a decision-making model that describes the animals’ sensitivities to the visual stimulus and permits us to calculate the choice bias that yields optimal reward harvesting. We find that the monkeys’ performance is close to optimal; remarkably, the animals garner 98%+ of their maximum possible rewards. This study adds to the growing evidence that animal foraging behavior can approach optimality and provides a rigorous theoretical basis for understanding the computations underlying optimality in this and related tasks.

My picks from ScienceDaily

Continue reading

Clock Quotes

Why does no one confess his sins? Because he is yet in them. It is for a man who has awoke from sleep to tell his dreams.
– Lucius Annaeus Seneca

My picks from ScienceDaily

Continue reading

Darwin on Twitter

Starting to trend up: see #4, #5 and #8:
screen.JPG

Happy Birthday Darwin – from Google

Today’s logo:
Darwin Google Logo.JPG

Clock Quotes

The Officers all seemed very weary of this place I am not surprised at it: it must be to them a place of exile: Last year there had been plenty of Quail to shoot, but this year they have not appeared; this resource exhausted, the last tie which bound them to existence, seemed on the point of being dissolved.
– Charles Robert Darwin, Beagle diary

New and Exciting in PLoS ONE

There are 17 new articles in PLoS ONE today. As always, you should rate the articles, post notes and comments and send trackbacks when you blog about the papers. You can now also easily place articles on various social services (CiteULike, Connotea, Stumbleupon, Facebook and Digg) with just one click. Here are my own picks for the week – you go and look for your own favourites:
Individual Recognition in Domestic Cattle (Bos taurus): Evidence from 2D-Images of Heads from Different Breeds:

In order to maintain cohesion of groups, social animals need to process social information efficiently. Visual individual recognition, which is distinguished from mere visual discrimination, has been studied in only few mammalian species. In addition, most previous studies used either a small number of subjects or a few various views as test stimuli. Dairy cattle, as a domestic species allow the testing of a good sample size and provide a large variety of test stimuli due to the morphological diversity of breeds. Hence cattle are a suitable model for studying individual visual recognition. This study demonstrates that cattle display visual individual recognition and shows the effect of both familiarity and coat diversity in discrimination. We tested whether 8 Prim’Holstein heifers could recognize 2D-images of heads of one cow (face, profiles, ¾ views) from those of other cows. Experiments were based on a simultaneous discrimination paradigm through instrumental conditioning using food rewards. In Experiment 1, all images represented familiar cows (belonging to the same social group) from the Prim’Holstein breed. In Experiments 2, 3 and 4, images were from unfamiliar (unknown) individuals either from the same breed or other breeds. All heifers displayed individual recognition of familiar and unfamiliar individuals from their own breed. Subjects reached criterion sooner when recognizing a familiar individual than when recognizing an unfamiliar one (Exp 1: 3.1±0.7 vs. Exp 2: 5.2±1.2 sessions; Z = 1.99, N = 8, P = 0.046). In addition almost all subjects recognized unknown individuals from different breeds, however with greater difficulty. Our results demonstrated that cattle have efficient individual recognition based on categorization capacities. Social familiarity improved their performance. The recognition of individuals with very different coat characteristics from the subjects was the most difficult task. These results call for studies exploring the mechanisms involved in face recognition allowing interspecies comparisons, including humans.

Compactness Determines the Success of Cube and Octahedron Self-Assembly:

Nature utilizes self-assembly to fabricate structures on length scales ranging from the atomic to the macro scale. Self-assembly has emerged as a paradigm in engineering that enables the highly parallel fabrication of complex, and often three-dimensional, structures from basic building blocks. Although there have been several demonstrations of this self-assembly fabrication process, rules that govern a priori design, yield and defect tolerance remain unknown. In this paper, we have designed the first model experimental system for systematically analyzing the influence of geometry on the self-assembly of 200 and 500 µm cubes and octahedra from tethered, multi-component, two-dimensional (2D) nets. We examined the self-assembly of all eleven 2D nets that can fold into cubes and octahedra, and we observed striking correlations between the compactness of the nets and the success of the assembly. Two measures of compactness were used for the nets: the number of vertex or topological connections and the radius of gyration. The success of the self-assembly process was determined by measuring the yield and classifying the defects. Our observation of increased self-assembly success with decreased radius of gyration and increased topological connectivity resembles theoretical models that describe the role of compactness in protein folding. Because of the differences in size and scale between our system and the protein folding system, we postulate that this hypothesis may be more universal to self-assembling systems in general. Apart from being intellectually intriguing, the findings could enable the assembly of more complicated polyhedral structures (e.g. dodecahedra) by allowing a priori selection of a net that might self-assemble with high yields.

Phytoliths Analysis for the Discrimination of Foxtail Millet (Setaria italica) and Common Millet (Panicum miliaceum):

Foxtail millet (Setaria italica) and Common millet (Panicum miliaceum) are the oldest domesticated dry farming crops in Eurasia. Identifying these two millets in the archaeobotanical remains are still problematic, especially because the millet grains preserve only when charred. Phytoliths analysis provides a viable method for identifying this important crop. However, to date, the identification of millet phytoliths has been questionable, because very little study has been done on their morphometry and taxonomy. Particularly, no clear diagnostic feature has been used to distinguish between Foxtail millet and Common millet. Here we examined the anatomy and silicon structure patterns in the glumes, lemmas, and paleas from the inflorescence bracts in 27 modern plants of Foxtail millet, Common millet, and closely related grasses, using light microscopy with phase-contrast and microscopic interferometer. Our research shows that five key diagnostic characteristics in phytolith morphology can be used to distinguish Foxtail millet from Common millet based on the presence of cross-shaped type, regularly arranged papillae, Ω-undulated type, endings structures of epidermal long cell, and surface ridgy line sculpture in the former species. We have established identification criteria that, when used together, give the only reliable way of distinguishing between Foxtail millet and Common millet species based on their phytoliths characteristics, thus making a methodological contribution to phytolith research. Our findings also have important implications in the fields of plant taxonomy, agricultural archaeology, and the culture history of ancient civilizations.

Ancient Horizontal Gene Transfer from Bacteria Enhances Biosynthetic Capabilities of Fungi:

Polyketides are natural products with a wide range of biological functions and pharmaceutical applications. Discovery and utilization of polyketides can be facilitated by understanding the evolutionary processes that gave rise to the biosynthetic machinery and the natural product potential of extant organisms. Gene duplication and subfunctionalization, as well as horizontal gene transfer are proposed mechanisms in the evolution of biosynthetic gene clusters. To explain the amount of homology in some polyketide synthases in unrelated organisms such as bacteria and fungi, interkingdom horizontal gene transfer has been evoked as the most likely evolutionary scenario. However, the origin of the genes and the direction of the transfer remained elusive. We used comparative phylogenetics to infer the ancestor of a group of polyketide synthase genes involved in antibiotic and mycotoxin production. We aligned keto synthase domain sequences of all available fungal 6-methylsalicylic acid (6-MSA)-type PKSs and their closest bacterial relatives. To assess the role of symbiotic fungi in the evolution of this gene we generated 24 6-MSA synthase sequence tags from lichen-forming fungi. Our results support an ancient horizontal gene transfer event from an actinobacterial source into ascomycete fungi, followed by gene duplication. Given that actinobacteria are unrivaled producers of biologically active compounds, such as antibiotics, it appears particularly promising to study biosynthetic genes of actinobacterial origin in fungi. The large number of 6-MSA-type PKS sequences found in lichen-forming fungi leads us hypothesize that the evolution of typical lichen compounds, such as orsellinic acid derivatives, was facilitated by the gain of this bacterial polyketide synthase.

Today’s carnivals

Linnaeus Legacy #16 is up on Seeds Aside
Carnival of the Liberals #84 is up on Submitted to a Candid World

User activity on PLoS ONE – an analysis

You may remember some time ago, we gave out the data to a few people in the community to take a look at the commenting function on PLoS ONE. Now, Euan Adie, using crowdsourcing (a big Thank You to 818 people who helped with this project) came up with the most detailed analysis to date. Well worth your time to take a look.

CALL TO ACTION: Ask your Representative to oppose the H.R. 801 – The Fair Copyright in Research Works Act

From The Alliance for Taxpayer Access:

CALL TO ACTION: Ask your Representative to oppose the H.R. 801 – The Fair Copyright in Research Works Act
February 11, 2009
Last week, the Chairman of the House Judiciary Committee (Rep. John Conyers, D-MI) re-introduced a bill that would reverse the NIH Public Access Policy and make it impossible for other federal agencies to put similar policies into place. The legislation is H.R. 801: the “Fair Copyright in Research Works Act” (http://thomas.loc.gov/cgi-bin/query/z?c111:H.R.801:).
All supporters of public access – researchers, libraries, campus administrators, patient advocates, publishers, and others – are asked to please contact your Representative no later than February 28, 2009 to express your support for public access to taxpayer-funded research and ask that he or she oppose H.R.801. Draft letter text is included below. As always, it’s important to let us know what action you’re able to take, via http://www.taxpayeraccess.org/action/log.html.
H.R. 801 is designed to amend current copyright law and create a new category of copyrighted works (Section 201, Title 17). In effect, it would:
1. Prohibit all U.S. federal agencies from conditioning funding agreements to require that works resulting from federal support be made publicly available if those works are either: a) funded in part by sources other than a U.S. agency, or b) the result of “meaningful added value” to the work from an entity that is not party to the agreement.
2. Prohibit U.S. agencies from obtaining a license to publicly distribute, perform, or display such work by, for example, placing it on the Internet.
3. Stifle access to a broad range of federally funded works, overturning the crucially important NIH Public Access Policy and preventing other agencies from implementing similar policies.
4. Because it is so broadly framed, the proposed bill would require an overhaul of the well-established procurement rules in effect for all federal agencies, and could disrupt day-to-day procurement practices across the federal government.
5. Repeal the longstanding “federal purpose” doctrine, under which all federal agencies that fund the creation of a copyrighted work reserve the “royalty-free, nonexclusive right to reproduce, publish, or otherwise use the work” for any federal purpose. This will severely limit the ability of U.S. federal agencies to use works that they have funded to support and fulfill agency missions and to communicate with and educate the public.
Because of the NIH Public Access Policy, millions of Americans now have access to vital health care information through the PubMed Central database. Under the current policy, nearly 3,000 new biomedical manuscripts are deposited for public accessibility each month. H.R.801 would prohibit the deposit of these manuscripts, seriously impeding the ability of researchers, physicians, health care professionals, and families to access and use this critical health-related information in a timely manner.
All supporters of public access — researchers, libraries, campus administrators, patient advocates, publishers, and others — are asked to contact their Representatives to let them know you support public access to federally funded research and oppose H.R. 801. Again, the proposed legislation would effectively reverse the NIH Public Access Policy, as well as make it impossible for other federal agencies to put similar policies into place.
Thank you for your support and continued persistence in supporting this policy. You know the difference constituent voices can make on Capitol Hill.
If you have any questions, don’t hesitate to contact Heather or myself anytime.
All best,
Jennifer
————————–
Jennifer McLennan
Director of Communications
SPARC
(The Scholarly Publishing & Academic Resources Coalition)
http://www.arl.org/sparc
(202) 296-2296 ext 121
jennifer [at] arl [dot] org
Please consider the environment before printing this e-mail.
————————-
Draft letter text:
Dear Representative;
On behalf of [your organization], I strongly urge you to oppose H.R. 801, “the Fair Copyright in Research Works Act,” introduced to the House Judiciary Committee on February 3, 2009. This bill would amend the U.S. Copyright Code, prohibiting federal agencies from requiring as a condition of funding agreements public access to the products of the research they fund. This will significantly inhibit our ability to advance scientific discovery and to stimulate innovation in all scientific disciplines.
Most critically, H.R. 810 would reverse the National Institutes of Health (NIH) Public Access Policy, prohibit American taxpayers from accessing the results of the crucial biomedical research funded by their taxpayer dollars, and stifle critical advancements in life-saving research and scientific discovery.
Because of the NIH Public Access Policy, millions of Americans now have access to vital health care information from the NIH’s PubMed Central database. Under the current policy, nearly 3,000 new biomedical manuscripts are deposited for public accessibility each month. H.R.801 would prohibit the deposit of these manuscripts, seriously impeding the ability of researchers, physicians, health care professionals, and families to access and use this critical health-related information in a timely manner.
H.R. 801 affects not only the results of biomedical research produced by the NIH, but also scientific research coming from all other federal agencies. Access to critical information on energy, the environment, climate change, and hundreds of other areas that directly impact the lives and well being of the public would be unfairly limited by this proposed legislation.
[Why you support taxpayer access and the NIH policy].
The NIH and other agencies must be allowed to ensure timely, public access to the results of research funded with taxpayer dollars. Please oppose H.R.801.
Sincerely,
(name)
[END LETTER TEXT]

My picks from ScienceDaily

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Clock Quotes

In saying that without the power of the state, evil men would rule over the good it is taken for granted that the good are precisely those who at the present time have power, and the bad the same who are now subjugated.
– Leo Nikolaevich Tolstoy

New and Exciting in PLoS ONE

There are 16 new articles in PLoS ONE today. As always, you should rate the articles, post notes and comments and send trackbacks when you blog about the papers. You can now also easily place articles on various social services (CiteULike, Connotea, Stumbleupon, Facebook and Digg) with just one click. Here are my own picks for the week – you go and look for your own favourites:
Genetic Determinants of Financial Risk Taking:

Individuals vary in their willingness to take financial risks. Here we show that variants of two genes that regulate dopamine and serotonin neurotransmission and have been previously linked to emotional behavior, anxiety and addiction (5-HTTLPR and DRD4) are significant determinants of risk taking in investment decisions. We find that the 5-HTTLPR s/s allele carriers take 28% less risk than those carrying the s/l or l/l alleles of the gene. DRD4 7-repeat allele carriers take 25% more risk than individuals without the 7-repeat allele. These findings contribute to the emerging literature on the genetic determinants of economic behavior.

Empathy Is Moderated by Genetic Background in Mice:

Empathy, as originally defined, refers to an emotional experience that is shared among individuals. When discomfort or alarm is detected in another, a variety of behavioral responses can follow, including greater levels of nurturing, consolation or increased vigilance towards a threat. Moreover, changes in systemic physiology often accompany the recognition of distressed states in others. Employing a mouse model of cue-conditioned fear, we asked whether exposure to conspecific distress influences how a mouse subsequently responds to environmental cues that predict this distress. We found that mice are responsive to environmental cues that predict social distress, that their heart rate changes when distress vocalizations are emitted from conspecifics, and that genetic background substantially influences the magnitude of these responses. Specifically, during a series of pre-exposure sessions, repeated experiences of object mice that were exposed to a tone-shock (CS-UCS) contingency resulted in heart rate deceleration in subjects from the gregarious C57BL/6J (B6) strain, but not in subjects from the less social BALB/cJ (BALB) strain. Following the pre-exposure sessions, subjects were individually presented with the CS-only for 5 consecutive trials followed by 5 consecutive pairings of the CS with the UCS. Pre-exposure to object distress increased the freezing responses of B6 mice, but not BALB mice, on both the CS-only and the CS-UCS trials. These physiological and behavioral responses of B6 mice to social distress parallel features of human empathy. Our paradigm thus has construct and face validity with contemporary views of empathy, and provides unequivocal evidence for a genetic contribution to the expression of empathic behavior.

Adverse Drug Reactions in Hospital In-Patients: A Prospective Analysis of 3695 Patient-Episodes:

Adverse drug reactions (ADRs) are a major cause of hospital admissions, but recent data on the incidence and clinical characteristics of ADRs which occur following hospital admission, are lacking. Patients admitted to twelve wards over a six-month period in 2005 were assessed for ADRs throughout their admission. Suspected ADRs were recorded and analysed for causality, severity and avoidability and whether they increased the length of stay. Multivariable analysis was undertaken to identify the risk factors for ADRs. The 5% significance level was used when assessing factors for inclusion in multivariable models. Out of the 3695 patient episodes assessed for ADRs, 545 (14.7%, 95% CI 13.6-15.9%) experienced one or more ADRs. Half of ADRs were definitely or possibly avoidable. The patients experiencing ADRs were more likely to be older, female, taking a larger number of medicines, and had a longer length of stay than those without ADRs. However, the only significant predictor of ADRs, from the multivariable analysis of a representative sample of patients, was the number of medicines taken by the patient with each additional medication multiplying the hazard of an ADR episode by 1.14 (95% CI 1.09, 1.20). ADRs directly increased length of stay in 147 (26.8%) patients. The drugs most frequently associated with ADRs were diuretics, opioid analgesics, and anticoagulants. In conclusion, approximately one in seven hospital in-patients experience an ADR, which is a significant cause of morbidity, increasing the length of stay of patients by an average of 0.25 days/patient admission episode. The overall burden of ADRs on hospitals is high, and effective intervention strategies are urgently needed to reduce this burden.

Darwin Day in the Blogosphere

Lots of excitement this week on science blogs and other fans of reality.
The biggest biggy of the biggest biggies is Blog For Darwin blog swarm – submit your entries here.
But there are some other, smaller initiatives out there. For instance, this Darwin Meme. And Darwinfest haiku contest.
And if you are blogging more seriously and sholarly about Darwin’s place in history, or his publications, then certainly that would fit into the next Giant’s Shoulders carnival.
On Twitter, follow and use the #Darwin hashtag. On FriendFeed, I am assuming that the Life Scientists room will be the place to go.

Darwin’s Legacy: Evolution’s Impact on Science and Culture – a student conference at UNC-W

This will be on the campus of UNC Wilmington and I’ll do my best to be there if possible:

Darwin’s Legacy: Evolution’s Impact on Science and Culture
March 19-21, 2009
UNCW’s Evolution Learning Community will be hosting “Darwin’s Legacy: Evolution’s Impact on Science and Culture,” a multidisciplinary student conference on March 19-21, 2009.
The conference will be a unique opportunity for undergraduate and graduate students in the natural sciences, social sciences, humanities and arts who are conducting research or creative endeavors related to evolution to present their research, investigate graduate study opportunities, network, enhance their resumes, and enrich the body of knowledge surrounding evolution.
With the exception of the four keynote speakers, all presentations will be made by students.
Keynote Speakers:
Dr. David Buss, University of Texas
Dr. Peter Carruthers, University of Maryland
Dr. David Mindell, California Academy of Sciences
Dr. Kevin Padian, University of California, Berkeley

Ah, that Conyers bill again!

The Conyers bill (a.k.a. Fair Copyright in Research Works Act, HR 801), is back. Despite all the debunking it got last time around, and despite the country having more important problems to deal with right now, this regressive bill, completely unchanged word-for-word, is apparently back again. It is the attempt by TA publishers, through lies and distortions, to overturn the NIH open access policy. Here are some reactions – perhaps Rep.Conyers and colleagues should get an earful from us….
Peter Suber, in Comments on the Conyers bill provides all the useful links, plus some of the blogospheric responses.
Greg Laden: Open Access Under Threat (also interesting discussion in the comments):

The publishing industry is dangerous. Why? Because it is big and rich, but it is also in danger. The publishing industry, like the music industry, and like the commercial proprietary software industry, faces structural reorganization of the markets served and uncertainty in the flow of cash into coffers. So we should not be surprised when we see the industry buying off members of congress to get legislation passed that protects the industry from change that is coming. Change the industry does not want to see.

The Scientist: Anti-open access bill is back:

A bill aimed at undoing the NIH’s mandate to make federally-funded research manuscripts freely available on PubMed Central within a year of publication was re-introduced in the US House of Representatives on Tuesday night (Feb. 3).
The legislation claims that the NIH policy breaches existing copyright laws that protect academic publishers. If passed, the bill would stop federal agencies from requiring the transfer of copyright as a stipulation of investigators receiving taxpayer-backed grants.

Campus Entrepreneurship: Monopoly Rights to Taxpayer Funded Research?:

This sounds like monopoly rights for publicly funded knowledge. Please contact representative John Conyers (MI) and ask him to stop pushing this bill. His co-sponsors on the bill appear to be Steve Cohen of TN, Trent Franks of AZ, Darrell Issa (CA), and Robert Wexler of FL. (BTW, should anyone representing Michigan be spending their time on this? Dereliction of duty?)

David Bruggeman: Bill Introduced to Roll Back NIH Open Access:

There is a legislative effort to push back the move toward open access in scientific publishing. Representative John Conyers, chair of the House Judiciary Committee, has introduced a bill to roll back the National Institutes of Health requirement that its grantees provide a copy of their peer-reviewed articles to be published in PubMed Central, a free online database. The competing interests in this issue (and similar efforts to make federally funded research more available to the public) are the copyright interests of the journals (which are typically assigned them by the authors) and an interest in making research – especially that funded by citizens’ tax dollars – more accessible to the public.
I lean toward the latter, but I suspect that journals will be forced to revamp their publication models and business plans long after newspapers do, even though there are some similarities in how online access to information has undercut their respective market advantages.

Michael Eisen: Conyers reintroduces bill to kill NIH Public Access Policy:

As many have pointed out, the whole premise of the bill is absurd. Publishers are arguing that the NIH has taken their copyright. But, of course, if that were true, they would already have protection under federal copyright law, and they would be suing the government. Instead, they are pushing legislation that would actually remove the governments right to distribute work it funds, thereby clearly demonstrating that they believe the government’s action is perfectly legal under copyright law.
What is particularly galling is that Conyers held hearings on this bill last year, in which a LOT of important issues were raised about the bill, and there were many on the committee who were skeptical about it. So, what does Conyers do with all that useful feedback? He ignores it, and introduces exactly the same bill in the new Congress. One hopes such an ill-conceived piece of public policy would have no hope when Congress has many more important things on its hands, but one never knows. Let’s hope it dies in committee. But just to be safe, let the members know how you feel.
It’s hard to know why Conyers is doing this. He receives some modest contributions from Elsevier and some others in the publishing industry – but it’s hard to imagine $4,000 buys a piece of legislation. Conyers has recently reorganized the House Judiciary Committee in order to take control of intellectual property cases, so maybe this is part of a more broadly orchestrated “defense” of copyright.

Related – Questionable Authority: Way To Support Science, Reed Elsevier:

Reed Elsevier is one of the leading – if not the leading – publishers of scientific journals. They make profits on the scale of thousands of dollars a minute selling these journals to libraries so that scientists can read them. They have, I’d suggest, some motivation to keep from pissing scientists off any more than necessary.
Which is why I was almost surprised to discover that Reed Elsevier Inc. gave Senator Inhofe $16,500 in 2008, with $3,000 of that coming right from their own Political Action Committee. It’s nice to know that Reed Elsevier is always ready to stand behind scientists. With a knife in their hand.

Bus Slogan Generator

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Join the North Carolina group on Nature Network

Remember a couple of weeks ago, when I complained that Triangle is too narrow a term for a Hub at Nature Network, as there is really no humongous city where everything is centered but the science is distributed all around the state of North Carolina, with people collaborating with each other and traveling back and forth between various regions of the state.
Well, now, to reflect that situation, the Triangle group on Nature Network was renamed the North Carolina group. If it grows in size, it may one day become a proper Hub. So, if you are in any way interested in science and live anywhere in the state of North Carolina, please register and check North Carolina as your geographical location and group.

Google Peer Review!?

This appears to be from Google: GPeerReview:

We intend for the peer-review web to do for scientific publishing what the world wide web has done for media publishing. As it becomes increasingly practical to evaluate researchers based on the reviews of their peers, the need for centralized big-name journals begins to diminish. The power is returned to those most qualified to give meaningful reviews: the peers. As long as big journals provide a useful service, this tool will only enhance their effectiveness. But the more they take months to review our publications, and the more they give unqualified reviews, and the more they force us to clear irrelevant hurdles prior to publication, and the more they lock up our works behind fees and copyright transfers, the more this tool will provide an alternative to their services.

What do you all think?

Darwin Day on Twitter

No, really, it was Anne-Marie’s idea. She started it! Yeah, don’t look at me!
Charles Darwin is on Twitter, Alfred Wallace is on Twitter, Richard Owen is on Twitter, even Bishop Wilberforce (aka Soapy Sam) is on Twitter. Where is Huxley?
We are already having fun retweeting non-existent Darwin tweets 😉 I hope the real Darwin and others respond with humorous stuff:
@BoraZ I can see it; “@arwallace: damn!”
Bora: @rowen next time I’ll block you!
BoraZ: RT @cdarwin Please: need info on modification/domestication in pigeons for a book
BoraZ: RT @cdarwin w00t! Going on a cruise: Argentina, Galapagos, Australia! + dining with the Captain every day!
BoraZ: RT @cdarwin: @thhuxley – remember that @bishop_wilberforce is a troll.
BoraZ: Oh, Wilberforce is here: @SoapySam God has delivered him into my hands 😉
#Darwin is the proper hashtag on Twitter for this week’s celebrations, so dig in!

My picks from ScienceDaily

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